This class of molecules shares its name with a protein that associates with BiP and calnexin in the endoplasmic reticulum after being produced in the secretory pathway of the vesicular stomatitis virus. One protein in this class induces membrane ruffles upon injection into fibroblasts, and another mimics the effects of the chemokine LPA. In another one, replacement of the glycine at position 12 keeps it in the active state, leading to uncontrolled cell growth. Effectors associated with this class include adenylyl cyclase and phospholipase C, and the trimeric form breaks into a beta-gamma dimer and an alpha subunit, which activates a second messenger to begin a signal transduction cascade. For 10 points, name this cl
This class of molecules shares its name with a protein that associates with BiP and calnexin in the endoplasmic reticulum after being produced in the secretory pathway of the vesicular stomatitis virus. One protein in this class induces membrane ruffles upon injection into fibroblasts, and another mimics the effects of the chemokine LPA. In another one, replacement of the glycine at position 12 keeps it in the active state, leading to uncontrolled cell growth. Effectors associated with this class include adenylyl cyclase and phospholipase C, and the trimeric form breaks into a beta-gamma dimer and an alpha subunit, which activates a second messenger to begin a signal transduction cascade. For 10 points, name this class of proteins, monomeric forms of which include Rac and Ras, which, when active, hydrolyze guanosine triphosphate.
This class of molecules shares its name with a protein that associates with BiP and calnexin in the endoplasmic reticulum after being produced in the secretory pathway of the vesicular stomatitis virus.
G proteins [accept early GTPase switch proteins]