Peng and Song reported a variant of this reaction which uses simultaneous ultrasound and microwave irradiation, which does not require the use of phase-transfer catalysts like tetra-n-butylammonium bromide.
Peng and Song reported a variant of this reaction which uses simultaneous ultrasound and microwave irradiation, which does not require the use of phase-transfer catalysts like tetra-n-butylammonium bromide. Sodium hydride or carbonate bases are used to deprotonate one reactant in this reaction, and an intermolecular version of this reaction can be performed on halohydrins. An iodide salt can be used to speed up this reaction via halide exchange. A sterically hindered reactant can lead to (*) alkene formation in this reaction, because this reaction proceeds via an alkoxide attacking an alkyl halide in an SN2 reaction. For 10 points, name this reaction which is used to form compounds containing oxygen single bonded to two carbons.
Peng and Song reported a variant of this reaction which uses simultaneous ultrasound and microwave irradiation, which does not require the use of phase-transfer catalysts like tetra-n-butylammonium bromide.
Williamson ether synthesis