Its most common variant causes a progressive deterioration of mental and physical abilities that commence around six months of age and usually ends in death by age four.
Its most common variant causes a progressive deterioration of mental and physical abilities that commence around six months of age and usually ends in death by age four. Long associated with Ashkenazi Jews, it also disproportionately affects Irish, French Canadians, and Cajun populations. Occurring when harmful quantities of cell membrane components known as gangliosides accumulate in the brain's nerve cells, eventually leading into the cells premature death. For ten points, name this autosomal recessive genetic disorder.
Its most common variant causes a progressive deterioration of mental and physical abilities that commence around six months of age and usually ends in death by age four.
{Tay-Sachs} disease or {GM2} gangliosidosis or {hexosaminidase A deficiency}