In humans, it is synthesized through the action of serine hydroxymethyltransferase with the help of a folate cofactor, and it is combined with succinyl-CoA in the formation of delta-ALA in the first step of (*) porphyrin synthesis.
It's not Tris, but during immunoprecipitation, a solution of this nucleophile is used to quench the crosslinking reaction. A pH 2.5 solution of this substance can be used to strip western blots. In humans, it is synthesized through the action of serine hydroxymethyltransferase with the help of a folate cofactor, and it is combined with succinyl-CoA in the formation of delta-ALA in the first step of (*) porphyrin synthesis. Strychnine is an antagonist of this molecule's receptor, which is responsible for triggering inhibitory potentials in the spinal cord. This molecule's presence can disrupt the formation of an alpha helix due to its high entropy cost, though with proline it is present very frequently in collagen helices due to its high flexibility. For 10 points, name this only achiral amino acid, the simplest one with a side chain containing only a hydrogen atom.
It's not Tris, but during immunoprecipitation, a solution of this nucleophile is used to quench the crosslinking reaction.
glycine [or gly or G]