For 10 points, name this disorder in which one becomes dependent on the active drug found in tobacco.
The six-item Fagerstrom Test assesses the severity of this disorder. The second most common use of the antidepressant bupropion is treatment of this disorder. The drugs cytisine and varenicline treat this disorder by being partially agonistic to a type of receptor that appears on both sides of the neuromuscular junction. The non-alpha 7 types of that receptor contribute to this disease by directly exciting dopaminergic and GABAergic neurons. The compound most directly responsible for this condition mimics the action of acetylcholine in namesake acetylcholine receptors. The most common way to treat this disorder is through replacement therapy in the form of gum or patches. For 10 points, name this disorder in which one becomes dependent on the active drug found in tobacco.
The six-item Fagerstrom Test assesses the severity of this disorder.
nicotine addiction [or nicotine dependence; prompt on "smoking" or any other answer indicating tobacco ingestion]