This substance is notably unable to treat a disease caused by the mutation of the PHEX protein, and this substance's receptor can also be activated by lithocholic acid.
This substance is notably unable to treat a disease caused by the mutation of the PHEX protein, and this substance's receptor can also be activated by lithocholic acid. This substance causes the upregulation of TRPV6 in intestinal cells by binding to a nuclear receptor. Harrison's groove, rachitic rosary, and the valgus deformity are symptoms of deficiency in this substance. Its synthesis starts from 7-dehydroholesterol, followed by hydroxylation in the 25-position in the liver and in the 1-position in the kidney. The activation of this substance is reliant on parathyroid hormone, this substance results in the increased uptake of calcium in the kidneys and intestines. For 10 points, name this vitamin deficient in rickets, which is synthesized in the skin from UV light and found in milk.
This substance is notably unable to treat a disease caused by the mutation of the PHEX protein, and this substance's receptor can also be activated by lithocholic acid.
Vitamin D