These cells express ICOS, but not its ligand.
The creation of these cells is aided by the phosphorylation of LAT by ZAP-70, which is recruited by Lck. The TSLP protein assists in the creation of these cells. These cells express ICOS, but not its ligand. Secretory vesicles in these cells can contain the protein perforin, and they can also express the Fas ligand. Unlike some similar cells, these cells do not undergo somatic hypermutation, but they do undergo V(D)J recombination. MHC proteins present foreign peptides to these cells, which can contain the coreceptors CD4 and CD8. These cells are part of the cell-mediated immune response, distinguishing them from the antibody response. The two main classes of this cell are cytotoxic and helper. For 10 points, identify these lymphocytes that that mature in the thymus, unlike B cells.
The creation of these cells is aided by the phosphorylation of LAT by ZAP-70, which is recruited by Lck.
T cells [or T lymphocytes]