This process is often described using an energy (*) funnel.
This process is coupled with binding and recognition in the fly-casting mechanism. Drummond and Wilke proposed that failures in this process create a universal anti-correlation dN/dS and expression. This process is often described using an energy (*) funnel. Levinthal's paradox says that if this occurred via totally random changes in state, it would take more time than the age of the universe, which argues against Anfinsen's dogma that this process is determined only by the original structure. This process involves the formation of structures like the DNA clamp, the TIM barrel, and disulfide bonds. It is often mediated by chaperone proteins and it is stabilized by interactions between amino acids. For 10 points, name this process where polypeptides gain tertiary structure and become functional.
This process is coupled with binding and recognition in the fly-casting mechanism.
protein folding [accept anything involving getting tertiary or quaternary structure for proteins; prompt on partial answers]