In that reaction a transmetallation step is absent from the mechanism; after the universal oxidative addition step, the catalyst undergoes migratory insertion and beta-hydride elimination, followed by deprotonation.
While this chemist was employed at the Hercules Powder Company, he collaborated with his supervisor David Breslow to discover the general mechanism for hydroformylation. A better-known reaction named for this man has an intramolecular variant named for Mori and Ban, which can be used to synthesize indoles. This man's reaction originally involved the formation of trans-stilbene from the combination of styrene and iodobenzene. In that reaction a transmetallation step is absent from the mechanism; after the universal oxidative addition step, the catalyst undergoes migratory insertion and beta-hydride elimination, followed by deprotonation. That reaction creates carbon-carbon bonds by activating an alkene with a palladium catalyst, just like similar reactions named for Negishi and Suzuki, with whom this man shared the Nobel Prize in 2010. The namesake of a reaction also titled for Mizoroki, FTP, name this American chemist who pioneered transition metal catalysis with his cross-coupling reaction.
While this chemist was employed at the Hercules Powder Company, he collaborated with his supervisor David Breslow to discover the general mechanism for hydroformylation.
Richard Heck