For 10 points, name this mid-Atlantic railroad that spanned from a port city to a Midwestern state.
The Jones-Imboden raid and the McNeill raid both aimed at disrupting this company, which was led by Daniel Willard during the early decades of the 20th century. This company exclusively used the Bollman Truss, which was designed by one of its engineers. Its president John W. Garrett alerted Lew Wallace about Confederate activity before the Battle of Monocacy, which was fought to protect its local junction. Peter Cooper designed the Tom Thumb to convince the owners of this railroad to use (*) steam power. The Great Railroad Strike of 1877 began in response to this railroad cutting wages three times in one year. After John Brown's raid seized one of its trains, this railroad transported government soldiers to Harper's Ferry. Stonewall Jackson conducted a campaign to sabotage this railroad in 1861 because it was the only railroad into Washington D.C. After being incorporated in 1827, it was the first American railroad to offer regular passenger and freight service. For 10 points, name this mid-Atlantic railroad that spanned from a port city to a Midwestern state. 
The Jones-Imboden raid and the McNeill raid both aimed at disrupting this company, which was led by Daniel Willard during the early decades of the 20th century.
Baltimore and Ohio railroad [or the B and O railroad]