The hormone that activates synthesis of this compound is part of the same polypeptide as melanocyte-stimulating hormone, which is why deficiencies in it often cause hyperpigmentation.
The hormone that activates synthesis of this compound is part of the same polypeptide as melanocyte-stimulating hormone, which is why deficiencies in it often cause hyperpigmentation. Dexamethasone agonizes this compound's receptors. It is made by adding three hydroxyl groups at carbons 11, 17, and 21 to progesterone in a pathway that diverges to make aldosterone. Poison ivy rashes are often treated by (*)  topical administration of this compound, which causes feedback inhibition of the hypothalamus-pituitary axis. This compound, which is overproduced in Cushing's syndrome, is made in a namesake part of the adrenal glands upon stimulation by ACTH. Like epinephrine, it raises blood sugar and pressure. For 10 points, name this steroid that regulates the body's "stress" response.
The hormone that activates synthesis of this compound is part of the same polypeptide as melanocyte-stimulating hormone, which is why deficiencies in it often cause hyperpigmentation.
cortisol  [or  hydrocortisone ; do not accept or prompt on "cortisone"] 