The protein defective in this condition is generally anchored by a PDZ domain.
The protein defective in this condition is generally anchored by a PDZ domain. This condition is detected in a test that involves application of pilocarpine. Clubbed fingertips and toes are common in patients of this condition, and the protein defective in this condition functions as a thiocyanate (*) transported. This protein is most often caused by delta F-508 mutations, in which a phenylalanine residue is absent from a protein which transports sodium and chlorine across membranes. Patients of this disease have dangerously high lung mucus levels. For 10 points, name this disease whose patients have very high sweat chloride concentrations, which is abbreviated CF.
The protein defective in this condition is generally anchored by a PDZ domain.
cystic fibrosis [accept CF until mentioned]