This virus attaches by binding to heparan sulfate proteoglycans with its glycoproteins B and C, after which its glycoproteins D, H, and L join together in a fusion complex.
This virus expresses ICP8, an unusually ATP- and magnesium-independent protein that anneals to single-stranded DNA. This virus disrupts host protein synthesis and degrades mRNAs with its virion host shutoff protein, which is encoded on its "long unique region" along with several of its capsid proteins. This virus attaches by binding to heparan sulfate proteoglycans with its glycoproteins B and C, after which its glycoproteins D, H, and L join together in a fusion complex. It causes "whitlow" lesions on fingers and thumbs. This virus maintains a reservoir by expressing latency associated transcript RNA while dormant in the sacral and trigeminal ganglia. This virus accounts for the 1 and 2 members of a large family that includes the Epstein–Barr and varicella zoster viruses. For 10 points, identify this "simplex" virus that causes both cold and genital sores.
This virus expresses ICP8, an unusually ATP- and magnesium-independent protein that anneals to single-stranded DNA.
herpes simplex virus [or HSV-1; or HSV-2; or HHV-1; or HHV-2; prompt on HHV] &lt;Biology&gt;