This process is stopped by the 911 complex, and it is prevented from repeating itself via binding of geminin.
This process is stopped by the 911 complex, and it is prevented from repeating itself via binding of geminin. CAF1 and ASF1 are chaperone proteins key to coordinating nucleosome deposition during this process. One key enzyme in this process is assisted by a trimer of PCNA proteins, which forms a sliding clamp. Sites in which this process will initiate bind to a hexamer of MCM proteins, and are known as origins. Flap endonucleases remove the primers used in this process, whose strict directionality requires the formation of Okazaki fragments on the lagging strand. This process is initiated by the action of helicase, which forms a bubble in which polymerase synthesizes a new strand from 5-prime to 3-prime. For 10 points, name this semiconservative process in which a cell's genome is copied.
This process is stopped by the 911 complex, and it is prevented from repeating itself via binding of geminin.
DNA replication [prompt on S phase, prompt on the cell cycle]