In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: However , our data suggest that the Arg356 allele may have a different genotype distribution in breast cancer patients from that in controls ( Arg356 homozygotes are more frequent in the control groups , P = 0 . 01 ) , indicating that it may be protective against breast cancer .
### Output Text:
However , our data suggest that the Arg356 allele may have a different genotype distribution in <span class="disease">breast cancer</span> patients from that in controls ( Arg356 homozygotes are more frequent in the control groups , P = 0 . 01 ) , indicating that it may be protective against <span class="disease">breast cancer</span> . 