Degenerative fibrosis of its tissue is one of the major causes of Sick Sinus Syndrome.
Degenerative fibrosis of its tissue is one of the major causes of Sick Sinus Syndrome. Phenylalkylamines and benzothiazepines negate the abilities of its Cav3 channels, (*) which are expressed at high density in this area to allow for a massive flux of calcium ions. Adrenaline causes it to act with more automaticity, making its resting potential even more unsteady and causing increased heart rate. Lying at the top of the right atrium where it is met by the superior vena cava, FTP, name this bundle of Purkinje fibers which sends an electrical signal causing the heart to pump blood, and is thus a natural pacemaker.
Degenerative fibrosis of its tissue is one of the major causes of Sick Sinus Syndrome.
{sinoatrial} node (or {SA} node or {sinoauricular} node)