This reaction proceeds via a chair-shaped transition state according to the (*) ZimmermanÂ–Traxler model.
Either the Claisen reaction or this reaction is used to form the initial ring in a polyketide compound. A common introductory organic chemistry lab experiment involves using this reaction to synthesize chalcones. An enzyme named for this reaction converts fructose 1,6-diphosphate to DHAP and G3P during glycolysis. This reaction proceeds via a chair-shaped transition state according to the (*) ZimmermanÂ–Traxler model. This reaction forms the ring in the Robinson annulation. Under base catalysis, this reaction contains an addition step where an enolate attacks a carbonyl, followed by an elimination step where water is removed to form an alpha-beta unsaturated ketone. For 10 points, name this condensation reaction named for the two functional groups present in its intermediate.
Either the Claisen reaction or this reaction is used to form the initial ring in a polyketide compound.
aldol reaction [accept aldol condensation or aldol addition; accept aldolase]