Dicumarol, a coumarin derivative, inhibits this process by blocking the VKORC enzyme, thereby preventing proper carboxylation of proteins involved in it. Warfarins prevent this process in a similar feedback system, and it involves a certain factor that binds to exposed colla
Dicumarol, a coumarin derivative, inhibits this process by blocking the VKORC enzyme, thereby preventing proper carboxylation of proteins involved in it. Warfarins prevent this process in a similar feedback system, and it involves a certain factor that binds to exposed collagen in endothelial cells. That von Willebrand factor is deficient in the same-named disease characterized by an abnormality in this process. One of its initiating factors is thrombin, which converts fibrinogen into fibrin to form a thrombus. This process is characterized by fibrin polymerization to form a mesh-like framework together with platelets at the site of a wound. For 10 points, identify this deficiency of hemophiliacs, the process by which blood clots.
Dicumarol, a coumarin derivative, inhibits this process by blocking the VKORC enzyme, thereby preventing proper carboxylation of proteins involved in it.
 coagulation [or thrombosis; or clotting before mentioned]