Both Gleevec, or Imanitib, and Genistein inhibit an enzyme ofthis amino acid, making them useful in the treatment of cancer, and those enzymes produce binding sitesfor proteins with an SH2 domain.
A breakdown product of this amino acid can lead to hypertensive crisis in people who takeMAOIs. Stanley Cohen discovered that the cell surface receptor that modifies this amino acid bindsto epidermal growth factor. The cell surface receptor that modifies this amino acid is bound byGRB2, which binds and activates Sos, which, in turn, activates Ras. DNA cleavage by alltopoisomerases is accompanied by the formation of a (*) phosphodiester bond between a residue of thisamino acid and an end of the broken strand. Both Gleevec, or Imanitib, and Genistein inhibit an enzyme ofthis amino acid, making them useful in the treatment of cancer, and those enzymes produce binding sitesfor proteins with an SH2 domain. This amino acid is the immediate precursor to melanin, and its namesakehydroxylase creates L-DOPA, the immediate precursor to dopamine. For 10 points, name this aromaticamino acid that is derived by hydroxylating phenylalanine, whose codons are UAC and UAU and which isabbreviated Y.
A breakdown product of this amino acid can lead to hypertensive crisis in people who takeMAOIs.
tyrosine [or 4-hydroxyphenylalanine; accept Y before it is read]