The core complex formed by these proteins consists of four alpha helices held together by the interaction of one glutamine with three arginines in a region known as the "zero ionic layer".
The core complex formed by these proteins consists of four alpha helices held together by the interaction of one glutamine with three arginines in a region known as the "zero ionic layer". One of these proteins lacks a transmembrane domain, so its function is dependent on palmÂ·itÂ·oylÂ·ation of cysteine residues in its DÂ·HÂ·HÂ·C domain. A protein responsible for dissociating these proteins from one another, named for its inactivation by N-ethylÂ·maÂ·leÂ·imÂ·ide, is the ATPase (a-t-p-"ace") NSF. For these proteins to act, complexin must 炤rst be displaced by the calcium sensor synaptotagmin. Members of the genus Clostridium cause botulism and tetanus by releasing toxins that lead to the cleavage of these proteins, which include syntaxin and synaptobrevin. For 10 points, name these proteins that mediate membrane fusion leading to vesicle exocytosis and neurotransmitter release.
The core complex formed by these proteins consists of four alpha helices held together by the interaction of one glutamine with three arginines in a region known as the "zero ionic layer".
SNAREs [or SNAP (Soluble NSF Attachment Protein) Receptor; accept syntaxin or synaptobrevin before each word is read]