Some methods for performing this task use quality trimming to improve accuracy.
Some methods for performing this task use quality trimming to improve accuracy. One method for accomplishing this task is based on the detection of pyrophosphate release.  There are several methods for performing this task in parallel, which are known as "next-generation" methods and which include the "ion semiconductor" method and the "Polony" method. One method for accomplishing this uses molecules which lack a (*) 3'-hydroxyl group, preventing the formation of phosphodiester bonds; that method, the chain-termination method, replaced the Maxam-Gilbert method and was developed by Sanger. Since the Sanger method can only be used for short molecules, the "shotgun" method for this task is used with long molecules. For 10 points, name this task which involves determining the order of nucleotides in a certain molecule.
Some methods for performing this task use quality trimming to improve accuracy.
DNA sequencing [prompt on partial answers]