One of these is the antigen of Anti Scl-70 and several inhibitors of them are found in genus Camptotheca, such as irinotecan and topotecan.
One of these is the antigen of Anti Scl-70 and several inhibitors of them are found in genus Camptotheca, such as irinotecan and topotecan. Their mechanism involves the formation of a protein bridge and these enzymes discovered by Wang are able to catenate circular DNA. Type II, which requires ATP hydrolysis, changes the linking number in steps of two. Gyrase is a special bacterial form of, for 10 points, what class of enzymes that reduce breaking and supercoliling by introducing single or double stranded breaks into DNA.
One of these is the antigen of Anti Scl-70 and several inhibitors of them are found in genus Camptotheca, such as irinotecan and topotecan.
{topoisomerase}s