This disease, splenomegaly, and neutropenia make up Felty's triad.
Expansions of the gut bacterium Prevotella copri are associated with the worsening of this disease. Disease activity in this condition is measured by the DAS28 score. Susceptibility to this disease is conferred by the HLA-DRB1 shared epitope motif. This disease, splenomegaly, and neutropenia make up Felty's triad. A combination of this disease and coal exposure can cause lung nodules, a condition called Caplan's syndrome. This disease is treated using DMARDs, some of which, like adalimumab and (*) infliximab, inhibit TNF-alpha. This disease, whose symptoms include Z-deformities, swan-neck deformities and morning stiffness, has a namesake "factor", which is an IgM antibody that targets the IgG constant region. For 10 points, name this autoimmune disease that causes pain and inflammation in small joints.
Expansions of the gut bacterium Prevotella copri are associated with the worsening of this disease.
rheumatoid arthritis [or RA]