The iron-sulfur protein aconitase catalyzes the isomerization of one molecule in this process to its iso- form.
Although it does not involve derivatives of malonic acid, the input to this pathway is formed by a complex containing many copies of the enzymes dihydrolipoyl transacetylase and E1, the latter of which requires the cofactor TPP. The iron-sulfur protein aconitase catalyzes the isomerization of one molecule in this process to its iso- form. An intermediate in this process inhibits phosphofructokinase, and calcium upregulates this process by activating alpha-ketoglutarate dehydrogenase. In one step of this process, succinate is oxidized to form fumarate. Acetyl-CoA reacts with oxaloacetate in the first step of this process, which occurs in the mitochondrial matrix and generates much of the NADH subsequently used for oxidative phosphorylation. For 10 points, name this process that succeeds glycolysis and is sometimes known as the tricarboxylic acid cycle.
Although it does not involve derivatives of malonic acid, the input to this pathway is formed by a complex containing many copies of the enzymes dihydrolipoyl transacetylase and E1, the latter of which requires the cofactor TPP.
Szent-Györgyi-Krebs cycle [or citric acid cycle; or tricarboxylic acid cycle or TCA cycle until it is read]