For 10 points, identify this autosomal recessive disorder especially prevalent among Caucasian populations, characterized by an accumulation of thick, viscous mucus in the lungs.
A classic symptom of this disease is salty-tasting skin, and congenital bilateral absence of the vas deferens is a common finding in affected males. Â One major function of the protein implicated in this disease is secretion of bicarbonate from pancreatic duct cells, leading to pancreatic insufficiency and failure to thrive. Â Management for this disease may include (*) chest percussion, which helps decrease the risk of opportunistic infection by microbes like Pseudomonas aeruginosa. Â Such microbes take advantage of decreased mucociliary function to colonize the lungs. Â The most common mutation causing this illness is deltaF508, which deletes a single phenylalanine from the epithelial chloride channel CFTR. Â For 10 points, identify this autosomal recessive disorder especially prevalent among Caucasian populations, characterized by an accumulation of thick, viscous mucus in the lungs.
A classic symptom of this disease is salty-tasting skin, and congenital bilateral absence of the vas deferens is a common finding in affected males.
cystic fibrosis [prompt on CF]