In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Loss of heterozygosity was studied in seven renal hamartomas from two affected individuals in the first family , as well as in a jaw tumor and a parathyroid tumor from the second family .
### Output Text:
Loss of heterozygosity was studied in seven <span class="disease">renal hamartomas</span> from two affected individuals in the first family , as well as in a <span class="disease">jaw tumor</span> and a <span class="disease">parathyroid tumor</span> from the second family . 