Like amines, this functional group is often protected during organic syntheses by adding trimethylsilyl chloride.
Like amines, this functional group is often protected during organic syntheses by adding trimethylsilyl chloride. This functional group can result from reducing an ester with lithium aluminum hydride and from opening an epoxide. This group usually has a pKa between 16 and 19 and can be deprotonated and reacted with alkyl halides to form ethers. Secondary ones can be oxidized to ketones, whereas primary ones are oxidized to aldehydes. Ingestion of the simplest molecule containing this group can cause blindness, and with an ethyl group this group forms a popular intoxicant. For 10 points, name this functional group, which consists of an oxygen bonded to a hydrogen.
Like amines, this functional group is often protected during organic syntheses by adding trimethylsilyl chloride.
{hydroxyl} [or {alcohol}]