Infant dactylitis, or swelling of one or more digits, is an early sign of this disease. Prophylactic penicillin and hydroxyurea are used to treat it, and people with this disease often suffer splenic infarction and subsequently have the spleen removed. A point mutation that leads to this disease causes a sixth-residue (*) glutamine to change to a valine. Possessing one allele with this disease's causative mutation confers resistance to malaria. The aggregation of the beta-globin chains of hemogl
Infant dactylitis, or swelling of one or more digits, is an early sign of this disease. Prophylactic penicillin and hydroxyurea are used to treat it, and people with this disease often suffer splenic infarction and subsequently have the spleen removed. A point mutation that leads to this disease causes a sixth-residue (*) glutamine to change to a valine. Possessing one allele with this disease's causative mutation confers resistance to malaria. The aggregation of the beta-globin chains of hemoglobin blocks blood vessels and leads to this disease's namesake "crises." For 10 points, name this disease most common in people of African descent that causes blood cells to form a namesake abnormal curved shape.
Infant dactylitis, or swelling of one or more digits, is an early sign of this disease.
{sickle cell} anemia