In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Western blot analysis of lymphoblastoid cell lines derived from affected family members from this kindred , as well as from a previously reported Swiss family carrying a frameshift mutation at codon 1987 and displaying a similar attenuated phenotype , showed only the wild - type APC protein .
### Output Text:
Western blot analysis of lymphoblastoid cell lines derived from affected family members from this kindred , as well as from a previously reported Swiss family carrying a frameshift mutation at codon 1987 and displaying a similar attenuated phenotype , showed only the wild - type <span class="disease">APC</span> protein . 