In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="disease"> to denote a disease.

### Input Text: The BARD1 / BRCA1 interaction is disrupted by BRCA1 missense mutations that segregate with breast cancer susceptibility , indicating that BARD1 may be involved in mediating tumour suppression by BRCA1 . .
### Output Text:
The BARD1 / BRCA1 interaction is disrupted by BRCA1 missense mutations that segregate with <span class="disease">breast cancer</span> susceptibility , indicating that BARD1 may be involved in mediating <span class="disease">tumour</span> suppression by BRCA1 . . 