The HyperMu system uses these to sequence cDNA libraries, and the Sleeping Beauty system is a potential therapeutic application of them.
The HyperMu system uses these to sequence cDNA libraries, and the Sleeping Beauty system is a potential therapeutic application of them. Michael Simmons discovered a type of them in D. Melanogaster called P elements, which are commonly used in mutagenesis studies, and they're believed to be evolutionarily related to the VDJ system in immunoglobulin expression. The first to be discovered were the Ac and Ds elements, and the most common in humans is the Alu repeat. They are classified into either Class I or II, depending on whether they use reverse transcription or a cut-and-paste mechanism to achieve their most noteworthy function. FTP, name these genetic elements first discovered in Zea Mays by Barbara McClintock, colloquially referred to as "jumping genes"?
The HyperMu system uses these to sequence cDNA libraries, and the Sleeping Beauty system is a potential therapeutic application of them.
{Transposons} or {Transposable elements} (prompt on “jumping genes” before mention)