In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: In addition , 15 papillary renal cell tumours and ten renal oncocytomas , which are characterized by genetic changes other than loss of chromosome 3p sequences , were analysed for mutation of the VHL gene .
### Output Text:
In addition , 15 <span class="disease">papillary renal cell tumours</span> and ten <span class="disease">renal oncocytomas</span> , which are characterized by genetic changes other than loss of chromosome 3p sequences , were analysed for mutation of the <span class="disease">VHL</span> gene . 