For 10 points, name this degenerative neurological disorder, the most common cause of dementia in the elderly.
An allele of the apolipoprotein E gene on chromosome 19 increases the risk and lowers the age at onset of this disease. Microscopically it is characterized by Hirano bodies, and it results in changes in the nucleus basalis of Meynert. It is associated with "tangles," which show the MAP2 protein and abnormal forms of tau protein, as well as the presence of amyloid angiopathy and typical plaques, and symptoms include aphasia and progressive disorientation, indicating cortical dysfunction. Patients rarely become symptomatic before 50 years of age. but within the following 30 years up to 40% of the populace starts suffering from this disease. For 10 points, name this degenerative neurological disorder, the most common cause of dementia in the elderly.
An allele of the apolipoprotein E gene on chromosome 19 increases the risk and lowers the age at onset of this disease.
{Alzheimer}’s disease