The angiogenesis inhibitor endostatin is derived from the breakdown of this protein. The coppercontaining enzyme lysyl oxidase catalyzes the formation of aldehydes from the epsilon-amino group of lysines, allowing cross-linking of this protein. A form of this protein is defective in a disease that presents with blue sclera. Defects in it can result in EhlersDanlos syndrome, osteogenesis imperfecta, and (*) Alport's syndrome. The pro form of this protein is assembled in the ER, and peptidases cleave propetides at the ends of that pro form after secretion. It contains many glycine-proline-X and glycine-X-hydroxyproline motifs. Ascorbic acid is a cofactor in the synthesis of this protein, which possesses a triple-he
The angiogenesis inhibitor endostatin is derived from the breakdown of this protein. The coppercontaining enzyme lysyl oxidase catalyzes the formation of aldehydes from the epsilon-amino group of lysines, allowing cross-linking of this protein. A form of this protein is defective in a disease that presents with blue sclera. Defects in it can result in EhlersDanlos syndrome, osteogenesis imperfecta, and (*) Alport's syndrome. The pro form of this protein is assembled in the ER, and peptidases cleave propetides at the ends of that pro form after secretion. It contains many glycine-proline-X and glycine-X-hydroxyproline motifs. Ascorbic acid is a cofactor in the synthesis of this protein, which possesses a triple-helix structure. For 10 points, name this fibrous protein that comprises most of the extracellular matrix.
The angiogenesis inhibitor endostatin is derived from the breakdown of this protein.
collagen