The Hajos-Parrish reaction extends its utility by allowing for enantioselective products from this reaction, particularly the Wieland- Miescher ketone.
The Hajos-Parrish reaction extends its utility by allowing for enantioselective products from this reaction, particularly the Wieland- Miescher ketone. The Wichterle reaction uses a dichlorobutene derivative to perform alkylation rather than (*) methyl vinyl ketone, while the closely related Hauser reaction employs a Dieckman condensation and elimination in the second step to produce naphtalene derivatives, in place of this reaction's usual intramolecular condensation.  Through its formation of an alpha, beta- unsaturated cyclic ketone product, it is a key reaction for the production of complex cyclic molecules.   For 10 points, this is what reaction that combines the Michael addition with an aldol condensation?
The Hajos-Parrish reaction extends its utility by allowing for enantioselective products from this reaction, particularly the Wieland- Miescher ketone.
{Robinson} annulation (4) [AU]