An enzyme that catalyzes the formation of this compound has erythrocyte, liver, and muscle isoforms, and is deficient in a condition that creates "burr cells." An oxidized lipoate species with a "swinging arm" is attacked by an anionic carbon in a TPP cofactor in the three-enzyme complex that dehydrogenates this compound. This compound's carboxylase catalyzes the formation of oxaloacetate in the first step of (*) gluconeogenesis. In anaerobic conditions, NAD+ can be regenerated by converting this compound to lactate. In respiration, this compound is made into acetyl-CoA, which then enters the citric acid cycle. For 10 points, name this three-carbon compound that is the end-product of glycolysis.
An enzyme that catalyzes the formation of this compound has erythrocyte, liver, and muscle isoforms, and is deficient in a condition that creates "burr cells." An oxidized lipoate species with a "swinging arm" is attacked by an anionic carbon in a TPP cofactor in the three-enzyme complex that dehydrogenates this compound. This compound's carboxylase catalyzes the formation of oxaloacetate in the first step of (*) gluconeogenesis. In anaerobic conditions, NAD+ can be regenerated by converting this compound to lactate. In respiration, this compound is made into acetyl-CoA, which then enters the citric acid cycle. For 10 points, name this three-carbon compound that is the end-product of glycolysis.
An enzyme that catalyzes the formation of this compound has erythrocyte, liver, and muscle isoforms, and is deficient in a condition that creates "burr cells.
pyruvate [or pyruvic acid] 