In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Identification of WASP mutations , mutation hotspots and genotype - phenotype disparities in 24 patients with the Wiskott - Aldrich syndrome .
### Output Text:
Identification of WASP mutations , mutation hotspots and genotype - phenotype disparities in 24 patients with the <span class="disease">Wiskott - Aldrich syndrome</span> . 