At the beginning of this process, there is a sharp separation between RAN guanosine [GWAN-oh-seen]  triphosphate [try-FAHS-fayt] and RAN guanosine diphosphate.
At the beginning of this process, there is a sharp separation between RAN guanosine [GWAN-oh-seen]  triphosphate [try-FAHS-fayt] and RAN guanosine diphosphate. Towards the end of this phase, Polo-like kinase  [KYNE-ase], sometimes with Aurora B, causes cohesin [co-HEE-sin] to separate from chromosomes as part of its namesake pathway. In this stage of mitosis the nucleolus disappears, and once condensin causes chromatin  condensation, the chromatin becomes visible. This phase leads to prometaphase [pro-MEH-tuh-fayz], which in turn leads to metaphase, and it follows the second gap of interphase. Name this first stage of mitosis.
At the beginning of this process, there is a sharp separation between RAN guanosine [GWAN-oh-seen]  triphosphate [try-FAHS-fayt] and RAN guanosine diphosphate.
{prophase} [prompt on mitosis before “pathway”; do not accept “prophase I” or “prophase II”]