These cells' surfaces contain homodimers of CD94 and CD159a as an activating receptor and they require the transcription factor NFIL3 for their development. A precursor of the
These cells' surfaces contain homodimers of CD94 and CD159a as an activating receptor and they require the transcription factor NFIL3 for their development. A precursor of these cells are RORC- and CD127-double-positive and control the organogenesis of lymph nodes; those are LTi cells. In the placenta, these cells are down-regulated by HLA-E, which is selectively expressed by trophoblasts. The mouse cytomegalovirus can invade these cells via the Ly49H receptor, and they express the surface receptors CD16 and CD56. These cells, which are an evolutionary bridge between the (*) adaptive and innate immune systems, do not require the presence of MHC class I in order to destroy their targets. These cells are responsible for attacking tumors and virus-infected cells, and like cytotoxic T cells have granules containing perforin and granzyme. For 10 points, name these immune cells named for their innate ability to attack non-self cells.
These cells' surfaces contain homodimers of CD94 and CD159a as an activating receptor and they require the transcription factor NFIL3 for their development.
Natural Killer cells or NK cells