This pathway occurs in the cytosol, and its first step involves the creation of glucose-6-phosphate by hexokinase.
A catalytically perfect enzyme in this pathway interconverts DHAP with GADP. A key regulator of this process is allosterically inhibited by a high ratio of ATP to AMP; that enzyme irreversibly converts fructose-6-phosphate to fructose-1,6-bisphosphate and is called PFK-1. The Warburg effect refers to the fact that cancer cells tend to have elevated rates of this process, followed by (*) lactic acid fermentation. This pathway occurs in the cytosol, and its first step involves the creation of glucose-6-phosphate by hexokinase. Because it uses two ATP and yields four, this pathway has a net gain of two ATP. During aerobic respiration, this pathway precedes the Krebs cycle. For 10 points, name this metabolic pathway in which glucose is turned into two pyruvate molecules.
A catalytically perfect enzyme in this pathway interconverts DHAP with GADP.
glycolysis