When it involves a silyl enol ether, it is known as the Mukaiyama reaction. The first step is an acid-base reaction that removes an alpha-hydrogen from one of the reactants, forming an enolate. When this is followed by an aldol condensation, sometimes the ethoxide can combine with the ketone to form an ether, but generally bicyclic ring systems are formed in a process called Robinson annulation. The reaction donors are usually active methylenes like nitroalkanes and malonates. FTP, name this reaction involving a 1,4-addition of a carbanion to an alpha, beta-unsaturated carbonyl compound, most often used to create carbon-carbon bonds.
When it involves a silyl enol ether, it is known as the Mukaiyama reaction. The first step is an acid-base reaction that removes an alpha-hydrogen from one of the reactants, forming an enolate. When this is followed by an aldol condensation, sometimes the ethoxide can combine with the ketone to form an ether, but generally bicyclic ring systems are formed in a process called Robinson annulation. The reaction donors are usually active methylenes like nitroalkanes and malonates. FTP, name this reaction involving a 1,4-addition of a carbanion to an alpha, beta-unsaturated carbonyl compound, most often used to create carbon-carbon bonds.
When it involves a silyl enol ether, it is known as the Mukaiyama reaction.
Michael addition or Michael reaction