This molecule binds to and activates Protein Kinase A.
In Dictyostelium, RegA controls the concentration of this molecule, and oscillations in environmental concentrations of this molecule direct Dictyostelium aggregation. Forskolin triggers increased concentrations of this molecule. This molecule directly activates proteins called EPACs, which are guanine nucleotide exchange factors. Bordetella pertussis interferes with the immune system by causing the immune cells to increase production of this molecule. When glucose levels are low, it binds to the Catabolite Activator Protein in the lac operon, helping RNA polymerase bind to promoter sites during lac operon transcription. This molecule binds to and activates Protein Kinase A. It is cleaved by phosphodiesterase, and it is synthesized by adenylate cyclase. For 10 points, name this cyclic second messenger that is derived from ATP.
In Dictyostelium, RegA controls the concentration of this molecule, and oscillations in environmental concentrations of this molecule direct Dictyostelium aggregation.
cAMP [or cyclic AMP; or cyclic adenosine monophosphate]