When these organelles cannot receive mannose-marked proteins, inclusion-cell disease occurs. The improper metabolism of sphingolipids in these organelles causes Gaucher's disease. Another disease associated with this organelle is caused when hexosaminidase A is not produced at high enough levels, and is called Tay-Sachs disease. These organelles are responsible for a type of programmed cell death 
When these organelles cannot receive mannose-marked proteins, inclusion-cell disease occurs. The improper metabolism of sphingolipids in these organelles causes Gaucher's disease. Another disease associated with this organelle is caused when hexosaminidase A is not produced at high enough levels, and is called Tay-Sachs disease. These organelles are responsible for a type of programmed cell death called autophagy, and they utilize hydrolases and proteases. For 10 points, name these digestive organelles whose function is to break down cellular waste.
When these organelles cannot receive mannose-marked proteins, inclusion-cell disease occurs.