This disease is the subject of the "dying-back" model, in which this disease spreads distal toproximal. The main drug used to treat this disease acts upon tetrodotoxin-sensitive sodium channelsin order to block stimulation of glutamate receptors; that drug is Riluzole. The G93A mutation insuperoxide dismutase 1 is a common cause of the familial form of this disease. The bulbar-onset formof this disease begins with dysarthria and difficulty (*) swallowing, though most patients suffer from itslimb-onset form. Victims of this disease usually die from pneumonia or respiratory failure after theintercostal muscles and diaphragm weaken, and For 10 points, name this neurodegenerative disease inwhich motor neurons atrophy, whose most famous sufferer
This disease is the subject of the "dying-back" model, in which this disease spreads distal toproximal. The main drug used to treat this disease acts upon tetrodotoxin-sensitive sodium channelsin order to block stimulation of glutamate receptors; that drug is Riluzole. The G93A mutation insuperoxide dismutase 1 is a common cause of the familial form of this disease. The bulbar-onset formof this disease begins with dysarthria and difficulty (*) swallowing, though most patients suffer from itslimb-onset form. Victims of this disease usually die from pneumonia or respiratory failure after theintercostal muscles and diaphragm weaken, and For 10 points, name this neurodegenerative disease inwhich motor neurons atrophy, whose most famous sufferer was Lou Gehrig.
This disease is the subject of the "dying-back" model, in which this disease spreads distal toproximal.
ALS [or Amyotrophic Lateral Sclerosis; accept Lou Gehrig's disease till mention]