These structures resolve a problem first recognized by Alexei Olovnikov, although they are not necessary in most bacteriophages and bacteria. Their namesake enzyme was first discovered in Tetrahymena. That enzyme is a ribonucleoprotein which carries out reverse transcription to add several repeats of a six-nucleotide sequence, (*) TTAGGG. Hydrogen bonding between those guanine residues creates a hairpin structure, which enables the rest of the lagging strand to be filled in. Although they are extremely stable in most tumor cells, these structur
These structures resolve a problem first recognized by Alexei Olovnikov, although they are not necessary in most bacteriophages and bacteria. Their namesake enzyme was first discovered in Tetrahymena. That enzyme is a ribonucleoprotein which carries out reverse transcription to add several repeats of a six-nucleotide sequence, (*) TTAGGG. Hydrogen bonding between those guanine residues creates a hairpin structure, which enables the rest of the lagging strand to be filled in. Although they are extremely stable in most tumor cells, these structures gradually shorten as a normal somatic cell ages. For 10 points, name these segments of DNA which protect the ends of linear chromosomes from decay.
These structures resolve a problem first recognized by Alexei Olovnikov, although they are not necessary in most bacteriophages and bacteria.
{telomeres}