Substituted derivatives of these compounds are first reacted with phosphorus oxychloride and then with an electron-rich arene to form iminium ions in the Vilsmeier-Haack reaction.
In the three-component Biginelli reaction, ethyl acetoacetate reacts with aryl aldehydes and urea to form compounds of pharmaceutical interest containing two of this functional group. In another reaction, primary examples of these compounds are reacted with bromine and then with base to form isocyanates. Substituted derivatives of these compounds are first reacted with phosphorus oxychloride and then with an electron-rich arene to form iminium ions in the Vilsmeier-Haack reaction. DMF is an example of one of these compounds. They can also be formed by the hydrolysis of nitriles, although they are more commonly formed by the reaction of amines with acyl chlorides. For 10 points, name these compounds which consist of a carbonyl group bonded to a nitrogen.
In the three-component Biginelli reaction, ethyl acetoacetate reacts with aryl aldehydes and urea to form compounds of pharmaceutical interest containing two of this functional group.
amides [do not accept or prompt on "amines"]