Colostrum is particularly rich in this protein, which is responsible for the passive immunity transmitted to infants through milk.
It has nothing to do with "red man syndrome", but an unusual side effect of vancomycin is a linear bullous dermatosis caused by this protein. People with a selective deficiency of this protein can undergo anaphylactic shock if transfused with whole blood. This protein can be selectively purified using Peptide M and SSL7, and it binds to CD89 on effector cells. This protein and complement factor 3 form complexes in blood vessel walls in Henoch-Schonlein purpura. This protein contains an unusual glycosylated proline-rich hinge region. M cells in the intestinal wall allow this protein and its binding partners to transcytose into (*) Peyer's patches. One section of this protein is encoded by the alpha-1 and alpha-2 regions of a particular locus, which are switched to using TGF-beta signaling. This protein polymerizes through the action of its J-chain. Colostrum is particularly rich in this protein, which is responsible for the passive immunity transmitted to infants through milk. For 10 points, name this antibody isotype that exists as a dimer, and is heavily present on mucosal surfaces and secretions.
It has nothing to do with "red man syndrome", but an unusual side effect of vancomycin is a linear bullous dermatosis caused by this protein.
IgA [or immunoglobulin A; prompt on immunoglobulin or antibody]