One isoform of this protein is targeted by autoantibodies in Goodpasture's syndrome, and onemutation in this protein causes characteristic blue sclera.
One isoform of this protein is targeted by autoantibodies in Goodpasture's syndrome, and onemutation in this protein causes characteristic blue sclera. ADAMTS2 cleaves its precursors, which iswhy ADAMTS2 mutation causes EhlersÂ–Danlos syndrome. This protein is glycosylated withtwo-sugar units, and its lysine residues are crosslinked after secretion. Hydroxylysine andhydroxyproline are unique amino acids found in this molecule, whose synthesis requires (*) vitaminC. This protein contains glycine at almost every third residue, which allows it to form a compact triplehelix. This protein binds to integrins and fibronectins in the extracellular matrix, and gives tissues its tensilestrength. For 10 points, name this fibrous protein found in gelatin.
One isoform of this protein is targeted by autoantibodies in Goodpasture's syndrome, and onemutation in this protein causes characteristic blue sclera.
collagen