In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Q188R accounted for 60 % , K285N accounted for 28 % of these alleles .
### Output Text:
Q188R accounted for 60 % , K285N accounted for 28 % of these alleles . 