Its transferases are fused as 220-residue tags for pull-downs in protein purification, during which this tripeptide is immobilized on beads.
Squid lens crystallins are homologous to a human enzyme with this compound as its substrate. Griffith devised an assay to detect this compound by reacting it with vinyl-pyridine; other classic methods either recycle this compound in a reaction with DTNB, forming a yellow acid, or just detect roGFP. This compound reacts with metallothionein to release zinc and form a four-member ring. Mercapturic acids are conjugates of this compound to toxic metabolites. Combined, it and ascorbate detoxify hydrogen peroxide. RNR's catalytic cycle uses either thioredoxin or a (*) redoxin named for this compound. This compound has a gamma-peptide bond where a glutamate side chain is linked to a free amino. Its transferases are fused as 220-residue tags for pull-downs in protein purification, during which this tripeptide is immobilized on beads. For 10 points, name this regulator of cellular redox state, symbolized GSH or GSSG.
Squid lens crystallins are homologous to a human enzyme with this compound as its substrate.
glutathione [or GSH or GSSG until they are read; or glutathione-S-transferase; or glutathione peroxidase]