When molecules intended for this organelle are improperly tagged with mannose-6-phosphate they don't actually reach this organelle, which leads to (*) I-cell disease.
A deficiency in the enzyme alpha-NAGA causes a malfunction of this organelle called Schindler disease. Other problems with this organelle include Fabry's disease and Gaucher's disease.  When molecules intended for this organelle are improperly tagged with mannose-6-phosphate they don't actually reach this organelle, which leads to (*) I-cell disease. Malfunctions of this organelle itself can lead to Tay-Sachs disease, and it must maintain an acidic pH in order to function. For 10 points, name this organelle that digests macromolecules and cellular waste.
A deficiency in the enzyme alpha-NAGA causes a malfunction of this organelle called Schindler disease.
lysosome