For 10 points, name this genus whose members cause Chagas disease and African sleeping sickness.
A hyper-modi ed nucleoÂ·base involved in RNA polymerase II termination, known as "base J," was  rst identi ed in a member of this genus. A disease caused by a member of this genus can be diagnosed from the presence of cardioÂ·megaly accompanied by apical atrophy. In a dramatic example of RNA editing, mitochondrial mRNAs in this organism are  rst synthesized entirely lacking uracils. DFMO, a suicide inhibitor of ornithine deÂ·carboxylÂ·ase, is an e fective treatment for a disease caused by members of this genus. These pathogens avoid the host immune system by periodically alternating their surface antigens with variant surface glycoÂ·proteins. A disease caused by a member of this genus begins with the appearance of swollen lymph nodes on the back of the neck, known as Winterbottom's sign. Members of this genus include species brucei ("bruce"-ee) and cruzi ("cruise"-ee). For 10 points, name this genus whose members cause Chagas disease and African sleeping sickness.
A hyper-modi ed nucleoÂ·base involved in RNA polymerase II termination, known as "base J," was  rst identi ed in a member of this genus.
Trypanosoma [or trypanosomes]