In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The eight novel mutations identified included 1 - and 4 - bp deletions ( 32 deltaT and 876 deltaAGAA , respectively ) and I16T , G27R , D114E , G123E , C152Y , and R168C missense mutations .
### Output Text:
The eight novel mutations identified included 1 - and 4 - bp deletions ( 32 deltaT and 876 deltaAGAA , respectively ) and I16T , G27R , D114E , G123E , C152Y , and R168C missense mutations . 