In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Loss of the wild - type allele in > 90 % of tumors from patients with inherited BRCA1 mutations indicates tumor suppressive function .
### Output Text:
Loss of the wild - type allele in > 90 % of <span class="disease">tumors</span> from patients with inherited BRCA1 mutations indicates <span class="disease">tumor</span> suppressive function . 