Deregulated activity of one protein in this enzyme family can be triggered by a "chimeric" Bcr protein, and deregulation of that one of these enzymes named for Abelson is a key sign of chronic myeloÂ·genous leukemia.
Deregulated activity of one protein in this enzyme family can be triggered by a "chimeric" Bcr protein, and deregulation of that one of these enzymes named for Abelson is a key sign of chronic myeloÂ·genous leukemia. Another member of this family of enzymes becomes constitutively active in its viral form due to the loss of its C-terminal residues, and the non-viral form of that enzyme from this family is encoded for by the (*) SRC gene. A different one of these enzymes ultimately catalyzes the downstream dimerization of STAT transcription factors and is named for its nearly-identical transfer domains.  In a classic feedback loop, the serine-threoÂ·nine residues on one variety of these enzymes is phosphorylated by their MAP3 variety. For 10 points, name these enzymes that function in the transfer of phosphate groups.
Deregulated activity of one protein in this enzyme family can be triggered by a "chimeric" Bcr protein, and deregulation of that one of these enzymes named for Abelson is a key sign of chronic myeloÂ·genous leukemia.
kinases [accept Abl kinases, Src kinases, any form of MAP kinase, (receptor/non-receptor)-tyrosine kinases, or serine-threonine kinases] 