An overdose of one type of these drugs is treated using protamine sulfate.
One side effect of one of these drugs is diagnosed using the 4T scale and is caused by antibodies to PF4. Another side effect of one of these drugs is a horrific eschar-forming skin necrosis. One class of drugs of this type consists of synthetic pentasaccharides like fondaparinux, while argatroban is the prototype of another class. An overdose of one type of these drugs is treated using protamine sulfate. Several drugs of this type work by forming a ternary complex with AT-III. One drug of this type has several low-molecular weight varieties that are easier to manage, while the effects of another one are monitored using the (*) international normalized ratio. One drug of this type inhibits an epoxide reductase which transforms vitamin K to its active form and was originally used as a rat poison. For 10 points, name these drugs that include Coumadin and Heparin, which stop hemostasis.
One side effect of one of these drugs is diagnosed using the 4T scale and is caused by antibodies to PF4.
anticoagulants [or blood thinners; accept any answer involving stopping blood clotting, but do NOT accept “anti-platelet” meds or equivalents or “clot-busting” or “thrombolytic” drugs or equivalents, accept more specific answers like: factor ten-A inhibitors, direct thrombin inhibitors, coumarins, Coumadin, warfarin, heparins, etc]