Before ester hydrolysis, this reaction is the mechanism by which atracurium breaks down in the bloodstream.
The alkaloid petaline degrades to leonticine rapidly via this reaction. Before ester hydrolysis, this reaction is the mechanism by which atracurium breaks down in the bloodstream. The Wittig modification of this reaction uses strong bases to force it into an E1 mechanism. This reaction is central to the Herzig-Meyer determination test, and in cyclic systems this reaction's product is dependent on the availability of beta-hydrogens. For straight-chain compounds, this reaction tends to form the less-substituted product in opposition to Zaitsev's rule. The first step of this reaction is involves adding excess methyl iodide, followed by treatment with silver oxide and water to form an alkene via an E2 mechanism. For 10 points, name this elimination reaction in which an amine is removed.
The alkaloid petaline degrades to leonticine rapidly via this reaction.
Hofmann Elimination