One type of cell found in this organ possess Birbeck's granules, and overproliferate in the disease
One type of cell found in this organ possess Birbeck's granules, and overproliferate in the disease Histiocytosis X. Another type of cell found in this organ may be derived from the neural crest and are characterized by the use of tyrosinase in their central function. Cell-cell junctions within this organ are compromised in diseases like pemphigus foliaceous and pemphigus vulgaris, which disrupt (*) desmosomal proteins. It houses eccrine and apocrine glands, as well as arrector pili bundles. This organ has four main layers:  The spinous layer, home to Langerhans cells; the thin granular layer; the basal layer, which houses melanocytes; and the thick stratum corneum, which contains anucleate keratin plates that are eventually shed. It is formed primarily of stratified squamous epithelium, and lies immediately above the basement membrane zone. For 10 points, identify this organ, whose outermost layer is known as the epidermis.
One type of cell found in this organ possess Birbeck's granules, and overproliferate in the disease
the skin [accept epidermis before mentioned; prompt on "integumentary system]