Deficiency of ADAMTS13 leads to abnormally large multimers of a certain protein central to thisprocess in TTP.
Deficiency of ADAMTS13 leads to abnormally large multimers of a certain protein central to thisprocess in TTP. This process is inhibited by the protein ATIII. The tests INR and PTT are used to evaluatethe extrinsic and intrinsic arms of this process, respectively. This process is regulated by proteins C and S;the former protein no longer cleaves a certain other protein that has undergone a mutation named for thecity of Leiden. Several proteins involved in this process require a cofactor in order to be carboxylated atglutamic acid residues; that cofactor is Vitamin K. One of the first steps in this process is the formation offibrin from fibrinogen by thrombin. For 10 points, identify this process that commences by creating a plugof platelets
Deficiency of ADAMTS13 leads to abnormally large multimers of a certain protein central to thisprocess in TTP.
 blood clotting [or blood coagulation cascade; prompt on thrombogenesis; prompt on hemostasis]