This class of proteins is carboxymethylated and stored in Mallory bodies in hepatocytes.
This class of proteins is carboxymethylated and stored in Mallory bodies in hepatocytes. Filaggrin binds to members of this protein family. These proteins are split into two homology classes: acidic and basic. Epidermolysis bullosa simplex is caused by a defect in one of these proteins. The alpha class of them forms a coiled coil. Cells named for these proteins differentiate in a process called (*) cornification, and are shed through desquamation. These proteins are easily oxidized because of their high concentration of sulfur. They make up a major class of intermediate filaments. 95% of the epidermis consists of cells that make these proteins. For 10 points, name this class of strong proteins found in human hair and fingernails.
This class of proteins is carboxymethylated and stored in Mallory bodies in hepatocytes.
keratins [or cytokeratins]