This cell type's namesake activating factor is targeted by the monoclonal antibody Benlysta.
This cell type's namesake activating factor is targeted by the monoclonal antibody Benlysta. These cells express both CD19 and CD20 on their surfaces, and immortalized ones are fused with normal ones to form hybridomas. They proliferate in response to IL-4 and IL-5, and these cells get their names from the unique organ in which they mature in birds. One protein expressed by them is encoded for by genes that undergo somatic hypermutation. Those genes undergo the (*) VDJ recombination to create diversity. They can be divided into memory and plasma types, the latter of which secrete large amounts of antibodies in response to an infection. For 10 points, name this type of immune cell, which, unlike T-cells, mature in the bone marrow.
This cell type's namesake activating factor is targeted by the monoclonal antibody Benlysta.
B cell