text: Proteins sent to this organelle may be bound by the heat shock protein BiP ["b-i-p"].
full_question: Proteins sent to this organelle may be bound by the heat shock protein BiP ["b-i-p"]. Vesicles destined for retrograde transport to this organelle are coated with COPI ["cop-one"]. Proteins with the KDEL ["k-dell"] sequence cannot leave this organelle until it is cleaved off. In this organelle, PDI reacts with cysteine residues to form disulfide bonds. The membrane of this organelle is continuous with that of the nucleus. A form of this organelle found in the muscles stores calcium ions. One type of this organelle is involved in lipid metabolism and detoxification, while the other is named for the ribosomes studding its surface. For 10 points name this organelle with smooth and rough varieties.
first_sentence: Proteins sent to this organelle may be bound by the heat shock protein BiP ["b-i-p"].
raw_answer: endoplasmic reticulum [or ER; accept smooth endoplasmic reticulum; accept rough endoplasmic reticulum; accept sarcoplasmic reticulum]