One uprising against this man was led by Spitamenes.
This man was raised by a woman named Lanike [lah-NEE-kay], who was the sister of a future general of this man named Cleitus [KLI-tus] the Black. One uprising against this man was led by Spitamenes. An army led by this man and his father defeated a coalition army of many of the Greek city-states at the battle of Chaeronea [ker-uh-NEE-uh]. This man's father, Phillip II, allegedly stated," My boy, you must find a kingdom big enough for your ambitions" after this man tamed the horse Bucephalus. For 10 points, name this king of Macedon who won the 333 BC Battle of Issus and also named multiple cities after himself, including the Egyptian seaport of Alexandria. 
This man was raised by a woman named Lanike [lah-NEE-kay], who was the sister of a future general of this man named Cleitus [KLI-tus] the Black.
Alexander the Great [accept Alexander III of Macedon]  