Mutations in the HNF or PDX1 genes can lead to a moderately-late onset form of this disease.
Mutations in the HNF or PDX1 genes can lead to a moderately-late onset form of this disease. Mice develop this disease after being subjected to high levels of streptozotocin. Many sufferers of stiff person syndrome will develop this disease, which like SPS causes high levels of GAD antibodies. Low levels of a 31 amino-acid connecting chain called the C-peptide are found in people suffering from one form of this disease, which can be treated by metformin. The leading cause of blindness in young American adults is the retinopathy caused by this disease. A lack of production of a certain hormone in the beta cells of the pancreas characterizes this disease's type 1. For 10 points, name this disease in which the failure of insulin signaling leads to high blood sugar.
Mutations in the HNF or PDX1 genes can lead to a moderately-late onset form of this disease.
diabetes mellitus [or type 1 diabetes mellitus; or type 2 diabetes mellitus]