The monomers of these molecules contain two heavy and two light chains connected by a disulfide bond.
The Bence-Jones protein is a derivative of these proteins that is hypersecreted in multiple myeloma patients. IP assays use these molecules to pull targets out of solution by taking advantage of their binding to protein A and protein G. Fab fragments are generated when Papain cleaves these molecules at their hinge region, and one subtype of them contains a J chain connecting two elements of a dimer. One of these is applied to a PVDF membranes with proteins affixed to it in a Western blot. The monomers of these molecules contain two heavy and two light chains connected by a disulfide bond. For 10 points, identify these Y-shaped proteins secreted by the immune system to target pathogens.
The Bence-Jones protein is a derivative of these proteins that is hypersecreted in multiple myeloma patients.
Antibodies or immunoglobulins