In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The von Hippel - Lindau tumor suppressor gene ( VHL ) has a critical role in the pathogenesis of clear - cell renal cell carcinoma ( RCC ) , as VHL mutations have been found in both von Hippel - Lindau disease - associated and sporadic RCCs .
### Output Text:
The <span class="disease">von Hippel - Lindau tumor</span> suppressor gene ( VHL ) has a critical role in the pathogenesis of <span class="disease">clear - cell renal cell carcinoma</span> ( <span class="disease">RCC</span> ) , as VHL mutations have been found in both <span class="disease">von Hippel - Lindau disease - associated and sporadic RCCs</span> . 