text: Formation of this tissue depends on the inactivation of the RANKL-RANK binding interaction.
full_question: Formation of this tissue depends on the inactivation of the RANKL-RANK binding interaction. Sharpey's fibers connect this tissue to its outer membrane. The loss of this tissue can be visualized by DEXA scans, and can be treated by a class of drugs called bisphosphonates. Volkmann's canals connect the functional unit of one type of this tissue, which consists of concentric (*) lamellae arranged around a central Haversian canal. The adjectives flat, irregular, short, sesamoid, and long describe the possible shapes of this tissue. This tissue consists of inorganic carbonated hydroxyapatite. It is synthesized by and resorbed by osteoblasts and osteoclasts, respectively. For 10 points, name this hard connective tissue that makes up the skeletal system.
first_sentence: Formation of this tissue depends on the inactivation of the RANKL-RANK binding interaction.
raw_answer: bone [or osseus tissue; accept spongy bone; accept cancellous bone; accept trabecular bone; prompt on connective tissue]