Mutations in the gene cx43, which codes for their structural components, is associated with situs ambiguus, and mutations in cx32 cause Charcot-Marie- Tooth disease in which they do not function in myelin-forming cells.
Mutations in the gene cx43, which codes for their structural components, is associated with situs ambiguus, and mutations in cx32 cause Charcot-Marie- Tooth disease in which they do not function in myelin-forming cells. A sudden increase of calcium ion concentration (*) or a drop in pH causes their components' tilt angles to change, closing them and preventing the breakdown of osmotic balance. Also known as "electrical synapses," they serve a role similar to that of a plant cell's plasmodesmata by allowing a free flow of ions but disallowing passage of macromolecules heavier than one kilodalton. FTP name these collections of connexons, cylindrical channels two nanometers in diameter which connect the membranes of adjacent animal cells.
Mutations in the gene cx43, which codes for their structural components, is associated with situs ambiguus, and mutations in cx32 cause Charcot-Marie- Tooth disease in which they do not function in myelin-forming cells.
{gap} junctions