RANKL and M-CSF can promote the transdifferentiation of osteoclasts into this cell type.  Their namesake grabbing non-integrin protein promotes their interaction with ICAM-3 receptors.  Steinman and Cohn first identified them in Mishell-Dutton culture.  Subtypes of these cells include the plasmacytoid and follicular classes, while another subtype p
RANKL and M-CSF can promote the transdifferentiation of osteoclasts into this cell type.  Their namesake grabbing non-integrin protein promotes their interaction with ICAM-3 receptors.  Steinman and Cohn first identified them in Mishell-Dutton culture.  Subtypes of these cells include the plasmacytoid and follicular classes, while another subtype possess Birbeck granules, are found in the epidermis, and are called Langerhans cells.  These immune cells are capable of cross-presentation of MHC-1-antigen complexes from other cells, and this type of cell can be pre-incubated with antigen and used as a vaccine.  Unlike macrophages and lymphocytes, these MHC-2-expressing cells can activate both helper AND na?e T cells.  FTP, name this class of antigen-presenting cells named for their branching pseudopods which resemble a type of neural structure.
RANKL and M-CSF can promote the transdifferentiation of osteoclasts into this cell type.  
dendritic cells