In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: We describe a novel family with ALPS in which three affected siblings carry two distinct missense mutations on both the Fas gene alleles and show lack of Fas - induced apoptosis .
### Output Text:
We describe a novel family with <span class="disease">ALPS</span> in which three affected siblings carry two distinct missense mutations on both the Fas gene alleles and show lack of Fas - induced apoptosis . 