This hormone was administered as part of the controversial Ashley Treatment to induce growth attenuation.
The G proteinÂ–coupled receptor GPR30 binds to this compound. T47D cells can lose receptors for this compound due to long-term deprivation in vitro. The indicator phenol red was shown to mimic this type of compound, and tamoxifen is an antagonist of its receptors. This hormone was administered as part of the controversial Ashley Treatment to induce growth attenuation. It is not progesterone, but it is produced in granulosa cells after they receive necessary precursors from thecal cells. Aromatase facilitates the conversion from androgens like testosterone to this hormone, which is why aromatase-inhibitors are sometimes an effective method for treating breast cancer. For 10 points, name this primary female sex hormone.
The G proteinÂ–coupled receptor GPR30 binds to this compound.
estrogens