This process occurred spontaneously after removal of urea from ribonuclease A in an experiment named for Anfinsen.
Kuhlman et al. designed Top7 to undergo this process in a way not found in nature. One protein that assists this process has seven subunits in its cis and trans phases and has a very hydrophobic equatorial domain; that protein, GroEl, forms a complex with GroEs and ATP. Hydrophobic interactions are the major driving force of this process and it involves the formation of an intermediate called a (*) molten globule. This process occurred spontaneously after removal of urea from ribonuclease A in an experiment named for Anfinsen. In eukaryotes, Hsp60, Hsp70, and other chaperones assist this process that causes the formation of structures like beta barrels and and alpha helices. For 10 points, name this process which certain macromolecules get their three-dimensional structure.
Kuhlman et al. designed Top7 to undergo this process in a way not found in nature.
protein folding [prompt on answers involving the formation of secondary or tertiary structure]