In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Identification and expression of eight novel mutations among non - Jewish patients with Canavan disease .
### Output Text:
Identification and expression of eight novel mutations among non - Jewish patients with <span class="disease">Canavan disease</span> . 