These compounds become isocynates via a hydroxamic acid intermediate in the Lossen rearrangement, and undergo alpha-hydroxylation in the Chan reaction. Methods of synthesizing them include a migratory insertion which uses MCPBA on a ketone, and carboxylates of any length can be created using the synthesis named for the malonic type of them. Cyclic ones are known as lactones, and in addition to the aforementioned Baeyer-Vi
These compounds become isocynates via a hydroxamic acid intermediate in the Lossen rearrangement, and undergo alpha-hydroxylation in the Chan reaction. Methods of synthesizing them include a migratory insertion which uses MCPBA on a ketone, and carboxylates of any length can be created using the synthesis named for the malonic type of them. Cyclic ones are known as lactones, and in addition to the aforementioned Baeyer-Villiger oxidation, they can be synthesized under reflux conditions in a reaction named for Fischer that uses an acid and an alcohol. Also undergoing the Claisen condensation when reacted with a base. FTP, name these organic compounds responsible for the sweet smell of fruit.
These compounds become isocynates via a hydroxamic acid intermediate in the Lossen rearrangement, and undergo alpha-hydroxylation in the Chan reaction.
esters