This virus's ZEBRA protein acts as an energy-independent cell-penetration peptide.
This virus's ZEBRA protein acts as an energy-independent cell-penetration peptide. Its LMP2A protein allows it to take control of a host cell's Src tyrosine kinases through immunoreceptor tyrosine activation based motifs. This virus infects epithelial cells lacking the CD21 receptor, but during its lysogenic stage it stays hidden in B cells. This virus is a co-carcinogen with nitrosamines, with which it plays a role in nasopharyngeal carcinoma in East Asian populations, and it also acts as a carcinogen in sub-Saharan African populations to cause Burkitt's lymphoma. It is spread through saliva, and the disease with which it is most commonly associated causes severe fatigue and can lead to rupture of the spleen. For 10 points, name this herpesvirus, which causes infectious mononucleosis.`
This virus's ZEBRA protein acts as an energy-independent cell-penetration peptide.
Epstein-Barr virus [or human herpesvirus 4; or HHV4]