Increasing the concentration of an indicator in the presence of one of these substances creates a series of parallel lines on a Cornish-Bowden plot. They modify K sub m by multiplying by the factor alpha, which is equal to one plus the quantity their concentration divided by their dissociation constant. These substances do not affect the activity of their target and do not bind to the ES complex. Increasing the concentration of one of these substances decreases the x-intercept, but keeps the y-intercept constant, on a Lineweaver-Burke plot. They do not affect the V-max
Increasing the concentration of an indicator in the presence of one of these substances creates a series of parallel lines on a Cornish-Bowden plot. They modify K sub m by multiplying by the factor alpha, which is equal to one plus the quantity their concentration divided by their dissociation constant. These substances do not affect the activity of their target and do not bind to the ES complex. Increasing the concentration of one of these substances decreases the x-intercept, but keeps the y-intercept constant, on a Lineweaver-Burke plot. They do not affect the V-max of their target at a given concentration, because increasing the reactant concentration floods them out. This type of inhibitor typically binds to the active site and serves to block the binding of the substrate. For 10 points, name this type of enzyme inhibitor distinct from an uncompetitive or non-competitive inhibitor.
Increasing the concentration of an indicator in the presence of one of these substances creates a series of parallel lines on a Cornish-Bowden plot.