Mutations in the SOD1 gene are found in some patients suffering from its familial variety which hurts their ability to attack free radicals, while the elevated presence of BMAA in the diet of the Chamorro people of Guam increases their risk of suffering from a complex of Parkinsonism and this disease.
Immunoblots of urea fractions from sufferers of it show that the misfolded TDP-43 protein is a major component of UBIs and similar pathological molecules are found in FTLD-U sufferers. Mutations in the SOD1 gene are found in some patients suffering from its familial variety which hurts their ability to attack free radicals, while the elevated presence of BMAA in the diet of the Chamorro people of Guam increases their risk of suffering from a complex of Parkinsonism and this disease. High levels of glutamate lead to widespread motor neuron degeneration, but patients retain their cognitive abilities. For 10 points, identify this disease, which Stephen Hawking suffers from and is also known as Lou Gehrig's disease.
Immunoblots of urea fractions from sufferers of it show that the misfolded TDP-43 protein is a major component of UBIs and similar pathological molecules are found in FTLD-U sufferers.
Amyotrophic Lateral Sclerosis or Lou Gehrig's Disease until mentioned