They release a substance that is broken  down by diamine oxidase and that is also secreted by enterochromaffin (*)-like cells.
Proliferations of these cells in the skin give rise to Darier's sign when rubbed and are known as urticaria pigmentosa. In  addition to germ-cell tumors and AML, the D816V ("D-eight-sixteen-V") mutation in the protein c-kit is often found with  overproliferation of these cells, which store and secrete chymase and tryptase. They release a substance that is broken  down by diamine oxidase and that is also secreted by enterochromaffin (*)-like cells. They are derived from CD34-positive  stem cells, like basophils, but mature in the tissue, where they may increase capillary permeability. They are stabilized by  cromolyn sodium, which is used to manage asthma. For 10 points, name these cells that respond to immunoglobulin E by  releasing histamine in an allergic reaction.
Proliferations of these cells in the skin give rise to Darier's sign when rubbed and are known as urticaria pigmentosa.
mast cells