In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Mutations of the BRCA1 gone in humans are associated with predisposition to breast and ovarian cancers .
### Output Text:
Mutations of the BRCA1 gone in humans are associated with predisposition to <span class="disease">breast and ovarian cancers</span> . 