These cells both constitutively express class II MHC molecules and, without requiring activation, have costimulatory activity, differentiating them from other APCs.
The Flt3/Flk2 kinase is an "excellent marker" for differentiating these cells from macrophages. A type of these cells found in the epidermis is characterized by the presence of racket-shaped structures containing CD207, called Birbeck granules. CD103+/CD11b− and CD11b+ are the major subtypes of their "classical" type. These cells both constitutively express class II MHC molecules and, without requiring activation, have costimulatory activity, differentiating them from other APCs. They include (*) Langerhans cells, and their follicular type is involved in maintaining B cell memory. They process and present antigens to activate T cells, forming the backbone of the adaptive immune response. For 10 points, name these cells of the immune system that resemble the branched projections of neurons
The Flt3/Flk2 kinase is an "excellent marker" for differentiating these cells from macrophages.
dendritic cells [or: DCs; prompt on: "Langerhans cells"]