By inspecting the x-axis of a Lineweaver-Burke plot, one can differentiate between the oft-confused uncompetitive and non-competitive forms of this process.
At low concentrations, the Cheng-Prusoff equation provides a biased estimate of this process's equilibrium constant. The selectivity of this process can be probed against hundreds of targets at once in ABPP-MudPIT analysis. Different mechanisms for this process can be modeled by setting the parameter alpha to almost zero, exactly one, or to a very large value. Irreversible complexes consisting of covalently-bonded analogues participate in the (*) "suicide" form of this process. The IC50 measure indicates the concentration at which this process is at half of its maximal effectiveness. By inspecting the x-axis of a Lineweaver-Burke plot, one can differentiate between the oft-confused uncompetitive and non-competitive forms of this process. For 10 points, name this process in which molecules bind to enzymes, decreasing their activity.
At low concentrations, the Cheng-Prusoff equation provides a biased estimate of this process's equilibrium constant.
enzyme inhibition [prompt on enzyme modulation; prompt on answers along the lines of changing the activity of an enzyme] 