A gating theory of this was given by Melzack and Wall, who implicate the dorsolateral tract of Lissauer between spinal segments of Rexed lamina V.  It is lost in Brown-Sequard syndrome, and potentiated by the action of bradykinin on TRP channels.   
A gating theory of this was given by Melzack and Wall, who implicate the dorsolateral tract of Lissauer between spinal segments of Rexed lamina V.  It is lost in Brown-Sequard syndrome, and potentiated by the action of bradykinin on TRP channels.   The perception of it is inhibited by the action of periaqueductal gray, and a study by Liem et. al. claims that redheads are more susceptible to the thermal type.  The fast acute type travels via A-delta fibers toward the dorsal horn, while the dull slow type travels via C fibers. Divided into cutaneous, visceral, somatic, or neuropathic forms, it results from stimulation of nociceptors.  This is, FTP what sensation defined as an unpleasant sensory and emotional experience associated with tissue damage or injury?
A gating theory of this was given by Melzack and Wall, who implicate the dorsolateral tract of Lissauer between spinal segments of Rexed lamina V.  It is lost in Brown-Sequard syndrome, and potentiated by the action of bradykinin on TRP channels.   
{pain}  