The enzymes tartrate-resistant phosphatase and cathepsin localize to this organelle in osteoclasts.
Senescent cells are detected in culture by the activity of a beta-galactosidase named for these cellular structures. Yoshinori Ohsumi  (OH-soo-mee)  discovered the APG hydrolases in these structures. The enzymes tartrate-resistant phosphatase and cathepsin localize to this organelle in osteoclasts. An enzyme found in these structures hydrolyzes GalNAc  (GALL-nack)  from the ganglioside GM2. MultiÂ·vesicular bodies ultimately (*)  fuse with these structures in receptor-mediated endocytosis. When it binds the autophagosome, this organelle initiates autophagy. Enzyme mutations lead to these organelles' "storage" disorders, like TayÂ–Sachs disease. Enzymes native to this organelle must be tolerant of very low pH. For 10 points, name these acidic vesicles that degrade proteins and are often called "suicide sacks".
Senescent cells are detected in culture by the activity of a beta-galactosidase named for these cellular structures.
 lysosome s [prompt on  endosome s; prompt on  vacuole s; prompt on  vesicles ]