In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Targeted disruption of ATM leads to growth retardation , chromosomal fragmentation during meiosis , immune defects , and thymic lymphoma .
### Output Text:
Targeted disruption of ATM leads to <span class="disease">growth retardation</span> , <span class="disease">chromosomal fragmentation during meiosis</span> , <span class="disease">immune defects</span> , and <span class="disease">thymic lymphoma</span> . 