A W897X mutation in the SCN9A sodium channel cause
A W897X mutation in the SCN9A sodium channel causes an inability to experience this phenomenon, which is carried by the tract of Lissauer. An initial form of this phenomenon is caused by activation of A-delta fibers. It's not themoreception, but information about this phenomenon is carried via the spinothalamic and trigeminal pathways, and it is depleted via selective prolonged activation of TRPV1 binding via capsaicin. This sensation is carried by small, unmyelinated C- fibers. A "referred" form of this phenomenon occurs after insufficient oygen reception at the heart, in the form of angina. For 10 points, identify this somatic sensation which is suppressed by endogenous opiates which produce strong analgesia.
A W897X mutation in the SCN9A sodium channel causes an inability to experience this phenomenon, which is carried by the tract of Lissauer.
nociception [accept pain or experiencing pain]