Another enzyme that hydrolyzes these molecules was first identified in a strain of K. pneumoniae ("k" new-MOHN-ee-ay) from New Delhi.
These compounds can be evaluated by measuring two parameters, h and c, named after Woodward and Cohen. The synthesis of one class of these molecules includes the cyclization of ACV by IPNS. Nitro·cefin can be used to test for the presence of enzymes that hydrolyze these molecules. pUC ("puck") plasmids encode an enzyme that hydrolyzes these molecules in their bla ("blah") gene. Another enzyme that hydrolyzes these molecules was first identified in a strain of K. pneumoniae ("k" new-MOHN-ee-ay) from New Delhi. The efficacy of these compounds can be increased by co-administration with cla·vu·lan·ic acid. A member of this class of molecules inhibits the enzyme DD-trans·pep·tid·ase, and they include carba·penems and cephalo·sporins. For 10 points, name this family of antibiotics distinguished by the presence of a four-member cyclic amide group, such as penicillin.
These compounds can be evaluated by measuring two parameters, h and c, named after Woodward and Cohen.
beta-lactams [or beta-lactam antibiotics; prompt on lactams]