When this process occurs during nucleophilic addition of Grignard (green-YAHR) reagents to alpha- chiral carbonyls, it results in the product having opposite stereochemistry to that predicted by the AnhÂ–Eisenstein stereoelectronic model.
When this process occurs during nucleophilic addition of Grignard (green-YAHR) reagents to alpha- chiral carbonyls, it results in the product having opposite stereochemistry to that predicted by the AnhÂ–Eisenstein stereoelectronic model. This process can be exploited to template ethylene glycol oligomers for efficient crown ether synthesis. Like the macrocyclic effect, this process can be considered as a result of a higher degree of ligand (LIG-ind) set preorganization. This process requires ligands that can have a denticity of two or greater. A manifestation of this process is the displacement of ammonia by ligands such as TMEDA and ethylene diamine. This process explains the effectiveness of EDTA as a ligand. Multiple sites on a ligand bind to a single guest in it. For 10 points, a type of therapy named for what process is often used to treat heavy metal poisoning?
When this process occurs during nucleophilic addition of Grignard (green-YAHR) reagents to alpha- chiral carbonyls, it results in the product having opposite stereochemistry to that predicted by the AnhÂ–Eisenstein stereoelectronic model.
chelation [or chelate effect; or word forms]