TAPs ["T-A-P"s] bring peptides to the ER, where they bind with these molecules.
Altman et al. used tetramers of these molecules with fluorophore-labeled streptavidin in diagnostics. TAPs ["T-A-P"s] bring peptides to the ER, where they bind with these molecules. Because of their beta-2 microglobulin subunit, one class of them can only (*) present epitopes to cells with CD8 co-receptors. APCs like dendritic cells express class II of these molecules. They must be matched between host and donor in organ transplants. For 10 points, name these cell surface molecules that display antigens for recognition by T cells, used to distinguish self from non-self.
Altman et al. used tetramers of these molecules with fluorophore-labeled streptavidin in diagnostics.
major histocompatibility complex [or MHC; accept MHC class I, MHC class II, or MHC class III; prompt on "Human Leukocyte Antigen," "HLA," or "H-2"]