The extreme nephrotoxicity of one of these drugs is mitigated somewhat by its two FDA-approved liposomal delivery systems. Tubulin is the target of a drug of this type named griseofulvin. One of these drugs uses a non-human cytosine deaminase enzyme to transform the inactive form, flucytosine, into the active 5-fluorouracil. Glucan synthesis is inhibited by a class of these drugs called echinocandins. Squalene epoxidase is targeted by some of these drugs, such as naftifi
The extreme nephrotoxicity of one of these drugs is mitigated somewhat by its two FDA-approved liposomal delivery systems. Tubulin is the target of a drug of this type named griseofulvin. One of these drugs uses a non-human cytosine deaminase enzyme to transform the inactive form, flucytosine, into the active 5-fluorouracil. Glucan synthesis is inhibited by a class of these drugs called echinocandins. Squalene epoxidase is targeted by some of these drugs, such as naftifine and butenafine. One class of these medications inhibits the enzyme lanosterol 14-alpha demethylase, preventing the production of (*) ergosterol. Multiple double bonds are present in the polyene class of these drugs, including amphotericin B, and other classes of them include imidazoles and triazoles. A drug of this type named clotrimazole is often topically applied to treat Candida albicans-caused vulvovaginitis. For 10 points, name this class of medications which can be used against oral thrush, athlete's foot, and other diseases caused by a non-bacterial kingdom of organisms.
The extreme nephrotoxicity of one of these drugs is mitigated somewhat by its two FDA-approved liposomal delivery systems.