Mutations in this pathway can be exacerbated by drugs like primaquine, which increase the production of hydrolases.  
Mutations in this pathway can be exacerbated by drugs like primaquine, which increase the production of hydrolases.  The enzyme gluconolactonase acts in its second step. The coenzyme form of thiamine, TPP, is needed for the function of an enzyme in this pathway that transfers two-carbon units from a ketose to an aldose to produce the final products. That enzyme acts with another enzyme in this pathway to convert xylulose and ribulose derivatives into the final products; those enzymes are transaldolase and transketolase. The byproducts of this pathway are intermediates during gluconeogenesis and glycolysis, and it is the primary catabolic pathway for production of NADPH. For 10 points, name this pathway that produces fructose-6-phosphate and glyceraldehyde-3-phosphate using a namesake phosphorylated five-carbon intermediate.
Mutations in this pathway can be exacerbated by drugs like primaquine, which increase the production of hydrolases.  
pentose phosphate pathway [or shunt, or phosphogluconate pathway/shunt, or hexose monophosphate pathway/shunt] 