The Kidd glycoproteins present on their surface act as urea transporters. Spectrin and ankyrin are found in the cytoskeletal network of these cells and antibodies on their surface are detected by the direct Coombs test. They express high levels of CD47, which prevents phagocytosis by macrophages in the spleen, and kidneys release EPO which stimulate the production of these. Excess production of them results in polycythemia, and their count is depressed in anemia. Produced in the bone marrow, they are biconcave and lack nuclei. For 10 points, identify these cells that contain hemoglobin, and help transport oxygen to tissues.
The Kidd glycoproteins present on their surface act as urea transporters. Spectrin and ankyrin are found in the cytoskeletal network of these cells and antibodies on their surface are detected by the direct Coombs test. They express high levels of CD47, which prevents phagocytosis by macrophages in the spleen, and kidneys release EPO which stimulate the production of these. Excess production of them results in polycythemia, and their count is depressed in anemia. Produced in the bone marrow, they are biconcave and lack nuclei. For 10 points, identify these cells that contain hemoglobin, and help transport oxygen to tissues.
The Kidd glycoproteins present on their surface act as urea transporters.
red blood cells [or RBCs; or erythrocytes]