In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: In order to test this possibility we have analyzed four heterozygotes for class I G6PD mutations two with G6PD Portici ( 1178G - - > A ) and two with G6PD Bari ( 1187C - - > T ) .
### Output Text:
In order to test this possibility we have analyzed four heterozygotes for class I G6PD mutations two with G6PD Portici ( 1178G - - > A ) and two with G6PD Bari ( 1187C - - > T ) . 