Like Wiskott-Aldrich syndrome protein, physical interaction with this protein inhibits Src kinase, an effect that can be relieved by g-strophanthin and other inotropic agents.
FXYD proteins serve as tissue-specific modulators of this protein. Like Wiskott-Aldrich syndrome protein, physical interaction with this protein inhibits Src kinase, an effect that can be relieved by g-strophanthin and other inotropic agents. Isoforms of this protein that have alpha 1 and 2 units have increased affinity for one of their substrates when acted on by insulin. The cytoplasmic face of this protein is phosphorylated in the second step of its mechanism, which causes an inversion of its conformation. The transport of glucose through GLUT2 from intestinal epithelial cells into the bloodstream is facilitated by the gradient created by this protein, which is potently inhibited by ouabain and digoxin. For 10 points, name this integral membrane protein that transports two cations of one element into a cell for every three cations of another element it transports out.
FXYD proteins serve as tissue-specific modulators of this protein.
sodium potassium ATPase [accept "pump" in place of "ATPase"; accept Na+ K+ pump] 