One assumption made in deriving it is that as long as the initial velocity is considered, the concentration of the product can be neglected.
One assumption made in deriving it is that as long as the initial velocity is considered, the concentration of the product can be neglected. A physically meaningful limit of this equation is that of small initial velocities, in which case the velocity displays first-order kinetics, since it becomes proportional to the substrate concentration. In its full form, a plot of the velocity against the substrate concentration yields a rectangular hyperbola, whose horizontal asymptote represents saturation. Demonstrating that the substrate concentration that produces half the maximum reaction rate is equal to half its namesake constant, FTP, identify this equation which relates the reaction rates of reactions catalyzed by enzymes to the initial concentration as a function of the substrate concentration.  1
One assumption made in deriving it is that as long as the initial velocity is considered, the concentration of the product can be neglected.
Michaelis-Menten equation