In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: In the adult , type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin .
### Output Text:
In the adult , type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin . 