Several of them bind to the 30S ribosomal subunits to prevent translation, although the 50S subunit is bound to by the aminoglycoside variety and peptidoglycan synthesis is inhibited by the beta-lactam kind.
One class of these substances possesses an amide functionality connected to the last of four six-membered rings. A specific compound of this type prevents the synthesis of tetrahydrofolic acid. The effectiveness of these substances can be enhanced by drugs that block Pol II, Pol IV, and Pol V, thus limiting the SOS response that is triggered when these substances cause DNA damage. Several of them bind to the 30S ribosomal subunits to prevent translation, although the 50S subunit is bound to by the aminoglycoside variety and peptidoglycan synthesis is inhibited by the beta-lactam kind. MRSA has developed resistance to many of these substances. For 10 points, penicillin was the first effective kind of what agents used to treat bacterial infections?
One class of these substances possesses an amide functionality connected to the last of four six-membered rings.
antibiotics [accept tetracyclines in the first sentence; accept antibacterials prior to mention of "bacteria"]