In pigs, this peptide's eighth amino acid residue is usually a lysine, but in humans, that residue is always arginine.
In pigs, this peptide's eighth amino acid residue is usually a lysine, but in humans, that residue is always arginine. Its receptors are blocked by tolvaptan, and it is sometimes inappropriately produced by small cell lung carcinomas. It is synthesized in the magnocellular neurons of the hypothalamus, and underproduction of or insensitivity to this hormone leads to diabetes insipidus. Its most important function sees it induce increased expression of aquaporin-2 in the collecting duct in the nephron, thus increasing blood volume. FTP, name this hormone produced by the posterior pituitary gland that causes water retention in the kidney and decreases the volume of the urine.
In pigs, this peptide's eighth amino acid residue is usually a lysine, but in humans, that residue is always arginine.
{A}nti-{D}iuretic {H}ormone or {vasopressin}