In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: These common mutations have an etiological role in many breast and ovarian cancer cases and provide the opportunity to examine genotype - phenotype correlations and genotype - environment interactions in individuals with the identical BRCA1 lesion .
### Output Text:
These common mutations have an etiological role in many <span class="disease">breast and ovarian cancer</span> cases and provide the opportunity to examine genotype - phenotype correlations and genotype - environment interactions in individuals with the identical BRCA1 lesion . 