One reaction forms these compounds by reacting a carboxylic acid with hydrazoic acid in the presence of a protic catalyst. In another reaction, this functionality is added beta to a carbonyl carbon with the assistance of an activated formaldehyde molecule. Those are the Schmidt and Mannich reactions. Carbonyls are converted to an intermediate that is reduced to these compounds using sodium cyanobo
One reaction forms these compounds by reacting a carboxylic acid with hydrazoic acid in the presence of a protic catalyst. In another reaction, this functionality is added beta to a carbonyl carbon with the assistance of an activated formaldehyde molecule. Those are the Schmidt and Mannich reactions. Carbonyls are converted to an intermediate that is reduced to these compounds using sodium cyanoborohydride in their namesake (*) "reductive" synthesis. The application of silver oxide, water, and heat removes this functional group and leaves behind an alkene in the Hofmann elimination. These compounds, which can be synthesized via the Gabriel synthesis, often have a fishy smell. For 10 points, name these compounds that contain one or more alkyl or aryl groups around a basic nitrogen atom.
One reaction forms these compounds by reacting a carboxylic acid with hydrazoic acid in the presence of a protic catalyst.