This model was generalized to two-product systems with any number of intermediates by Bloomfield, Peller, and Alberty. King and Altman laid the groundwork for Hill's diagram method for this model. It is extended into a two-state system by the Goldbeter-Koshland formula, and the Hill equation measures a factor that leads to deviations from this model. The Hanes-Woolf plot is an attempt to linearize this model, which invokes quasi-steady-state conditions set out by Briggs and Haldane. In other linearizations, the even weighting of the Eadie-Hofstee diagram is preferred to the uneven weights implicit in the double-recipr
This model was generalized to two-product systems with any number of intermediates by Bloomfield, Peller, and Alberty. King and Altman laid the groundwork for Hill's diagram method for this model. It is extended into a two-state system by the Goldbeter-Koshland formula, and the Hill equation measures a factor that leads to deviations from this model. The Hanes-Woolf plot is an attempt to linearize this model, which invokes quasi-steady-state conditions set out by Briggs and Haldane. In other linearizations, the even weighting of the Eadie-Hofstee diagram is preferred to the uneven weights implicit in the double-reciprocal Lineweaver-Burk plot. FTP, name this model which gives initial reaction rate as equal to maximum rate times substrate concentration over a constant plus substrate concentration.
This model was generalized to two-product systems with any number of intermediates by Bloomfield, Peller, and Alberty.
{Michaelis-Menten}-Henri kinetics