In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Two alternative HMGIC / LPP hybrid transcripts have been detected ; the difference between them is mainly the presence of either two or three LIM domains in the predicted HMGI - C / LPP fusion proteins . .
### Output Text:
Two alternative HMGIC / LPP hybrid transcripts have been detected ; the difference between them is mainly the presence of either two or three LIM domains in the predicted HMGI - C / LPP fusion proteins . . 