A ribonucleoprotein, this reverse transcriptase is used to solve the end-replication problem in organisms with linear DNA.
Methods for detecting it include its namesake repeat amplification protocol and an assay using PharMingen. Containing a p123/Est2p polymerase domain, it is generally only found in cellular germplasm, unicellular eukaryotes, and some cancer cells. In 1998, a research group under Bodner transfected genes for it into human cells. In mammals, it provides an AAUCCC template to guide the insertion of TTAGGG. A ribonucleoprotein, this reverse transcriptase is used to solve the end-replication problem in organisms with linear DNA. For 10 points, name this enzyme that adds repeat sequences to the 3' ["three-prime"] end of DNA strands.
Methods for detecting it include its namesake repeat amplification protocol and an assay using PharMingen.
{telomerase}