Some aminoglycoside antibiotics, such as kanamycin, inhibit the activity of
Some aminoglycoside antibiotics, such as kanamycin, inhibit the activity of these structures. The binding of certain molecules to their A-sites is facilitated by elongation factors; those molecules are later shifted to the E-site for removal. In bacteria, they recognize and bind to purine-only segments upstream of f-met called (*) Shine-Dalgarno sequences. The prokaryotic versions of these structures are composed of two subunits, 30S and 50S. They may be free-floating in the cytosol or membrane-bound within the endoplasmic reticulum, and they name the type of RNA most abundant in the cell. For 10 points, identify these tiny structures synthesized in the nucleolus, which produce polypeptide chains in translation.
Some aminoglycoside antibiotics, such as kanamycin, inhibit the activity of these structures.
ribosomes