One attempt to create a vaccine for this disease using a 42-amino acid-long peptide was halted in 2002 when it resulted in encephalitis in 6% of the trial patients.
One attempt to create a vaccine for this disease using a 42-amino acid-long peptide was halted in 2002 when it resulted in encephalitis in 6% of the trial patients. Later stages of this disease involve massive nitric oxide release from cells following activation of calcium-sensing receptor. NMDA receptor antagonists such as memantine are used to treat the late-stage symptoms of this disease. Down syndrome patients can exhibit (*) early-onset of this disease due to the overexpression of APP. Arginine-112 and arginine-158 mutations in apolipoprotein E are closely linked to this disease. Tau tangles and beta-amyloid plaques are hallmarks of this disease. For 10 points, name this most common neurodegenerative disease that results in dementia.
One attempt to create a vaccine for this disease using a 42-amino acid-long peptide was halted in 2002 when it resulted in encephalitis in 6% of the trial patients.
Alzheimer’s disease