In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: No correlation between the location of frameshift or nonsense mutations and phenotypic features , including age at diagnosis , the number of tumor foci , and manifestation of nonocular tumors was observed . .
### Output Text:
No correlation between the location of frameshift or nonsense mutations and phenotypic features , including age at diagnosis , the number of <span class="disease">tumor</span> foci , and manifestation of <span class="disease">nonocular tumors</span> was observed . . 