One model of this area proposes that its proteins evolve rapidly to suppress the deleterious effectsof its namesake drive, such as skewed sex ratios. A specific type of this area is required forRobertsonian fusions. The classical neo- type of this structure can form heterochromatic "knobs" inmaize, and adding a telomere to a broken end or inactivating one of these can end thebreakage/fusion/bridge cycle. In these, HJURP acts as a chaperone for one of their (*) histone H3variants, CENP-A, which differentiates it from its surroundings. It assembles the kinetochore, thusbecoming the site of spindle attachment to chromosomes at mitosis and meiosis. For 10 points, name thisregion of DNA that separates the p and q arms of
One model of this area proposes that its proteins evolve rapidly to suppress the deleterious effectsof its namesake drive, such as skewed sex ratios. A specific type of this area is required forRobertsonian fusions. The classical neo- type of this structure can form heterochromatic "knobs" inmaize, and adding a telomere to a broken end or inactivating one of these can end thebreakage/fusion/bridge cycle. In these, HJURP acts as a chaperone for one of their (*) histone H3variants, CENP-A, which differentiates it from its surroundings. It assembles the kinetochore, thusbecoming the site of spindle attachment to chromosomes at mitosis and meiosis. For 10 points, name thisregion of DNA that separates the p and q arms of chromosomes.
One model of this area proposes that its proteins evolve rapidly to suppress the deleterious effectsof its namesake drive, such as skewed sex ratios.
centromeres [do not accept "centrosome" or "kinetochore"]