The Ran gradient controls availability of this structure's assembly factors, including TRX and NuMA.
The Ran gradient controls availability of this structure's assembly factors, including TRX and NuMA. In C. elegans, par genes regulate this structure's orientation and help guide the formation of P granules. Members of the bimC family of proteins help to form this structure when they are activated by Aurora A. The cyclosome's activity is inhibited by a checkpoint regulated by the Mad and Bub proteins which is named for this structure. This structure is destroyed by vinblastine and colchicine, which are sometimes referred to as "poisons" of microtubules and this structure. The metaphase plate is at the midpoint of this structure, and its fibers attach to kinetochores. For 10 points, name this collection of proteins and microtubules organized by centrosomes that moves chromosomes to opposite poles during mitosis and meiosis.
The Ran gradient controls availability of this structure's assembly factors, including TRX and NuMA.
mitotic or meiotic spindles [or spindle apparati; accept word forms]