Studies of related chloride peroxiÂ·dases have shown the catalytic cycle of these enzymes generally involves the formation of an iron-four oxo species, known as "Compound One.
A widely studied example of one of these enzymes in Pseudomonas putida allows the bacterium to use camphor as an energy source. A di ference spectrum assay can measure the amount of denaturation of these enzymes based on the shi t in their Soret peak. Studies of related chloride peroxiÂ·dases have shown the catalytic cycle of these enzymes generally involves the formation of an iron-four oxo species, known as "Compound One." BergaÂ·mottin is an inhibitor of these enzymes, which is why patients taking lipitor are advised not to drink grapefruit juice. Phenobarbital is used to increase expression of these enzymes in mice, and they can be isolated in EÂ·R microsomes. The conversion of testosterone to estraÂ·diol is accomplished by one of these enzymes called aromatase. These enzymes process xenobiotic (ZEE-nuh-bie-AH-tik) substrates in phase I of drug metabolism. For 10 points, identify this class of heme-dependent enzymes partially named for the maximum absorption wavelength that occurs when they are complexed with carbon monoxide.
A widely studied example of one of these enzymes in Pseudomonas putida allows the bacterium to use camphor as an energy source.
cytochrome p450 monoÂ·oxygenases [or p450s; or CYPs; prompt on cytochromes, heme(-dependent) monoÂ·oxygenases, heme(-containing) monoÂ·oxygenases, omega hydroxylÂ·ases; do not accept "cytochrome c"]