A particularly bulky example of this functional group is found in Hunig's base. They're not hydroxyl groups, but the buffers Tris and HEPES contain this functional group. Aromatic examples of this functional group can be synthesized using the Buchwald-Hartwig cross-coupling 
A particularly bulky example of this functional group is found in Hunig's base. They're not hydroxyl groups, but the buffers Tris and HEPES contain this functional group. Aromatic examples of this functional group can be synthesized using the Buchwald-Hartwig cross-coupling reaction. One method of synthesizing these compounds reacts an alkyl halide with potassium phthalimide, then cleaves the product with hydrazine. This functional group undergoes exhaustive methylation in a reaction which produces the (*) less-substituted alkene; that elimination is named for Hofmann and violates Zaitsev's rule. The Gabriel synthesis produces this functional group, which has a pKa of around 36, though their protonated forms have pKa around 10. For 10 points, name this functional group which contains a nitrogen single bonded to one or more carbon chains
A particularly bulky example of this functional group is found in Hunig's base.
amine