Support for this idea is given by Michael Yarus' Direct-templating model, and as a test of this hypothesis was the creation of the 218-unit long Spiegelmann's monster and other autocatalytic sets.
Support for this idea is given by Michael Yarus' Direct-templating model, and as a test of this hypothesis was the creation of the 218-unit long Spiegelmann's monster and other autocatalytic sets. Hollinger's creation of the R18 molecule lends more credence to this hypothesis, which some attempt to use to explain homochirality by positing a selective non-enzymatic aminoacylation step. Alternatives to this theory include the iron-sulfur or metabolism first models and panspermia. This idea was posited in a paper by Walter Gilbert and supported by Crick and Orgel, and is supported by the existence of self-catalyzing introns and other ribozymes. For 10 points, name this hypothesis which posits that life began based on self-replicating molecules of a particular type of nucleic acid that is not DNA.
Support for this idea is given by Michael Yarus' Direct-templating model, and as a test of this hypothesis was the creation of the 218-unit long Spiegelmann's monster and other autocatalytic sets.
RNA World Hypothesis