For this reaction, a chair transition state is assumed by the Zimmerman-Traxler model, which predicts that anti products arise from E enolates.
A directed version of this reaction can be performed using an imine and lithium diisopropylamide, and an asymmetric version of this reaction is catalyzed by proline and is named for Parrish and Hajos. Enantioselectivity in this reaction can be achieved using an acyl oxazolidinone chiral auxiliary in a method developed by David Evans. For this reaction, a chair transition state is assumed by the Zimmerman-Traxler model, which predicts that anti products arise from E enolates. This reaction follows a (*) Michael addition in the Robinson annulation reaction. For 10 points, name this reaction in which two carbonyl-containing compounds react to form the namesake compound containing a carbonyl group and an alcohol.
A directed version of this reaction can be performed using an imine and lithium diisopropylamide, and an asymmetric version of this reaction is catalyzed by proline and is named for Parrish and Hajos.
aldol addition or reaction or condensation