In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The haplotype has been found in combination with a number of other haplotypes containing defective genes that lead either to C6 or C7 deficiency , but with different consequences .
### Output Text:
The haplotype has been found in combination with a number of other haplotypes containing defective genes that lead either to <span class="disease">C6 or C7 deficiency</span> , but with different consequences . 