Caused by a bacterium in the mycobacterium genus and screened for using a skin test, for 10 points, name this lung disease that kills a lot of people in the third world, drug users, and inmates.
The causative agent of this disease has an H37Rv strain genome sequenced. One drug used to treat this disease inhibits arabinosyl transferase. Another drug used to treat it inhibits the product of the pncA gene. In addition to ethambutol and pyrazinimide, another drug used to treat it is activated by KatG and inhibits the synthesis of mycolic acid. The milliary form of it occurs in immunocompromised patients, and infected tissues commonly have caseating granulomas and Langhans Giant Cells. The causative agent of this disease inhibits the maturation and acidification of phagosomes after being devoured by macrophages, and that agent is an acid-fast bacillus that is detected using a Ziehl-Nielsen stain. This disease is treated using Rifampicin and Isoniazid. Besides night sweats, fatigue, and weight loss, this disease makes patients cough up blood. Caused by a bacterium in the mycobacterium genus and screened for using a skin test, for 10 points, name this lung disease that kills a lot of people in the third world, drug users, and inmates.
The causative agent of this disease has an H37Rv strain genome sequenced.
Tuberculosis