The Bethesda system is used to score a test to detect its effects, and a preventative measure against it is the vaccine Gardasil.
Patients are predisposed to infection by this agent in the Lewandowsky-Lutz disorder. Tissue infected by this agent can be detected by immunostaining to detect co-expression of INK4a and Ki67. Two strains of this agent that infect the respiratory tract cause the disease RRP. An early gene in this agent significantly increases the degradation of Rb protein, which contributes to a process integral to Harald zur Hausen's hypothesis. This agent is known to undermine defense mechanisms by protecting host cells from TRAIL- induced apoptosis. Infection by a particularly virulent strain of this virus resulted in the HeLa cell line, and its 16 and 18 strains are examples of its "high-risk" strains. This virus causes intra-epithelial neoplasia in the region it targets. The Bethesda system is used to score a test to detect its effects, and a preventative measure against it is the vaccine Gardasil. For 10 points, name this virus that can cause genital warts and cervical cancer, infection with which can be diagnosed with a "smear."
Patients are predisposed to infection by this agent in the Lewandowsky-Lutz disorder.
HPV [or human papillomavirus; do not accept or prompt on "pap"]