This disease is diagnosed using the El Escorial criteria. Its familial variety is most commonly associated with a defect in the superoxide dismutase gene and has been found in only 149 patients, with an endemic focus in Guam.
This disease is diagnosed using the El Escorial criteria. Its familial variety is most commonly associated with a defect in the superoxide dismutase gene and has been found in only 149 patients, with an endemic focus in Guam. The drug Riluzole has been shown to delay its progression by inhibiting glutamate excitoxicity, but most patients will require a tracheotomy within two to four years as widespread motor and respiratory dysfunction progresses. 15% of sufferers will experience dementia, but cognition is often preserved intact, as in the case of a well-known Lucasian chair. FTP, name this disease, notable victims of which include Stephen Hawking and Lou Gehrig.
This disease is diagnosed using the El Escorial criteria. Its familial variety is most commonly associated with a defect in the superoxide dismutase gene and has been found in only 149 patients, with an endemic focus in Guam.
{A}myotrophic {L}ateral {S}clerosis (Prompt on buzz of “Lou Gehrig’s disease”)