This class of drugs, as well as methylxanthines like caffeine, should be avoided by individuals with glucose transporter type I deficiency syndrome. The compound that is the namesake of this class of drugs is hydrolyzed and its ring opened in the second step of oxidative pyrimidine degradation, is involved in riboflavin synthesis, and forms other members of this class of compounds through the Knoevenagel condensation; that compound can be formed by a reaction between malonic acid and urea. This class of compounds increase the number of glycogen granules in astrocytes. Drugs in this class include the long-acting anticonvulsant phenobarbital and a compound that finds its major therapeutic use as an ultrashort anaesthetic but is better known as a truth serum drug, sodium thiopental. This class of drugs, which blocks the glutamate receptor AMPA, also increases the frequency of chloride channel opening when it binds to the alpha subunit of the GABAA receptor. For 10 points, name this class of central nervous system
This class of drugs, as well as methylxanthines like caffeine, should be avoided by individuals with glucose transporter type I deficiency syndrome. The compound that is the namesake of this class of drugs is hydrolyzed and its ring opened in the second step of oxidative pyrimidine degradation, is involved in riboflavin synthesis, and forms other members of this class of compounds through the Knoevenagel condensation; that compound can be formed by a reaction between malonic acid and urea. This class of compounds increase the number of glycogen granules in astrocytes. Drugs in this class include the long-acting anticonvulsant phenobarbital and a compound that finds its major therapeutic use as an ultrashort anaesthetic but is better known as a truth serum drug, sodium thiopental. This class of drugs, which blocks the glutamate receptor AMPA, also increases the frequency of chloride channel opening when it binds to the alpha subunit of the GABAA receptor. For 10 points, name this class of central nervous system depressant drugs.
This class of drugs, as well as methylxanthines like caffeine, should be avoided by individuals with glucose transporter type I deficiency syndrome.
{barbiturates}