In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: We have examined the frequency of four of these polymorphisms Gln356Arg , Pro871Leu , Glu1038Gly and Ser1613Gly in large series of breast and ovarian cancer cases and matched controls .
### Output Text:
We have examined the frequency of four of these polymorphisms Gln356Arg , Pro871Leu , Glu1038Gly and Ser1613Gly in large series of <span class="disease">breast and ovarian cancer</span> cases and matched controls . 