One form of this disease includes higher levels of 14-3-3 proteins, high levels of PrPSc, and an MRI giving a (*) pulvinar sign" are associated with this disease's "variant" form.
A tossup on this disease in ACF Nationals 2006 noted that it was diagnosed by searching the EEG for triphasic spikes. The inherited form of this disease is caused by mutations on the PRNP gene, and cases of this disease from transplanted corneas and improperly sterilized electrodes in the brain are called (+)  "iatrogenic" cases, which contrasts with the "sporadic" cases. One form of this disease includes higher levels of 14-3-3 proteins, high levels of PrPSc, and an MRI giving a (*) pulvinar sign" are associated with this disease's "variant" form. This incurable disease leads to ataxia, dementia, and death within one year, as a result of cavities forming in the brain. For 10 points, identify this disorder, a spongiform encephalopathy in humans which is caused by prions and is often associated with mad cow disease, named for two German scientists.
A tossup on this disease in ACF Nationals 2006 noted that it was diagnosed by searching the EEG for triphasic spikes.
Creutzfeldt-Jakob Disease