A 22q11 deletion or DISC1 disruption can predispose individuals to this disorder, which was once called dementia praecox.
A 22q11 deletion or DISC1 disruption can predispose individuals to this disorder, which was once called dementia praecox. Those affected lack smooth pursuit and exhibit poor mental flexibility to shifting patterns on the Wisconsin Card Sorting Test. It's not autism, but the "refrigerator mother" is a debunked theory of its occurrence. Haldol, Thorazine, and clozapine are commonly used to treat this disorder, which can manifest negative symptoms, such as flat affect and waxy flexibility, and positive symptoms, such as delusions and hallucinations. For 10 points, name this disorder with catatonic and paranoid types, which misleadingly means "split mind" in Greek. 
A 22q11 deletion or DISC1 disruption can predispose individuals to this disorder, which was once called dementia praecox.
schizophrenia 