An enzyme in the ADAT family is needed for the synthesis of these molecules, and their attachment is catalyzed by the hydrolysis of a GTP molecule attached to the EF-Tu protein.
An enzyme in the ADAT family is needed for the synthesis of these molecules, and their attachment is catalyzed by the hydrolysis of a GTP molecule attached to the EF-Tu protein. Robert Holley's 1968 Nobel Prize in Medicine came in part due to his discovery of the structure of these molecules, which contain several nonstandard bases like inosine and pseudouridine.  Their L-shaped structure allows them to fit into P and A sites, and the "wobble" hypothesis accounts for the extra amino acids that may be carried by the roughly 40 different types of these molecules. FTP, name these small chains of nucleotides that add an amino acid attached to their anticodon region to a polypeptide chain at a ribosome, usually drawn with a cloverleaf structure.
An enzyme in the ADAT family is needed for the synthesis of these molecules, and their attachment is catalyzed by the hydrolysis of a GTP molecule attached to the EF-Tu protein.
{t}ransfer {RNA}