In an October, 1997 JCE article, Parquet and Lin outlined a microwave-assisted version of this procedure that creates a reagent in situ by irradiation of isatin. This reaction is analogous to hydroxylamine-mediated oxime synthesis. It is sometimes cited as only its second step, which is usually catalyzed by an alkali ethoxide or potassium hydroxide, but that second step cannot proceed without an initial hydroxone formation by the carbonyl-containing reactants. It is now rarely performed since it requires extremely dangerous heating of hydrazine in the presence of ketones or aldehydes. FTP, nam
In an October, 1997 JCE article, Parquet and Lin outlined a microwave-assisted version of this procedure that creates a reagent in situ by irradiation of isatin. This reaction is analogous to hydroxylamine-mediated oxime synthesis. It is sometimes cited as only its second step, which is usually catalyzed by an alkali ethoxide or potassium hydroxide, but that second step cannot proceed without an initial hydroxone formation by the carbonyl-containing reactants. It is now rarely performed since it requires extremely dangerous heating of hydrazine in the presence of ketones or aldehydes. FTP, name this organic reduction of ketones or aldehydes to corresponding alkanes, named for German and Russian chemists.
In an October, 1997 JCE article, Parquet and Lin outlined a microwave-assisted version of this procedure that creates a reagent in situ by irradiation of isatin.
Wolff-Kishner reduction