This reaction produces putrescine in the committed step of polyamine synthesis.
This reaction produces putrescine in the committed step of polyamine synthesis. A single function enzyme that catalyzes this reaction on orotodine monophosphate in yeast and bacteria is paired with a phospho-ribosyl- transferase in UMP synthase in mammals. The enzyme with the highest catalytic proficiency of any enzyme known carries out this reaction on uro-porphyrin- ogen. An enzyme carrying out this reaction has isoforms with molecular weights 65 and 67 kD, and is frequently targeted by autoantibodies used as a biomarker for type 1 diabetes. In fermentation, acetaldehyde is produced from pyruvate via this type of reaction, which also converts histidine to histamine. The physiologically most famous reaction of this kind convertsan excitatory neurotransmitter into an inhibitory one. For 10 points, name this reaction that converts glutamate to GABA via the removal of CO2.
This reaction produces putrescine in the committed step of polyamine synthesis.
decarboxylation [or word forms; or removal of CO2 before mentioned; do not accept or prompt on "carboxylation"]