(*)
An alternative to SILAC called BONCAT uses substrates compatible with this reaction. THPTA stabilizes this reaction's catalyst, which is normally generated in situ by reduction with sodium ascorbate.  Highly strained eight-membered rings like OCT or BARAC are common substrates for this reaction. Carolyn Bertozzi developed non-canonical amino acids used in this reaction for labelling biomolecules. Its catalyst was discovered by Kolb 38 years after this reaction was named. MG Finn, Valery Fokin, and (*) Barry Sharpless will probably win a Nobel for this reaction, which is carried out at room temperature in water with a copper catalyst. Its product is a five-membered ring with three consecutive nitrogen atoms. For 10 points, name this 1,3-dipolar cycloaddition, a classic click reaction, in which a triazole is synthesized from an alkyne and an azide.
An alternative to SILAC called BONCAT uses substrates compatible with this reaction.
Huisgen cycloaddition [or alkyne-azide cycloaddition until "alkyne" is read; or CuAAC; or 1,3 dipolar cycloaddition until it is read; prompt on cycloaddition] 