One example of this type of reaction forms a namesake thiohydroxamate ester, then treats it with tributyltin hydride, then uses a free radical process to cleave the ester--
One example of this type of reaction forms a namesake thiohydroxamate ester, then treats it with tributyltin hydride, then uses a free radical process to cleave the ester--that is the Barton reaction. Another free radical process for this type of reaction is initiated by the addition of bromine and ultimately forms an alkyl halide--that is the Hunsdiecker reaction. Biological examples of this type of reaction include the conversion of 5-HT to serotonin, and the conversion of L-DOPA to dopamine, and it also occurs in the formation of acetyl-CoA from pyruvate. Malonic acid and carbonic acid derivatives readily undergo this type of reaction. This type of reaction typically occurs via the heating of a beta-ketoacid, which spontaneously undergoes a pericyclic rearrangement into an enol, losing one carbon in the process. For 10 points, name this type of reaction that removes carboxylic acids from a molecule, releasing one molecule of carbon dioxide.
One example of this type of reaction forms a namesake thiohydroxamate ester, then treats it with tributyltin hydride, then uses a free radical process to cleave the ester--
decarboxylation