For ten points, identify this chronic autoimmune disease.
Patients with this disease often exhibit elevation of proinflammatory cytokines and TH-2 cytokines concentrations. Severe cases of this have been successfully treated with autologous bone marrow stem cell transplants, and the activation of type-I interferon systems has been shown to correlate with the presence and activity of this disease. Genes thought to be important to this disease are located on chromosome 6, and people with this disease always have a RUNX-1 binding site. A temporary drug-induced version of this disease can be brought about via quinidine and Phenytoin .This disease often results in irregular apoptotis, and the name is thought to be derived from the malar rash, which purportedly resembles the pattern on the face of a wolf. For ten points, identify this chronic autoimmune disease.
Patients with this disease often exhibit elevation of proinflammatory cytokines and TH-2 cytokines concentrations.
systemic {Lupus} erythematosis