Basal linear andbasal laminar deposits appear in this disease between the RPE and Bruch's membrane, which may bedisrupted with neovascularization.
A strong predictor of this disease is the Arg-80-Gly variant of the complement C3 gene. Basal linear andbasal laminar deposits appear in this disease between the RPE and Bruch's membrane, which may bedisrupted with neovascularization. People with this disease perceive wavy lines on an Amsler grid. It mayadvance to central geographic atrophy in a type characterized by buildup of drusen. The abnormalangiogenesis in the "wet" form of this disease can be inhibited by injecting drugs directly into the vitreoushumor. The namesake affected structure in this disorder is a yellow spot in the center of the retina, soperipheral vision is usually retained. For 10 points, name this age-related disease that manifests as progressivecentral vision loss. 
A strong predictor of this disease is the Arg-80-Gly variant of the complement C3 gene.
age-related macular degeneration