This show's  pilot features the protagonist opening up his home to his divorced brother Alan and nephew Jake.  
In one episode of this TV series one protagonist accidentally burns down the house of his  girlfriend, Lyndsey MacElroy. One character in this series is married to pediatrician Herb  Melnick, who is portrayed by Ryan Stiles. The protagonist of this series is constantly stalked by  an ex-girlfriend named Rose and employs a wise-cracking housekeeper named Berta. This show's  pilot features the protagonist opening up his home to his divorced brother Alan and nephew Jake.  For 10 points, name this wildly popular CBS comedy that recently saw the addition of Ashton  Kutcher after the firing of Charlie Sheen.
In one episode of this TV series one protagonist accidentally burns down the house of his  girlfriend, Lyndsey MacElroy.
Two and a Half Men