These cells uniquely express VE-cadherin and CD141 on their surface.
Antibodies to these cells are found in Susac's syndrome. Precursors to these cells are marked by the ID1 gene. A signalling peptide named for these cells has receptors inhibited by Bosentan and Ambrisentan, which are used to treat pulmonary hypertension. These cells uniquely express VE-cadherin and CD141 on their surface. They contain storage granules called Weibel-Palade bodies, which contain P-selectin and von Willebrand factor. Those found in the (*) liver sinusoids are separated by fenestrae. These cells help comprise the tunica intima, and Furchgott originally discovered nitric oxide as a "relaxing factor" derived from them. The space underneath these cells is filled with lipids in atherosclerosis. For 10 points, name these cells which regulate vascular tone and are found on the inner surface of blood vessels.
Antibodies to these cells are found in Susac's syndrome. Precursors to these cells are marked by the ID1 gene.
endothelial cells