In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: A sex - dependent penetrance of primary HPT , resulting in predominantly male - affected cases was evident in the two families .
### Output Text:
A sex - dependent penetrance of <span class="disease">primary HPT</span> , resulting in predominantly male - affected cases was evident in the two families . 