Invitrogen's BLOCK-iT alg
Invitrogen's BLOCK-iT algorithm is used to design high-throughput screens using this process. Oneprotein used in this process was named for Arabidopsis mutants whose leaves looked like octopi. SID-1 encodes a channel necessary for this process in C. elegans, which uses this process to regulate lin-14via lin-4 during development. The aforementioned protein, Argonaute, makes up the catalytic subunitof (*) the RISC complex, which uses the small interfering molecules generated by DICER. This processresults in either inhibition of translation or degradation of the target messenger, leading to geneknockdown. For 10 points, name this process whereby single-stranded RNA is silenced thanks to therecognition of double-stranded RNA with the same sequence.
Invitrogen's BLOCK-iT algorithm is used to design high-throughput screens using this process.
RNA Interference [or RNAi]