In Arabidopsis, mutations in genes containing NBS-LRR motifs, such as R-genes, promote this phenomenon.  In humans, IDO-mediated ky-nu-ren-ine production and tryptophan depletion promotes this condition, and helminths induce this process by secreting cystatins, which inhibit
In Arabidopsis, mutations in genes containing NBS-LRR motifs, such as R-genes, promote this phenomenon.  In humans, IDO-mediated ky-nu-ren-ine production and tryptophan depletion promotes this condition, and helminths induce this process by secreting cystatins, which inhibit cathepsins and other proteases.  Stress-induced phosphorylation of alpha-b-crystallin can lead to the breakdown of this process, causing the destruction of myelin.  Fas-ligand-mediated apoptosis enforces this condition in tissues like the cornea and brain.  In the "central" type of this process, anergy is induced in T-cells with very high affinities for self MHC, and it is pharmacologically induced in recipients of organ transplants.  For 10 points, name this condition in which the presence of an antigen fails to activate a defense response.
In Arabidopsis, mutations in genes containing NBS-LRR motifs, such as R-genes, promote this phenomenon.  
immune tolerance (accept immunotolerance, immune suppression, or immunosuppression at any point; accept disease tolerance on the plants clue, but peripheral tolerance or central tolerance are not correct)