Melanie Sanford's group has shown that this sort of reaction can be accomplished at room temperature under visible light using acyloxy-phthalimide initiators.
Melanie Sanford's group has shown that this sort of reaction can be accomplished at room temperature under visible light using acyloxy-phthalimide initiators. The coupling discovered by Murai and Kakiuchi is a classic example of these reactions. Bis-pinacol-borane substituted on rhodium or ruthenium is a common catalyst for this type of reaction. Amines or imines are used as innate directors in directed ortho metalation, an example of this type of reaction. Shilov showed that a mix of potassium hexa-chloro-platinate mixed with potassium tetra-chloro-platinate can be used to accomplish this task, for example, to (*) oxidize Zeise's salt. This process is accomplished by oxidative addition or sigma-bond metathesis, and an example of it would be turning ethane into ethanol. For 10 points, name this type of reaction in which a nonpolar bond found in all alkanes is cleaved and replaced by a reactive group.
Melanie Sanford's group has shown that this sort of reaction can be accomplished at room temperature under visible light using acyloxy-phthalimide initiators.
C-H activation [or carbon-hydrogen bond activation; or C-H functionalization; or other synonyms of the word activation that mention both carbon and hydrogen or C and H; prompt on borylation; prompt on amination; prompt on carbon-carbon bond formation; prompt on directed ortho metalation or DOM]