For 10 points, identify these organelles that are important in the autolysis of cells.
Along with microtubules, these entities are recruited to facilitate the invasion of the host cell by the parasite T. Cruzi, and the protein hVam6p is responsible for the clustering of these entities in humans.  Glycogen buildup in these entities in muscle cells results in Pompe's disease, and the lack of fat-metabolizing enzymes in it is the cause of Tay-Sachs disease. Mannose-6-phospate is tagged to proteins bound for this organelle, which pumps protons into itself for maintaining an acidic environment.  For 10 points, identify these organelles that are important in the autolysis of cells.
Along with microtubules, these entities are recruited to facilitate the invasion of the host cell by the parasite T. Cruzi, and the protein hVam6p is responsible for the clustering of these entities in humans.  
{lysosome}s