These enzymes act on the same substrate as catalase, and catalyze the production of two alcohols by breaking an oxygen-oxygen single bond.
Antibodies to an enzyme in this family produce the P-ANCA staining pattern around the nucleus in rapidly progressive glomerulonephritis. That enzyme in this family is responsible for the green color of green sputum. One family of these enzymes is characterized by a catalytic triad of glutamine, tryptophan, and selenocysteine. Along with lysozyme and lactoferrin, an enzyme in this family kills bacteria in saliva and milk. One enzyme in this family is targeted by antibodies in Hashimoto's disease and "organifies" iodine in the thyroid. One of these enzymes produces hypochlorous acid during the respiratory burst of neutrophils. They're not phosphatases, but an enzyme in this class is a commonly-used reporter enzyme in ELISA and Western blots, and was isolated from the roots of horseradish. These enzymes act on the same substrate as catalase, and catalyze the production of two alcohols by breaking an oxygen-oxygen single bond. For 10 points, name these enzymes that facilitate the breakdown of H2O2.
Antibodies to an enzyme in this family produce the P-ANCA staining pattern around the nucleus in rapidly progressive glomerulonephritis.
peroxidase [or haloperoxidase; or lactoperoxidase; or myeloperoxidase; or glutathione peroxidase; or horseradish peroxidase]