In vitro, a deficiency of this compound causes reduced acetylcholine synthesis.  In the body it requires lipoic acid for the reactions which it participates in, thus people with liver disease show a deficiency in this vitamin.  It serves as a coenzyme for the decarboxylation of pyruvate and the oxidation of alpha keto-glutamic acid.  The coenzyme for its namesake pyrophosphatase, FTP, identify this vitamin, a lack of which can cause beriberi.
In vitro, a deficiency of this compound causes reduced acetylcholine synthesis.  In the body it requires lipoic acid for the reactions which it participates in, thus people with liver disease show a deficiency in this vitamin.  It serves as a coenzyme for the decarboxylation of pyruvate and the oxidation of alpha keto-glutamic acid.  The coenzyme for its namesake pyrophosphatase, FTP, identify this vitamin, a lack of which can cause beriberi.
In vitro, a deficiency of this compound causes reduced acetylcholine synthesis.  
vitamin B1 or thiamine