Prevacid (PREV-ah-sid) inhibits production of, for 10 points, what substance that causes esophageal re&amp;ux when it passes the pyloric sphincter and that gives a digestive organ a low pH?
Overproduction of this substance is caused by a tumor-secreted hormone in Zollinger-Ellison syndrome. Repeated exposure to this substance can turn stratified squamous epithelium into columnar epithelium. A protein named for this substance is synthesized in the antrum by G cells upon stimulation by bombesin (BOM-beh-sin). Antagonists of the H2 (h two) histamine receptor block production of this substance. Its production by cells with invaginations called canaliculi (can-ah-LICK-yoo-"lie") that express a hydrogen-potassium-ATPase can be inhibited by the PPI lansoprazole (lan-SOH-prah-zole). Parietal cells secrete both intrinsic factor and this substance, which cleaves pepsinogen into active pepsin. Prevacid (PREV-ah-sid) inhibits production of, for 10 points, what substance that causes esophageal re&amp;ux when it passes the pyloric sphincter and that gives a digestive organ a low pH?
Overproduction of this substance is caused by a tumor-secreted hormone in Zollinger-Ellison syndrome.
gastric acid [or stomach acid; accept hydrochloric acid or HCl; prompt on "acid"]