For 10 points, identify this chromosome that contains the gene that codes for hexosaminidase A, which is mutated in Tay-Sachs disease.
A translocation between the RARA gene on chromosome 17 and the PML gene on this chromosome causes nearly all cases of acute promyelocytic leukemia. A pair of sister syndromes both due to a partial deletion on the q arm of this chromosome are classic cases of genomic imprinting and are Angelman and Prader-Willi syndrome. Mutations in the gene that codes for fibrillin-1, located on this chromosome, results in patients with elongated fingers that are at greater risk for aortic dissection in Marfan syndrome. Patients with an autorecessive disorder associated with this chromosome sport a cherry red macula and cannot break down GM2 gangliosides. For 10 points, identify this chromosome that contains the gene that codes for hexosaminidase A, which is mutated in Tay-Sachs disease.
A translocation between the RARA gene on chromosome 17 and the PML gene on this chromosome causes nearly all cases of acute promyelocytic leukemia.
chromosome 15