FTP name this enzyme that catalyzes the reaction of carbon dioxide and water to form a proton and bicarbonate.
One inhibitor of this enzyme, acetazolamide, can be used to treat glaucoma and seizures, while another, topiramate, preferentially targets subtypes II and IV of the alpha class of this enzyme. Through convergent evolution, there are at least four classes of this enzyme, with the mammalian alpha group subdivided into cytosolic, mitochondrial, secreted, and membrane-associated versions. One of these using cadmium was found in a diatom, but the active site typically contains a zinc ion coordinated to three histidine residues and water, such that a polarized water molecule can attack the other reacting molecule it holds nearby. One of the fastest-acting biological enzymes, it is especially plentiful in red blood cells. FTP name this enzyme that catalyzes the reaction of carbon dioxide and water to form a proton and bicarbonate.
One inhibitor of this enzyme, acetazolamide, can be used to treat glaucoma and seizures, while another, topiramate, preferentially targets subtypes II and IV of the alpha class of this enzyme.
{carbonic anhydrase}