In 1848, he ran for president on the Free Soil Party ticket.
This politician developed a political machine called the Albany Regency that was opposed by   William Seward. Andrew Jackson tried to appoint this person as Minister to Great Britain, but that  appointment was cancelled by Vice President John Calhoun, who broke a tie vote in the Senate.   Before that, this person was Jackson's secretary of state, and he later became Jackson's vice president.  In 1848, he ran for president on the Free Soil Party ticket. Name this president whose popularity was  weakened by the Panic of 1837, and who lost his re-election bid to William Henry Harrison.
This politician developed a political machine called the Albany Regency that was opposed by   William Seward.
Martin {Van Buren} [do not accept “Buren”]