In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: To determine the molecular basis of Type II deficiency the two Type II C2Q0 genes were isolated and transfected separately into L - cells .
### Output Text:
To determine the molecular basis of <span class="disease">Type II deficiency</span> the two Type II C2Q0 genes were isolated and transfected separately into L - cells . 