Ficarro developed a "methyl-" version of this reaction for tagging peptides, and Schlater and Ziemnik's microwave catalysis was developed to accelerate the rate of this reaction. The use of KSF or a Dean-Stark apparatus may speed this reaction by eliminating water, driving the final step towards the products. In its final step, an oxonium atom loses water to produce the namesake product. Benzocain
Ficarro developed a "methyl-" version of this reaction for tagging peptides, and Schlater and Ziemnik's microwave catalysis was developed to accelerate the rate of this reaction. The use of KSF or a Dean-Stark apparatus may speed this reaction by eliminating water, driving the final step towards the products. In its final step, an oxonium atom loses water to produce the namesake product. Benzocain is a notable product of this reaction, in which a carboxylic acid and an alcohol are refluxed in the presence of an acid catalyst. FTP, name this esterification reaction named for a German chemist.
Ficarro developed a "methyl-" version of this reaction for tagging peptides, and Schlater and Ziemnik's microwave catalysis was developed to accelerate the rate of this reaction.
Fischer Esterification