An eleven step synthesis of this compound with poor stereoselective control was devised by Milan Uskokovich.
An eleven step synthesis of this compound with poor stereoselective control was devised by Milan Uskokovich. The conversionof a silyl protecting group to a mesyl one enables the fiÂnal ring closure in another synthesis of this compound. Thiscompound is the end product of a six-step procedure involving the addition of aluminum powder, devised by Paul Rabe, whodetermined its connectivity, but was criticized because nobody could repeat his results. In 1853, Louis Pasteur obtained a newcompound by subjecting this compound to acid-catalyzed isomerization. Using Prelog's interconversion of an allyl piperidineto a related compound, W.E. Doring and Bob Woodward came up with a total synthesis which won them public attentiondue to this compound's wartime scarcity. A gamma-lactone was used as the starting product of Stork's stereoselective synthesisof this compound, accomplished nearly two centuries aftfter it was isolated from the cinchona tree. For 10 points, name this alkaloid with anti-malarial properties.
An eleven step synthesis of this compound with poor stereoselective control was devised by Milan Uskokovich.
quinine