An ester modification of these is the Fries rearrangement, and it was first published in Comptes rendus in 1884. One form of them is strongly inhibited by the presence of electron acceptors and carbocation rearrangement decreases its useful yield. The reactivity of one of their constituents increases with the polarity of the C-X bond. Both forms ar
An ester modification of these is the Fries rearrangement, and it was first published in Comptes rendus in 1884. One form of them is strongly inhibited by the presence of electron acceptors and carbocation rearrangement decreases its useful yield. The reactivity of one of their constituents increases with the polarity of the C-X bond. Both forms are limited to fairly reactive arenas and use a Lewis acid catalyst, typically aluminum tri-chloride. FTP, identify these electrophilic aromatic substitutions that synthesize either an acyl or an alkyl from benzene, named for their French and American discoverers.
An ester modification of these is the Fries rearrangement, and it was first published in Comptes rendus in 1884.
Friedel-Crafts reactions