The defect in Ehler-Danlos syndrome results in impaired activity of lysyl oxidase, which is critical for (*) crosslinking strands of this molecule.
Fibroblast activation protein likely targets this molecule after its cleavage into three-quarter and one-quarter fragments by a certain enzyme. Evidence in support of a progressive maturation model of Golgi apparatus cisternae was provided by observing the transport of a precursor form of this molecule containing 200-residue propeptides at both ends. The defect in Ehler-Danlos syndrome results in impaired activity of lysyl oxidase, which is critical for (*) crosslinking strands of this molecule. Described by Ramachandran's Madras structure, this molecule commonly contains hydroxylysine and hydroxyproline, and typically forms a right-handed triple helix. For 10 points, name this protein found in extracellular matrix and connective tissue, the most abundant protein in mammals.
Fibroblast activation protein likely targets this molecule after its cleavage into three-quarter and one-quarter fragments by a certain enzyme.
collagen