These compounds react with an alpha-bromoester and zinc metal to form a beta-ketoester in the Blaise reaction. One of them reacts with an arene to give an aryl ketone in a rea
These compounds react with an alpha-bromoester and zinc metal to form a beta-ketoester in the Blaise reaction. One of them reacts with an arene to give an aryl ketone in a reaction similar to the Friedel-Crafts acylation, called the Hoesch reaction. These non-ester functional groups produce a strong peak at 2250 inverse centimeters in an IR spectrum and can be reduced to aldehydes by DIBAL-H. They are hydrolyzed to form (*) amino acids in the second step of the Strecker synthesis. A polymer of this functional group forms a synthetic rubber commonly used in laboratory gloves. In a reaction named for Kolbe, these compounds are produced by reducing primary amides or by reacting alkyl halides with hydrogen cyanide. For 10 points name this functional group containing a carbon triple bonded to nitrogen.
These compounds react with an alpha-bromoester and zinc metal to form a beta-ketoester in the Blaise reaction.