Ivermectin inhibits glutamate-gated channels that conduct this ion, and mutations in anotherchannel that conduct it cause myotonia congenita. Because this ion has an equilibrium potential closeto negative 65 millivolts, it causes shunting inhibition in neurons. Via G-protein hyperactivation,cholera toxin causes diarrhea by driving the (*) efflux of this ion. A co-transporter that moves two ofthis ion, along with sodium and potassium, is inhibited by loop diuretics. Another channel that conductsboth this ion and thiocyanate is stuck to the cytos
Ivermectin inhibits glutamate-gated channels that conduct this ion, and mutations in anotherchannel that conduct it cause myotonia congenita. Because this ion has an equilibrium potential closeto negative 65 millivolts, it causes shunting inhibition in neurons. Via G-protein hyperactivation,cholera toxin causes diarrhea by driving the (*) efflux of this ion. A co-transporter that moves two ofthis ion, along with sodium and potassium, is inhibited by loop diuretics. Another channel that conductsboth this ion and thiocyanate is stuck to the cytoskeleton by a PDZ domain, and a deletion atphenylalanine-508 of that protein causes cystic fibrosis. For 10 points, name this anion, the predominantnegatively-charged species in both the cytosol and extracellular fluid.
Ivermectin inhibits glutamate-gated channels that conduct this ion, and mutations in anotherchannel that conduct it cause myotonia congenita.
chloride [or Cl-]