It's not RNA, but an enzyme whose substrate is this molecule contains a C-terminal "flap domain" which covers the active site after substrate binding, which occurs at a connection between that enzyme's L and S domains referred to as the "cis loop.
It's not RNA, but an enzyme whose substrate is this molecule contains a C-terminal "flap domain" which covers the active site after substrate binding, which occurs at a connection between that enzyme's L and S domains referred to as the "cis loop." The Arg-590 residue of that enzyme whose substrate is this molecule interacts with the fluorophenyl group of that enzyme's type 2 inhibitors. This molecule is formed, then subsequently cleaved, in the beginning of a pathway regulated by the transcription factor SREBP-2. This molecule is cleaved by its namesake lyase to form acetoacetic acid during the formation of ketone bodies. This molecule's thioester group is reduced to an alcohol to form mevalonate, which is phosphorylated and decarboxylated to form the precursors to isoprenoids and various steroids. For 10 points, name this compound whose namesake reductase is inhibited by statins.
It's not RNA, but an enzyme whose substrate is this molecule contains a C-terminal "flap domain" which covers the active site after substrate binding, which occurs at a connection between that enzyme's L and S domains referred to as the "cis loop.
HMG-CoA [or, god forbid, 3-hydroxy-3-methylglutaryl-coenzyme A]