One of these compounds can be formed through the use of HATU and Hünig's base. Synthesis of these compounds can be made more efficient with the use of triazoles to prevent racemization. RAM, also known as Rink resins are used to support these compounds. A compound of this type containing a methyl and methoxy substituent can react with organometallics to form ketones without overaddition. (*) Carbo·di·imides and PyBOP are commonly used to couple these compounds. Cyclic examples of these compounds will form when an oxime is placed in acidic conditions. When preparing one of these compounds, Fmoc and boc can be used as protecting groups. A cyclic example of this functional group is found in the class of antibiotics that includes penicillin. Those cyclic examples of these compounds are lactams, while these compounds are formed in the Merrifield synthesis. These compounds form from the hydrolysis of nitriles or the reaction of acyl chlorides with amines. For 10 points, name these compounds, which contain a carbonyl next to an amine.
One of these compounds can be formed through the use of HATU and Hünig's base. Synthesis of these compounds can be made more efficient with the use of triazoles to prevent racemization. RAM, also known as Rink resins are used to support these compounds. A compound of this type containing a methyl and methoxy substituent can react with organometallics to form ketones without overaddition. (*) Carbo·di·imides and PyBOP are commonly used to couple these compounds. Cyclic examples of these compounds will form when an oxime is placed in acidic conditions. When preparing one of these compounds, Fmoc and boc can be used as protecting groups. A cyclic example of this functional group is found in the class of antibiotics that includes penicillin. Those cyclic examples of these compounds are lactams, while these compounds are formed in the Merrifield synthesis. These compounds form from the hydrolysis of nitriles or the reaction of acyl chlorides with amines. For 10 points, name these compounds, which contain a carbonyl next to an amine.
One of these compounds can be formed through the use of HATU and Hünig's base.