Drugs that treat it, such as aliskiren and captopril (ah-LIS-kih-ren and CAP-to-pril), inhibit the proteases that cleave alpha-2-globulin into an 8-residue peptide and that degrade bradykinin ("brady"-KYE-nin).
A mutation in the amiloride-sensitive (ah-MIL-oh-"ride") protein ENaC causes a severe form of this condition called Liddle's syndrome. A drug that treats this condition was the ᥸rst designed rationally using QSAR and was based on a peptide extracted from a Brazilian viper. Drugs that treat it, such as aliskiren and captopril (ah-LIS-kih-ren and CAP-to-pril), inhibit the proteases that cleave alpha-2-globulin into an 8-residue peptide and that degrade bradykinin ("brady"-KYE-nin). Thiazides ("THIGH"-ah-zides) treat this condition, which was once the main target of the drug propranolol (pro-PRAN-uh-lahl) but today is treated using inhibitors of the reninÂ–angioÂ·tensinÂ–aldosterone system. Beta blockers are no longer recommended to treat this condition's primary form. This condition is diagnosed by a high result on a sphygmomanometer (s'fig-mom-ah-NOM-eh-ter) during both the systole and diastole. For 10 points, name this condition also called hypertension.
A mutation in the amiloride-sensitive (ah-MIL-oh-"ride") protein ENaC causes a severe form of this condition called Liddle's syndrome.
high blood pressure [accept hypertension before "hypertension"]