Drug discovery research e
Drug discovery research employs a synthesis that produces alpha-phosphonate examples of this functionality from a carbonyl, a hydrophosphoryl compound, and a primary one of these. A test for this functionality, which can discern between their degrees of substitution, employs aqueous sodium hydroxide and benzenesulfonyl chloride and is named for Hinsburg. CO2 is released upon the addition of hydrazoic acid through an isocyanate intermediate in one reaction to form them. PPh3 is used to reduce azides to this functionality in the Staudinger ligation. The best known synthesis of these compounds reacts primary alkyl halides with potassium phthalimide, and is named for Gabriel. For 10 points, name this functionality whose members possess a nitrogen with three single bonds to substituents.
Drug discovery research employs a synthesis that produces alpha-phosphonate examples of this functionality from a carbonyl, a hydrophosphoryl compound, and a primary one of these.
 amines