This organism dodges the immune system by expressing Lewis blood group antigens, and the most common strains are J99 and 26685. Virulent strains encode a toxin that binds to VIP54 and creates large vacuoles, known as VacA. They encode a Type IV secretory system in the CagA pathogenicity island, whic
This organism dodges the immune system by expressing Lewis blood group antigens, and the most common strains are J99 and 26685. Virulent strains encode a toxin that binds to VIP54 and creates large vacuoles, known as VacA. They encode a Type IV secretory system in the CagA pathogenicity island, which also activates the SH2 kinase. A urease breath test can be used to detect this microaerophile, and the inflammatory response to it induces the secretion of gastrin from G cells. Treating infection with this organism involves two antibiotics and a proton pump inhibitor, and it was studied by Barry Marshall, who notably drank a solution of it to prove that it causes gastritis. For 10 points, name this bacterium responsible for many ulcers.
This organism dodges the immune system by expressing Lewis blood group antigens, and the most common strains are J99 and 26685.
{Helicobacter pylori}