A deficiency of this molecule causes the degeneration of retinal neurons in a mitochondrially-inherited disease called Leber's Optic Neuropathy.
A deficiency of this molecule causes the degeneration of retinal neurons in a mitochondrially-inherited disease called Leber's Optic Neuropathy. The Schilling test is used to measure its uptake. It's not iron, but hypersegmented neutrophils are a finding of its deficiency. This molecule is the cofactor of the MTR protein, which synthesizes methionine from homocysteine. Myelin damage resulting from a deficiency of this molecule can be prevented if folic acid takes its place as the cofactor of methylmalonyl coenzyme A mutase in the production of succinyl coenzyme A. The inability of the parietal cells to produce intrinsic factor, which is necessary for this molecule's uptake, leads to a deficiency of this molecule in pernicious anemia. For 10 points, name this B vitamin with a central cobalt atom.
A deficiency of this molecule causes the degeneration of retinal neurons in a mitochondrially-inherited disease called Leber's Optic Neuropathy.
Vitamin B12 [accept specific vitamers such as cyanocobalamin or methylcobalamin or adenosylcobalamin]