They secrete cathepsin K and tartrate-resistant acid phosphatases through their ruffled borders.
An enzyme native to these cells contains an iron (II)-iron (III) cluster, is bright pink in solution, and is labelled 5b because it produces an unusual fifth band in SDS-PAGE. The gray-lethal mutation in mice causes overproduction of these cells. The ClC-7 chloride channel is coupled to a V-type ATPase in these cells' membranes. Helper T-cells that make interleukin-17 are named for their resemblance to these cells, which, like T cells, have transcription globally regulated by NFAT-c1. DC-STAMP fuses these cells' precursors to form their active (*) multinucleated counterparts. OPG, a decoy for the RANK ligand, inhibits production of these cells, which also requires co-stimulation by MCSF-1. Bisphosphonates activate apoptosis of these cells. They secrete cathepsin K and tartrate-resistant acid phosphatases through their ruffled borders. For 10 points, name these cells found in crevasses called Howship's lacunae, which increase blood calcium levels by breaking down bone.
An enzyme native to these cells contains an iron (II)-iron (III) cluster, is bright pink in solution, and is labelled 5b because it produces an unusual fifth band in SDS-PAGE.
osteoclasts [do NOT accept or prompt on "osteoblasts"]