The primary reagent in it is sold commercially as a complex with THF or diethyl ether because its raw form is such a strong Lewis acid.
Rhodium is often used to generate catalytic asymmetric varieties of this reaction. The primary reagent in it is sold commercially as a complex with THF or diethyl ether because its raw form is such a strong Lewis acid. This reaction is commonly performed in laboratories preceding an oxidation using a peroxide, but the hydroxyl group added may be replaced with an amine or a halogen. This reaction is a syn-addition, and may also be used to make ketones and aldehydes from alkynes, considering the enol-carbonyl tautomerism. The first part of this reaction is concerted, with the reagent adding across the alkene to form a square transition state. For ten points, identify this key reaction, the anti-Markovnikov addition of water across a double bond using a certain group three element.
Rhodium is often used to generate catalytic asymmetric varieties of this reaction.
{hydroboration}-oxidation