When undergoing this reaction, triphenylphosphines tend to give the cis- isomer while trialkylphosphines will yield the trans- isomer.
When undergoing this reaction, triphenylphosphines tend to give the cis- isomer while trialkylphosphines will yield the trans- isomer. A strong base such as sodium hydride or sodamide is used to make one of the reactants, and the stable compound phosphine oxide is the by-product. A four-member ring intermediate is formed, and the reaction moves quickly due to the strength of the phosphorus-oxygen bond. FTP identify this versatile reaction, which uses a phosphorane or ylide to convert an aldehyde or a ketone into an alkene.
When undergoing this reaction, triphenylphosphines tend to give the cis- isomer while trialkylphosphines will yield the trans- isomer.
Wittig reaction