Their major disadvantage as compared to their counterpart is that they begin to denature after several weeks of storage, even at –80 degrees C.
Their major disadvantage as compared to their counterpart is that they begin to denature after several weeks of storage, even at –80 degrees C. To produce them, an animal is hyperimmunized, and then B cells are removed from the spleen. Polyethylene glycol is added to a culture containing both the B cells and myelomas, which then fuse to form immortal hybridoma cells. The hybridomas can then be screened and used to produce these identical immunoglobulins. FTP, name this type of antibody produced from a single B cell.
Their major disadvantage as compared to their counterpart is that they begin to denature after several weeks of storage, even at –80 degrees C.
{monoclonal} antibodies