For 10 points, name this disease that is caused by insulin resistance, and is often split into Type 1 and Type 2.
The gene PGC-1 Alpha has been found to instruct humans with this condition to produce less effective mitochondria when methylated by cytokines (**). Another study shows that in men, having low testosterone makes one more susceptible (*) to this disease because it signals that the endocrine system is not functioning well. Acanthosis nigricans, a harmless skin darkening, can occur in those that have this disease. In patients that are of average weight, sulfonylureas may be prescribed to treat the disease, while in overweight patients, metformin has been found to be more effective in inhibiting gluconeogenesis. For 10 points, name this disease that is caused by insulin resistance, and is often split into Type 1 and Type 2.
The gene PGC-1 Alpha has been found to instruct humans with this condition to produce less effective mitochondria when methylated by cytokines (**).
diabetes mellitus (accept Type 1 or Type 2 diabetes)