These structures contain cytochrome c, which is released from this organelle's inner membrane as part of apoptosis; that inner membrane has folds in it called cristae.
One mutation affecting these organelles can cause a disorder characterized by loss of motor control and lactic acidosis, Leigh's disease, and salt and pepper retina pigmentation is a characteristic of another disease related to malfunction of these organelles. Impermeability of part of this structure to NADH leads to the use of the (*) malate-aspartate shuttle to translocate electrons in these organelles, and translocation of proteins into them is mediated by the TIM/TOM complex. They are the site of a process that sees the irreversible dehydrogenation of alpha-ketoglutarate into succinyl-coA. These structures contain cytochrome c, which is released from this organelle's inner membrane as part of apoptosis; that inner membrane has folds in it called cristae. For 10 points, name this organelle that has its own matrilineal DNA and is the site of most of the production of ATP in a cell.
One mutation affecting these organelles can cause a disorder characterized by loss of motor control and lactic acidosis, Leigh's disease, and salt and pepper retina pigmentation is a characteristic of another disease related to malfunction of these organelles.
{mitochondria}