Helicobacter pylori contains genes for homologs of this protein, allowing it to survive inside the stomach. Deficiency of its type II variety is autosomal recessive and results in osteopetrosis and cerebral calcification. It can be inhibited by acetazolamide, methazolamide, 
Helicobacter pylori contains genes for homologs of this protein, allowing it to survive inside the stomach. Deficiency of its type II variety is autosomal recessive and results in osteopetrosis and cerebral calcification. It can be inhibited by acetazolamide, methazolamide, and dichlorphenamide, all of which are used to treat glaucoma. In hippocampal cells, it regulates GABA theta activity, while renal tubule cells utilize it in conserving bases and parietal cells use it to generate HCl for stomach acid. Its discovery in 1932 made it the first known enzyme to utilize a zinc-containing active site. With one of the highest turnover numbers of any known enzyme, this is, FTP, what enzyme that rapidly converts carbon dioxide and water into bicarbonate and protons?
Helicobacter pylori contains genes for homologs of this protein, allowing it to survive inside the stomach.
carbonic anhydrase