A ternary complex consisting of eIF4G
In 2010, the FDA briefly suspended one of the two vaccines for this virus because porcine circovirus was detected in it. A ternary complex consisting of eIF4G I, RoXaN, and NSP3 can be detected in cells infected this virus; during translation, the latter protein binds to an mRNA that is unusually capped, but not polyadenylated. After a calcium gradient in the endosome causes the trimers of this virus's VP7 protein to break down, its VP2 and VP6 proteins form a double-(*) layered particle around the double stranded RNA. The three-layered icosahedral capsid of this member of family Reoviridae enables it to survive the low pH of the stomach. By the age of five, nearly every child on the planet will have been infected with this virus at least once. For 10 points, identify this most common viral cause of diarrhea in young children, named for its wheel-like shape.
In 2010, the FDA briefly suspended one of the two vaccines for this virus because porcine circovirus was detected in it.
rotavirus