In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: In 7 of 15 uncultured primary human breast carcinomas , intragenic deletions were shown in TSG101 genomic DNA and transcripts by gel and sequence analysis , and mutations affecting two TSG101 alleles were identified in four of these cancers .
### Output Text:
In 7 of 15 uncultured primary human <span class="disease">breast carcinomas</span> , intragenic deletions were shown in TSG101 genomic DNA and transcripts by gel and sequence analysis , and mutations affecting two TSG101 alleles were identified in four of these <span class="disease">cancers</span> . 