Elevated dGTP levels are toxic to these cells, resulting in their depletion in PNP-deficiency.
Elevated dGTP levels are toxic to these cells, resulting in their depletion in PNP-deficiency. These cells mediate delayed-type hypersensitivity reactions, while a variety of them predominantly found in the submucosal lymphoid tissues is known as the "gamma-delta" type due to the composition of their namesake receptors. They're not NK cells, but the (*) CD8+ type of them secretes perforin to induce cytolysis. Autoreactive ones are eliminated in a process called negative selection, and Interleukin-2 is released when antigens associated to Class I MHC molecules bind to their namesake receptors. HIV infects the CD4+ variety of these cells, which are a subset of the "helper" variety.. Responsible for cell-mediated immunity, for 10 points, name these white blood cells which mature in and are named for the thymus.
Elevated dGTP levels are toxic to these cells, resulting in their depletion in PNP-deficiency.
T cells [or T lymphocytes; or thymocytes before "thymus" is read]