Its not dihydroxylation, but a mixture of sodium periodate and osmium tetroxide will perform a transformation identical to this reaction, called the Lemieux-Johnson Oxidation.
Its not dihydroxylation, but a mixture of sodium periodate and osmium tetroxide will perform a transformation identical to this reaction, called the Lemieux-Johnson Oxidation. This reaction is used to produce azelaic acid from oleic acid on a large scale, and this reaction generates atheronals from LDL-cholesterol in atherosclerotic plaques. This reaction is often carried out in methanol at -78 degrees Celsius until the solution turns blue, which indicates consumption of the reactant. Its mechanism contains a retro-1,3-dipolar cycloaddition flanked by two forward dipolar cycloadditions, and sees the formation of a (*) trioxalane after a carbonyl and carbonyl oxide attack each other; that step is the Crigee intermediate. Oxidative workup of this process sees the formation of two carboxylic acids, though most of the time reductive workup is used to generate two carbonyls. For 10 points, name this reaction which uses a namesake triatomic gas to split a double bond.
Its not dihydroxylation, but a mixture of sodium periodate and osmium tetroxide will perform a transformation identical to this reaction, called the Lemieux-Johnson Oxidation.
Ozonolysis