This chemist claimed that his most exciting achievement was his total synthesis of the eight L-hexoses with Masamune.
This chemist claimed that his most exciting achievement was his total synthesis of the eight L-hexoses with Masamune. A reaction named for him and Katsuki uses t-butyl-peroxide and titanium tetra-iso-propylate. His namesake ligands are di-hydro-quinidine derivatives used in another namesake reaction, which has an alkene treated with osmium tetroxide in a method similar to Upjohn dihydroxylation. His lab pioneered a method he calls "click chemistry," featuring assembly of compounds from small blocks of readily available materials. The above reactions are his production of vicinal diols from alkenes, and his Nobel-winning production of asymmetric epoxides from allylic alcohols. FTP, name this chemist ►hailed by Eric Mukherjee and hated by Selene Koo.
This chemist claimed that his most exciting achievement was his total synthesis of the eight L-hexoses with Masamune.
K(arl) Barry {Sharpless}