The namesake reagent in this reaction was notably used to synthesize chamaecin, which inhibits oxidation of L-DOPA catalyzed by mushroom tyrosinase.
The namesake reagent in this reaction was notably used to synthesize chamaecin, which inhibits oxidation of L-DOPA catalyzed by mushroom tyrosinase. Sometimes also named for Arnold, this reaction provided the pathway for a namesake cyclization which synthesizes pyrazole derivatives, and it accomplishes the same general result as a Reimer-Tiemann reaction or a Duff reaction. Its reagent is a weakly electrophilic chloroiminium salt, prepared from anhydrous DMF and phosphorous oxychloride. Those compounds are used to formylate an activated aromatic or heterocyclic compound. FTP, name this reaction often named for two people, which produces aryl aldehydes and ketones. 
The namesake reagent in this reaction was notably used to synthesize chamaecin, which inhibits oxidation of L-DOPA catalyzed by mushroom tyrosinase.
Vilsmeier-Haack Reaction