Proteins that bind this molecule typically have a three-part motif consisting of spaced GXXXXGK, DXXG, and NKXD consensus sequences.
Proteins that bind this molecule typically have a three-part motif consisting of spaced GXXXXGK, DXXG, and NKXD consensus sequences. One protein that breaks down this molecule is inhibited by both Pseudomonas exotoxin A and  diptheria toxin. Disassembly of the COPII coat in new vesicles is triggered by ARF and Sar1p breaking down this molecule. In the nucleus, its breakdown causes importins to dissociate from, and exportins to associate with, their cargo. The breakdown of this molecule causes the counterclockwise rotation of the small ribosomal subunit by the protein EF2. GEFs ["Geffs" with a hard "g"] promote the dissociation of one product of its breakdown, and its breakdown is activated by GAPs ["gaps"]. Rab and Ran, which are part of the Ras superfamily, break down this molecule. Seven-transmembranereceptors are coupled to heterotrimeric proteins whose alpha subunit binds to and breaks down this molecule, called G proteins. For 10 points, name this purine triphosphate that is not ATP. 
Proteins that bind this molecule typically have a three-part motif consisting of spaced GXXXXGK, DXXG, and NKXD consensus sequences.
GTP or guanosine triphosphate