In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Here we investigate the rate of BRCA2 mutation in sporadic breast cancers and in a set of cell lines that represent twelve other tumour types .
### Output Text:
Here we investigate the rate of BRCA2 mutation in <span class="disease">sporadic breast cancers</span> and in a set of cell lines that represent twelve other <span class="disease">tumour</span> types . 