Infection with an anaerobic gram-positive rod causes this disease, which is
Infection with an anaerobic gram-positive rod causes this disease, which is mediated by a plasmid-produced toxin. The toxin that causes the symptoms of this disease is absorbed by peripheral nerves and is transported to the brainstem and spinal cord, where it binds to specific presynaptic nerve terminals.  That prevents the release of glycine and GABA, leading to the increased firing rate of alpha motor neurons.  Cardinal signs of this disease include a sustained grimace or sneer, arched back, and difficulty swallowing. Typically beginning with spasms of the masseter muscle, FTP, name this bacterial disease, uncommon in the US due to vaccination, which can be acquired by stepping on a rusty nail.
Infection with an anaerobic gram-positive rod causes this disease, which is mediated by a plasmid-produced toxin.
tetanus or Clostridium tetani or trismus or lockjaw