Patients with this disease often have chronic Burkholderia cepacia infections.
Patients with this disease often have chronic Burkholderia cepacia infections. The protein central to this disease contains an ATP-binding cassette motif and a PDZ domain. Its earliest symptom is neonatal intestinal blockage. It is associated with male infertility due to agenesis of the vas deferens. Sufferers are unable to secrete pancreatic enzymes, leading to those enzymes damaging the pancreas itself. The sweat test was used to diagnose this condition before (*) genetic testing, and it results in the inability to pass chloride ions through cell membranes. Percussive vests are a common treatment, and it is the most common autosomal recessive disease among Europeans. For 10 points, name this genetic disease in which mucus builds up in the lungs.
Patients with this disease often have chronic Burkholderia cepacia infections.
cystic fibrosis [or CF]