Maryanoff and Reitz studied deviations from the proposed mechanism of this reaction, discovering a phenomenon they dubbed "stereochemical drift." One modification of this reaction uses phenyllithium and hydrochloric acid to c
Maryanoff and Reitz studied deviations from the proposed mechanism of this reaction, discovering a phenomenon they dubbed "stereochemical drift." One modification of this reaction uses phenyllithium and hydrochloric acid to convert an erthyro betaine into the threo variety. That modification allows the products of this reaction to be made in the E or trans form, while the normal variety can only create the Z or cis form. This reaction with a modification named after Schlosser has a phenylphosphine oxide byproduct which is created from a phosphonium ylide (ih-lid) reagent. Initiated by reacting an aldehyde or ketone with an ylide, for 10 points, identify this organic synthesis that is used to synthesize alkenes.
Maryanoff and Reitz studied deviations from the proposed mechanism of this reaction, discovering a phenomenon they dubbed "stereochemical drift.
{Wittig} Reaction