This condition's association with sclerosing adenosis is controversial. Levels of CA15-3 in serum are used as a biomarker to detect and monitor the progression of this condition. One drug used to treat this condition is conjugated to the cytotoxic drug DM1 in its ";emtansine"; formulation. ";Targetoid"; and ";Indian file"; cell patterns are observed histologically in one form of this condition. Pressure on Cooper's ligament often causes an ";orange peel"; appearance in an aggressive form of this condition. This condition can be treated by SERMs like tamoxifen or by HER
This condition's association with sclerosing adenosis is controversial. Levels of CA15-3 in serum are used as a biomarker to detect and monitor the progression of this condition. One drug used to treat this condition is conjugated to the cytotoxic drug DM1 in its ";emtansine"; formulation. ";Targetoid"; and ";Indian file"; cell patterns are observed histologically in one form of this condition. Pressure on Cooper's ligament often causes an ";orange peel"; appearance in an aggressive form of this condition. This condition can be treated by SERMs like tamoxifen or by HER2/neu monoclonal antibodies such as Herceptin. About ten percent of patients with this condition have its difficult-to-treat ";triple negative"; form, because they test negative for ErbB2, progesterone, and estrogen receptors. This condition is divided into ";ductal"; and ";lobular"; subtypes. The genes BRCA1 and BRCA2 are correlated with development of, for 10 points, what condition treated by a mastectomy?
This condition's association with sclerosing adenosis is controversial.