It can occur via the intrinsic pathway, the extrinsic pathway, and the kallikrien pathway, and it results in the cleavage of fibrinogen of fibrin.
Several proteins in this pathway contain Kringle domains. Patients with antiphospholipid antibody syndrome produce a factor that hyperactivates this process, which can be detected using the Russell Viper Venom Test. Congenital defects in this process include a particular G-20210-A mutation and TTP. One assay used to test for defects in this process is reported in terms of an international normalized ratio, and Lovenox is used to inhibit it. The PT and aPTT test are used to find defects in this process, which is inhibited by (*) heparin. It can occur via the intrinsic pathway, the extrinsic pathway, and the kallikrien pathway, and it results in the cleavage of fibrinogen of fibrin. Christmas disease and von Willebrand disease results from defects in this pathway, which contains proteins C, K, and Z as well as factors one through twelve. Factor 8 in this pathway is mutated in hemophilia. For 10 points, name this process that ensures that one doesn't bleed to death.
Several proteins in this pathway contain Kringle domains. Patients with antiphospholipid antibody syndrome produce a factor that hyperactivates this process, which can be detected using the Russell Viper Venom Test.
Blood Clotting or Coagulation