This structure is absent in the "complete" DiGeorge's syndrome, though it is merely afflicted with aplasia in normal DiGeorge'ssyndrome. APECED patients suffer from mutations in the AIRE gene, which is normally expressed only in the medullaof this structure. It's not the brain, but the barrier between this structure and the bloodstream is maintained by epithelial cellsknown as "nurse cells." It consists of a 3D network of meshes formed by interconnected, Âfinely-branched epithelial reticularcells. Surgical removal of this structure is a drasticway to force remission
This structure is absent in the "complete" DiGeorge's syndrome, though it is merely afflicted with aplasia in normal DiGeorge'ssyndrome. APECED patients suffer from mutations in the AIRE gene, which is normally expressed only in the medullaof this structure. It's not the brain, but the barrier between this structure and the bloodstream is maintained by epithelial cellsknown as "nurse cells." It consists of a 3D network of meshes formed by interconnected, Âfinely-branched epithelial reticularcells. Surgical removal of this structure is a drasticway to force remission of myasthenia gravis. "Nude mice" come from strainswith mutations causing abnormalities in this structure, rendering them unable to reject graftfts. The process of positive selectionin the cortex of this organ determines whether some cells become the CD4+ or CD8+ strain. From puberty to old age,this organ can shrink to as much as one-sixth of its size. For 10 points, name this immune organ of T-cell maturation, which ispositioned in the chest in front of the heart.
This structure is absent in the "complete" DiGeorge's syndrome, though it is merely afflicted with aplasia in normal DiGeorge'ssyndrome.
thymus