Continuous Pax5 expression is required for their progenitors to develop from hematopoietic stem cells, due to the need for negative regulation.
Continuous Pax5 expression is required for their progenitors to develop from hematopoietic stem cells, due to the need for negative regulation. They undergo class switching, producing membrane-bound or secreted versions of proteins depending on the C-H coding sequences. Characterized by the presence of CD20 on their membranes, they undergo clonal selection, producing Ig-M early and Ig-D late in humoral immune response. Specializing into plasma and memory cells, FTP name this class of lymphocytes that are activated by helper T cells, and that are produced in the bone marrow.
Continuous Pax5 expression is required for their progenitors to develop from hematopoietic stem cells, due to the need for negative regulation.
{B} cells