This reaction is highly stereoselective and when used to form bicyclic compounds, the endo-cycloadduct is generally found in large excess over the exo product.
This reaction is highly stereoselective and when used to form bicyclic compounds, the endo-cycloadduct is generally found in large excess over the exo product. The rate and yield of this reaction can be increased by the presence of electron-withdrawing groups such as nitrile or carbonyl on the dienophile [di-EEN-oh-phile]. The simplest form of this reaction occurs between ethylene and 1,3-butadiene, and produces cyclohexene. FTP, name this reaction which won the 1950 Chemistry Nobel for its German discoverers.
This reaction is highly stereoselective and when used to form bicyclic compounds, the endo-cycloadduct is generally found in large excess over the exo product.
{Diels-Alder} reaction