Changes in it can lead to MNGIE, MELAS, NARP, and Leigh's syndrome, and Leber hereditary optic neuropathy.
Changes in it can lead to MNGIE, MELAS, NARP, and Leigh's syndrome, and Leber hereditary optic neuropathy. Deletions early in life lead to Pearson syndrome, while deletions in adulthood cause Kearns-Sayre syndrome. Arabidopsis thaliana has the largest known one while Plasmodium falciparum has the smallest, though the one found in Reclinomonas americana has the most genes. The HVR1 and HVR2 regions are of most interest to genealogists, as well as the fact that paternal ones are marked with ubiquitin to be destroyed. Therefore, they are almost always inherited from the mother. Coding for such proteins as cytochrome c oxidase, this is, FTP, what circular genome found in its namesake organelle?
Changes in it can lead to MNGIE, MELAS, NARP, and Leigh's syndrome, and Leber hereditary optic neuropathy.
{mitochondrial DNA} or {mtDNA} (prompt on “mitochondria” before “Deletions”)