In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The aim of the present study was to determine if it might also be altered in colorectal cancers .
### Output Text:
The aim of the present study was to determine if it might also be altered in <span class="disease">colorectal cancers</span> . 