A 2010 study showed that G9a, which methylates one of these proteins, is downregulated after cocaine use. In 1990 the Grunstein lab at UCLA caused yeast mating efficiency to decrease by replacing a lysine at position 16 of one of these proteins with either arginine, glycine, or glutamine. That study showed that mutations in SIR3 could partially allow mutated forms of these proteins to repress the transcription of HML-alpha and HMR-alpha. The lysines on the tails of these proteins are reversibly acetylated by proteins such as GCN5. An octamer consisting of two each of the 2A, 2B, 3, and 4 members of this family of prot
A 2010 study showed that G9a, which methylates one of these proteins, is downregulated after cocaine use. In 1990 the Grunstein lab at UCLA caused yeast mating efficiency to decrease by replacing a lysine at position 16 of one of these proteins with either arginine, glycine, or glutamine. That study showed that mutations in SIR3 could partially allow mutated forms of these proteins to repress the transcription of HML-alpha and HMR-alpha. The lysines on the tails of these proteins are reversibly acetylated by proteins such as GCN5. An octamer consisting of two each of the 2A, 2B, 3, and 4 members of this family of proteins forms the protein core of a nucleosome. For 10 points, name this family of proteins around which DNA is packed in chromatin.
A 2010 study showed that G9a, which methylates one of these proteins, is downregulated after cocaine use.
histones