A mode of transport for excess acetyl coA to prevent slowing of the Krebs cycle and speeding of gluconeogenesis during starvation and diabetes, they allow beta oxidation to proceed and accumulate in blood in acidosis.
They are produced by cleaving the beta-hydroxy-beta-methylglutaryl coA intermediate using a lyase in mitochondrial matrix, after thiolase joins 2 acetyl coAs and HMG coA synthase adds in a third along with water. Produced when insulin is deficient, other members of the family come from reduction and decarboxylation of acetoacetate to D-beta-hydroxybutyrate and odorous acetone. A mode of transport for excess acetyl coA to prevent slowing of the Krebs cycle and speeding of gluconeogenesis during starvation and diabetes, they allow beta oxidation to proceed and accumulate in blood in acidosis. For ten points, name these alternative fuels containing a functional group found on acetone.
They are produced by cleaving the beta-hydroxy-beta-methylglutaryl coA intermediate using a lyase in mitochondrial matrix, after thiolase joins 2 acetyl coAs and HMG coA synthase adds in a third along with water.
{ketone bodies} (prompt on “ketones”)