This substance is the major toxin involved in scombroid poisoning.
This substance is the major toxin involved in scombroid poisoning. Tritoqualine is an atypical antagonist of this compound that targets the enzyme involved in its formation. Four G-protein coupled receptors are known for it in humans. Its degradation primarily proceeds through either amine oxidase or its namesake N-methyltransferase. Other alkaloids can displace it in its granules, causing its release. Excreted by enterochromaffin-like cells and by mast cells, it is produced by the decarboxylation of an amino acid with an imidazole side chain. For 10 points, what is this substance inhibited by ranitidine and diphenhydramine that provokes an inflammatory response?
This substance is the major toxin involved in scombroid poisoning.
histamine