This protein's F57I and W64R mutants are associated with familial renal amyloidosis.
This protein's F57I and W64R mutants are associated with familial renal amyloidosis. The mechanism ofthis enzyme was solved by Volcado et al using bi-fluorinated substrates, which determined that this enzymeuses an SN2 reaction to displace its second product. The active site of this enzyme contains glutamate-35and asparagine-52, and the mechanism of this enzyme was originally posited to have a glycosyl carbocationintermediate by David (*) Phillips. Structural studies of this enzyme often use its hen's egg white variety. Thisenzyme breaks the beta-one-four linkages between N-acetylglucosamine and N-acetylmuramic acid found inpeptidoglycan, and like penicillin was originally discovered by Alexander Fleming. For 10 points, name this enzymefound in milk, saliva, and tears, which breaks down bacterial cell walls.
This protein's F57I and W64R mutants are associated with familial renal amyloidosis.
lysozyme