The peptidase PÂ·CÂ·SÂ·KÂ·9 targets one receptor for this molecule whose absorption in the small intestine is also reduced by the drug ezetimibe ["eh-ZET-i-mibe"].
The peptidase PÂ·CÂ·SÂ·KÂ·9 targets one receptor for this molecule whose absorption in the small intestine is also reduced by the drug ezetimibe ["eh-ZET-i-mibe"]. One intermediate in the biosynthesis of this molecule is formed when geranyl transferase catalyzes the condensation of IÂ·PÂ·P into DMAPP [D-"map"]. That pathway for the synthesis of this molecule begins with the conversion of acetyl-CoÂ·A to mevÂ·alÂ·onate, and is the target of drugs inhibiting (*) HÂ·MÂ·G-CoÂ·A reductase. AÂ·pÂ·oÂ·B-100 is the primary transporter for this molecule in the body. Excess ingestion of this compound by M-2 macrophages leads to the formation of foam cells, which are a common symptom of one disease resulting from the accumulation of this substance. Incorporation of this molecule into cell membranes is vital for maintaining fluidity across temperature ranges. For 10 points, name this important lipid carried in the body by HDL and LDL.
The peptidase PÂ·CÂ·SÂ·KÂ·9 targets one receptor for this molecule whose absorption in the small intestine is also reduced by the drug ezetimibe ["eh-ZET-i-mibe"].
cholesterol [or LDLs or HDLs; prompt on general answers like "lipids" or "plaques" due to the atherosclerosis clue] 