One variant of this reaction uses trifluoroacetic anhydride as an activating agent, allowing for this reaction to take place at a higher temperature.
One variant of this reaction uses trifluoroacetic anhydride as an activating agent, allowing for this reaction to take place at a higher temperature. This reaction takes place at minus sixty degrees celsius in order to avoid side products due to the Pummerer rearrangement. Another variant of this reaction uses N-chlorosuccinimide followed by workup with trimethylamine. This reaction proceeds through generation of an alkoxysulphonium ion, which then fragments to give an aldehyde and a foul-smelling side product. For 10 points, name this variant of the Corey-Kim reaction that transforms alcohols to aldehydes through the use of DMSO and oxalyl chloride, an oxidation named for an American chemist.
One variant of this reaction uses trifluoroacetic anhydride as an activating agent, allowing for this reaction to take place at a higher temperature.
Swern oxidation [or Swern reaction]