When found terminally on a carbon chain, they are very weakly acidic and form highly nucleophilic anions in the presence of sodium amide; these are often used to lengthen a carbon chain in a synthesis.
This functional group is often added to estradiol agonists to make orally active contraceptives. Hydroboration produces either an aldehyde or ketone via tautomerization from an enol intermediate, while an acidic potassium permanganate solution cleaves them and forms two carboxylic acids. When found terminally on a carbon chain, they are very weakly acidic and form highly nucleophilic anions in the presence of sodium amide; these are often used to lengthen a carbon chain in a synthesis. In a dissolving metal solution, they can be reduced to trans-alkenes, while hydrogenation in the presence of Lindlar's catalyst can reduce them to cis-alkenes. FTP, name this functional group composed of two carbons connected by a triple bond.
This functional group is often added to estradiol agonists to make orally active contraceptives.
{alkyne}s