They have been classified in 6 superfamilies, with those that do not form a ring structure in the first two superfamilies.
They have been classified in 6 superfamilies, with those that do not form a ring structure in the first two superfamilies. Cockayne syndrome results from errors in XPD, a domain with this type of activity, while mutations in RecQ family examples can cause Bloom syndrome or Werner syndrome. Proteins in the SWI and SNF families do not carry the namesake activity, although they have domains with this function. SV40 large tumor antigen was the first viral protein found to have this activity on DNA. Types of these that act on RNA include DEAD box proteins, while one of these that act on DNA in bacteria, DnaB, forms a hexamer that pushes open the replication fork. For 10 points, name these enzymes that unwind strands of nucleic acids.
They have been classified in 6 superfamilies, with those that do not form a ring structure in the first two superfamilies.
helicases