Subtle signs of this illness in adults include anemia, and in this disease, tissue transglutaminase is attacked by antibodies, eliciting a B-cell response that increases production of IgA and IgG. That autoimmune response is caused by (*) prolamins, which, when presented to helper T-cells, generate the auto-antibodies.
The inhibition of the protein zonulin is a theorized treatment for Type I diabetes and this disease. It is associated with hyposplenism, and possession of the HLDA-DQ2 allele. The Marsh classification describes the pathogenesis of this disease, which involves the proliferation of intra-epithelial lymphocytes. Subtle signs of this illness in adults include anemia, and in this disease, tissue transglutaminase is attacked by antibodies, eliciting a B-cell response that increases production of IgA and IgG. That autoimmune response is caused by (*) prolamins, which, when presented to helper T-cells, generate the auto-antibodies. As with wheat allergy, the only definitive treatment is a lifelong gluten-free diet. For 10 points, name this autoimmune disease caused by Triticeae glutens which causes malnutrition and atrophy of the intestinal villi, named for the Greek word for "abdominal."
The inhibition of the protein zonulin is a theorized treatment for Type I diabetes and this disease.
Celiac disease