In 1920, it was America's fifth most populous city.  
This city was home to the Peerlees Company, one of the "Three-Ps of Motordom".  In this city, Clarence Crane invented the Lifesaver hard candy.  A company based in this city publishes STIR Magazine, a magazine which "examines the many facets of color", appropriate since that company is Sherwin-Williams.  In 1920, it was America's fifth most populous city.  Arc-light inventor Charles Francis Brush was one of many Gilded Age tycoons to build mansions on (*) Millionaire's Row on Euclid Avenue in this city.  Chemist Samuel Andrews co-founded a company in this city that was broken in Esso and other companies in 1911.  A popular YouTube video purportedly posted by this city's tourism board points out "the place where there used to be industry".  George Washington Crile was one of the four doctors to found its namesake medical clinic.  For 10 points, Standard Oil was founded in what Ohio city?
This city was home to the Peerlees Company, one of the "Three-Ps of Motordom".  
Cleveland, Ohio