For 10 points, name this process catalyzed by DNApolymerase before the start of mitosis, the copying of the genome.
One protein involved in this process is helped by sliding clamps, and several proteins involved inthis process are transcribed in response to E2F activation. It is initiated by cdc6 binding to the ORCcomplex. The formation of secondary structures during this procedure is prevented by SSBs. Anexperiment to characterize this process used a cesium chloride gradient to centrifuge E. coli that hadbeen grown in a nitrogen-15 medium. (*) Okazaki fragments are used to cover the lagging strand in thisprocedure, which is initiated by helicase prying the strands apart to create a fork. Meselson and Stahlshowed that this process is semiconservative. For 10 points, name this process catalyzed by DNApolymerase before the start of mitosis, the copying of the genome.
One protein involved in this process is helped by sliding clamps, and several proteins involved inthis process are transcribed in response to E2F activation.
DNA replication [or S phase]