The major structural proteins of these entities use the PTAP motif to recruit the ESCRT-1 ["escort-one"] complex and the LYPxL motif to recruit the ALIX protein in order to facilitate the budding proc
The major structural proteins of these entities use the PTAP motif to recruit the ESCRT-1 ["escort-one"] complex and the LYPxL motif to recruit the ALIX protein in order to facilitate the budding process. In addition to possessing the Gag polyprotein, these entities produce the Vif protein which counteracts the effects of the cytidine deaminase APOBEC3G. They are unable to infect individuals who possess a homozygous 32 base pair deletion in the CCR5 protein. The glycoprotein gp120 found on them allows them to dock onto CD4 receptors, and azidothymidine is a reverse transcriptase inhibitor that is used to treat infections by this agent. For 10 points, name this retrovirus that mostly infects immune cells and which causes AIDS.
The major structural proteins of these entities use the PTAP motif to recruit the ESCRT-1 ["escort-one"] complex and the LYPxL motif to recruit the ALIX protein in order to facilitate the budding process.
 HIV [or human immunodeficiency virus]