One gene encoded by this virus has an H274Y mutation that renders it drug-resistant. An alternatereading frame of its PB1 gene encodes a protein that interacts with mitrochondrial pore components.The 
One gene encoded by this virus has an H274Y mutation that renders it drug-resistant. An alternatereading frame of its PB1 gene encodes a protein that interacts with mitrochondrial pore components.The uncoating of this virus requires the M2 channel, which is inhibited by amantadine. The genomeof this agent contains eight negative-sense RNA strands, which allows it to recombine and (*) jumpspecies during a co-infection. Its genome encodes a pair of surface proteins that bind to and cleave sialicacid, known as hemagglutinin and neuraminidase. This virus, which is targeted by zanamvir andoseltamivir, undergoes antigenic drift, resulting in a new strain every year. For 10 points, name thisorthomyxovirus that causes a yearly swath of cold-like illnesses.
One gene encoded by this virus has an H274Y mutation that renders it drug-resistant.
Influenza