In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer .
### Output Text:
The TSG101 <span class="disease">tumor</span> susceptibility gene is located in chromosome 11 band p15 and is mutated in human <span class="disease">breast cancer</span> . 