It has been used to explain a case of diastrophic displasia in Finland as well as deafness in families living on Martha's Vineyard.
It has been used to explain a case of diastrophic displasia in Finland as well as deafness in families living on Martha's Vineyard. One result of it is linkage disequilibrium, as it accounts for the unusual rate of Huntington's Disease in Afrikaaners and native people in the Lake Maracaibo region. A more famous case involving it is Ellis-van Creveld syndrome among the Amish, which has been traced back to Samuel King's 1744 settling of Eastern Pennsylvania. This concept was predated by the Sewall Wright's shifting balance theory, though its modern formulation appeared in Systematics and the Origin of Species by Ernst Mayr.  FTP, name this effect in which the establishment of a colony by a small number of individuals leads to a decrease in genetic variation.
It has been used to explain a case of diastrophic displasia in Finland as well as deafness in families living on Martha's Vineyard.
the {founder} effect (prompt on “bottleneck”)