This class of drugs contains a benizimidazole group linked to a pyridine, and these drugs all bind to cysteine 813 between TM
This class of drugs contains a benizimidazole group linked to a pyridine, and these drugs all bind to cysteine 813 between TM5 and TM6 of their target protein. A recent FDA warning states that long term use of these drugs may cause chronic low magnesium, and these drugs are known to decrease absorption of vitamin B12. These drugs, which have replaced H2 blockers like cimetidine, are used to treat Zollinger-Ellison syndrome. A triple therapy regimen with amoxicillin, clarithromycin, and one of these drugs is used to treat H. Pylori infections. These drugs target the parietal cell H/K ATPase, resulting in a decrease in acid production. For 10 points, identify this class of drugs which includes omeprazole, or Prilosec, where are used to treat ulcers and acid reflux disease.
This class of drugs contains a benizimidazole group linked to a pyridine, and these drugs all bind to cysteine 813 between TM5 and TM6 of their target protein.
Proton Pump inhibitors