In 1956, the British Doctors' Study provided statistical proof linking this disease to its major risk factor.
The T790M mutation in EGFR is linked to this disease. Cells affected by one form of this disease contain an abnormal fusion between the EML4 and ALK genes. In 1956, the British Doctors' Study provided statistical proof linking this disease to its major risk factor. Horner's syndrome may be caused by infiltration into the sympathetic nervous system by Pancoast tumors in this disease. SIADH and Lambert-Eaton syndrome are common paraneoplastic consequences of this disease. This disease is broadly classified into (*) small-cell and non-small cell types, with roughly 40% of cases being adenocarcinomas. Radon gas exposure is a second major cause of this form of cancer. Worldwide, this disease is the cause of the most cancer-related deaths in both men and women. For 10 points, name this form of cancer observed in a high percentage of smokers. 
The T790M mutation in EGFR is linked to this disease. Cells affected by one form of this disease contain an abnormal fusion between the EML4 and ALK genes.
lung cancer [accept lung after "cancer" is read for the first time; accept the following before they are mentioned: small-cell cancer, non-small cell cancer; accept mesothelioma at all times; accept large-cell cancer before "small-cell" is read] 