In the Van den Burgh reaction, a water-soluble form of this is reacted with diazotized sulfanilic acid to form a purple substance.
In the Van den Burgh reaction, a water-soluble form of this is reacted with diazotized sulfanilic acid to form a purple substance. Very high levels of this can be caused by the Crigler-Najjar syndrome and the Dubin-Johnson syndrome. In mammals, this substance is present essentially as a glucuronide conjugate. Its structure is an open chain tetrapyrole and the conjugation is catalyzed by the liver microsomal enzyme uridyl diphosphoglucuronyltransferase. The decomposed product of the normal catabolization of heme, for 10 points, name this substance responsible for the discoloration in those afflicted with jaundice found in the gallbladder and the predominant orangish-yellow pigmentary component of bile.
In the Van den Burgh reaction, a water-soluble form of this is reacted with diazotized sulfanilic acid to form a purple substance.
Bilirubin