This autosomal recessive disorder is caused by a genetic mutation in the neurotrophic tyrosine kinase receptor, or NTRK1 gene, which is a receptor for nerve growth factor.
This autosomal recessive disorder is caused by a genetic mutation in the neurotrophic tyrosine kinase receptor, or NTRK1 gene, which is a receptor for nerve growth factor. That mutation leads to defective nerve function in patients with this disorder that often includes features such as chronic bone and joint infection, fractures, and scarring of the tongue, lips and gums. There are currently no known cures or treatments for this disorder, though naloxone is now being used experimentally. People with this disorder rarely pass age 25, often due to their inability to sweat, which leads to the development of hypothermia. For 10 points, name this rare nervous system disorder in which sufferers are unable to feel pain.
This autosomal recessive disorder is caused by a genetic mutation in the neurotrophic tyrosine kinase receptor, or NTRK1 gene, which is a receptor for nerve growth factor.
congenital insensitivity to pain with anhidrosis or CIPA  or hereditary sensory and autonomic neuropathy type IV or HSAN IV  KV