One protein that interacts with this complex does so via an IBB domain. The "selective phase model" of this complex's operation was lent credence when Frey and Gorlich created a model of them by injecting peptides into a hydr
One protein that interacts with this complex does so via an IBB domain. The "selective phase model" of this complex's operation was lent credence when Frey and Gorlich created a model of them by injecting peptides into a hydrogel. Another model of these structures states that receptors undergo a two-dimensional random walk through a disordered mesh of phenylalanine-glycine repeats and is known as the reduction of dimensionality model. These complexes contain around 500 proteins, many with alpha-solenoid and beta-propeller folds. They use a gradient of Ran-GTP in order to perform their most notable function. Molecules with weight less than 30 kilodaltons are able to diffuse through them, though their function usually requires a heavily basic localization signal which binds to importin-alpha. The membrane containing them is held together by lamins. For 10 points, name these protein complexes that move things into and out of the nucleus.
One protein that interacts with this complex does so via an IBB domain.