Sufferers of this disease classically use the Gowers maneuver. It is caused by a mutation in aprotein that colocalizes with syncolin and synemin in the DGC complex. Patients with this diseasehave over ten times the normal amount of CPK. The protein mutated in this disease contains 79exons and is responsible for coupling the basal lamina to the cytoskeleton, and traverses the (*)sarcolemma. Patients with this disease develop cardiomyopathy around age 20 and wheelchair- andventilator-dependence by age 13. This disease, which is a more severe form of a disease named for B
Sufferers of this disease classically use the Gowers maneuver. It is caused by a mutation in aprotein that colocalizes with syncolin and synemin in the DGC complex. Patients with this diseasehave over ten times the normal amount of CPK. The protein mutated in this disease contains 79exons and is responsible for coupling the basal lamina to the cytoskeleton, and traverses the (*)sarcolemma. Patients with this disease develop cardiomyopathy around age 20 and wheelchair- andventilator-dependence by age 13. This disease, which is a more severe form of a disease named for Becker,is caused by very large deletions of a protein encoded by the X chromosome. For 10 points, name thisgenetic disease which causes progressive muscle weakness.
Sufferers of this disease classically use the Gowers maneuver.
Duchenne Muscular Dystrophy [or Duchenne MD]