Leukochromes and o-quinones are oxidation products of these chemicals.
One enzyme responsible for breaking down these chemicals has a notable V158M mutation that renders it heat-sensitive, and that enzyme is inhibited by enterocapone. Leukochromes and o-quinones are oxidation products of these chemicals. Cells that produce these chemicals take up a radioactive MIBG tracer, and their breakdown products include MHBG and vanillylmandelic acid. The ventral tegmental area and locus coeruleus produce these chemicals, which are degraded by the action of COMT. A tumor known for being ten percent bilateral and ten percent malignant periodically produces them, causing flushing and blood pressure spikes; that tumor is known as a pheochromocytoma. MAO is responsible for breaking these chemicals down, and they are produced by tyrosine hydroxylase in the chromaffin cells of the medulla of a certain gland. For 10 points, name these chemicals, some of which are secreted from the adrenal gland, which include dopamine, epinephrine and norepinephrine.
One enzyme responsible for breaking down these chemicals has a notable V158M mutation that renders it heat-sensitive, and that enzyme is inhibited by enterocapone.
Catecholamines