The activation of the adaptor protein Apaf-1 can initiate this  pathway because it can activate caspases.
Hemopoetic cells undergo this process in the absence of colony- stimulating factors. One technique used to study cells  performing this process involves using a terminal deoxynucleotidyl transferase. The Annexin V ("5") assay detects the  occurrence of this process, which is inhibited during late stages of herpes simplex virus infections. This process can begin  with the binding of (*) Fas ligands released by certain T cells to target Fas receptors. Proteins that mediate this process are  themselves regulated by the Bcl2 class of proteins. A class of proteins that mediates this process has a cysteine residue at their  active site and cleave their substrates after aspartic acid residues. The activation of the adaptor protein Apaf-1 can initiate this  pathway because it can activate caspases. For 10 points, the mitochondrial release of cytochrome c can trigger what process of  programmed cell death?
Hemopoetic cells undergo this process in the absence of colony- stimulating factors.
apoptosis [accept programmed cell death until mentioned]  4