Formation of one kind sometimes requires treatment with a tosylate or mesylate in order to force formation via a SN2 mechanism and avoid rearrangement.
Because they possess pKa's ranging from 16-19, they can lose a hydrogen to form salts useful in ether synthesis. Formation of one kind sometimes requires treatment with a tosylate or mesylate in order to force formation via a SN2 mechanism and avoid rearrangement. Common laboratory methods for synthesizing these include the reaction of ketones with lithium aluminum hydride or the reaction of organolithium reagents with water. Mixing these with carboxylic acids will produce fruity smelling esters. For 10 points, name this class of organic compounds, with functional group OH, whose simplest example is methanol.
Because they possess pKa's ranging from 16-19, they can lose a hydrogen to form salts useful in ether synthesis.
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