For 10 points, name this enzyme that catalyzes the first step in the pentose phosphate pathway by removing a hydrogen from a certain phosphorylated sugar.
The Cosenza variant of this protein has around 10% the activity of its normal form, and other variants of it include ones named for Orissa and the Mediterranean. Analyzing uterine tissue from heterozygous women with A and B variants of this protein led Linder, Gartler, and Townsend et al. to show that fibroids originate from single myometrial cells. Patients with low levels of this enzyme sometimes show "bite cells" on pathology and should avoid dapsone and primaquine. This enzyme catalyzes a reaction that produces a lactone, and is the first in a pathway whose final products are NADPH and (*) ribose 5-phosphate. It is the namesake of the most common hereditary enzyme disorder, which can be triggered by oxidative stresses like eating fava beans. For 10 points, name this enzyme that catalyzes the first step in the pentose phosphate pathway by removing a hydrogen from a certain phosphorylated sugar.
The Cosenza variant of this protein has around 10% the activity of its normal form, and other variants of it
glucose-6-phosphate dehydrogenase [or G6PD; or G6PDH]