Reaction of naphthalenes with succinic anhydride to form phenanthrenes proceeds via this reaction followed by two reductions, a cyclization, and a dehydrogenation in the Haworth [HAY-worth] synthesis. Carbon monoxide and hydrochloric acid generate a reactive acyl chloride to formylate benzene in a variant of this reaction named for Gattermann and Koch. Possible rearrangements in one form of this reaction are avoided by us
Reaction of naphthalenes with succinic anhydride to form phenanthrenes proceeds via this reaction followed by two reductions, a cyclization, and a dehydrogenation in the Haworth [HAY-worth] synthesis. Carbon monoxide and hydrochloric acid generate a reactive acyl chloride to formylate benzene in a variant of this reaction named for Gattermann and Koch. Possible rearrangements in one form of this reaction are avoided by using the (*) Clemmensen reduction to reduce the acyl products of its other form. Deactivated rings like phenols cannot undergo this reaction. This reaction generally uses a Lewis acid catalyst like aluminum trichloride to alkylate or acylate aromatic compounds. For 10 points name this electrophilic aromatic substitution reaction named for a French and an American chemist.
Reaction of naphthalenes with succinic anhydride to form phenanthrenes proceeds via this reaction followed by two reductions, a cyclization, and a dehydrogenation in the Haworth [HAY-worth] synthesis.
Friedel–Crafts reaction [or Friedel–Crafts alkylation; or Friedel–Crafts acylation; accept Haworth synthesis until read; prompt on electrophilic aromatic substitution until read; prompt on alkylation or acylation] &lt;JL, Chem&gt;