Avidity is a form of this concept resulting from polyvalency, and Levinthal's paradox assumes that one process governed by it proceeds via a sequential rather than parallel me
Avidity is a form of this concept resulting from polyvalency, and Levinthal's paradox assumes that one process governed by it proceeds via a sequential rather than parallel mechanism. The KNF model describes a sequential induced fit pattern for it, which accounts for the negative form of this phenomenon, while the WMC model proposes molecules changing conformation from a T-state to an R-state. It is quantified by the Hill coefficient, which for myoglobin is 1.0 and for hemoglobin is 2.8. It is typically exemplified by deoxyhemglobin's weaker affinity for oxygen versus oxyhemoglobin. For 10 points, name this type of allostery in which the binding of a ligand to a molecule affects the affinity of subsequent ligands to that molecule.
Avidity is a form of this concept resulting from polyvalency, and Levinthal's paradox assumes that one process governed by it proceeds via a sequential rather than parallel mechanism.
cooperativity [prompt on early "allostery" or similar answers]