In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: Nucleotide sequence analysis of a composite cDNA of LPP revealed an open reading frame of 1836 nucleotides encoding a proline - rich protein containing a leucine - zipper motif in its amino - terminal region and three LIM domains in its carboxy - terminal region .
### Output Text:
Nucleotide sequence analysis of a composite cDNA of LPP revealed an open reading frame of 1836 nucleotides encoding a proline - rich protein containing a leucine - zipper motif in its amino - terminal region and three LIM domains in its carboxy - terminal region . 