Kawada and Cohen used a combination of an HDAC6 inhibitor and a protease inhibitor to selectively kill cells infected with this virus, and cells infected with it show upregulated fgr tyrosine kinase.
Kawada and Cohen used a combination of an HDAC6 inhibitor and a protease inhibitor to selectively kill cells infected with this virus, and cells infected with it show upregulated fgr tyrosine kinase. Expression of its nuclear antigens are controlled epigenetically through the Wp, Cp, and Qp promoters, and also encodes for a series of miRNAs near its BART and BHRF1 genes, the latter of which is a Bcl2 homologue. Its latent cycle is promoted by the transmembrane proteins LMP-1 and 2, and causes hairy leukoplakia in AIDS patients. Also responsible for post-transplant lymphoproliferation, this virus is associated with a disease that sees a translocation of c-myc and a starry sky appearance under an H&E stain, called Burkitt's lymphoma. For 10 points, name this herpesvirus that infects B-cells and commonly causes mononucleosis.
Kawada and Cohen used a combination of an HDAC6 inhibitor and a protease inhibitor to selectively kill cells infected with this virus, and cells infected with it show upregulated fgr tyrosine kinase.
{Epstein-Barr} virus