One variation on this reaction proceeds via the Smiles rearrangement. Poly-?leucine acts as a catalyst in an epoxidation reaction named after Colonna and this reaction's namesake. Keck et al. demonstrated that when samarium (II) iodide is used in the second step of this reaction, deuterium from a deuterated methanol solvent is not incorporated into the final product, in contrast to the use of a sodium amalgam in that second step. A variant that e
One variation on this reaction proceeds via the Smiles rearrangement. Poly-?leucine acts as a catalyst in an epoxidation reaction named after Colonna and this reaction's namesake. Keck et al. demonstrated that when samarium (II) iodide is used in the second step of this reaction, deuterium from a deuterated methanol solvent is not incorporated into the final product, in contrast to the use of a sodium amalgam in that second step. A variant that eliminates that second step is partially named after Kocienski. An alcohol intermediate is formed in its first step via the addition of a phenyl sulfone to an aldehyde or ketone. For 10 points, name this alternative to the Schlosser modification of the Wittig reaction for producing (E)-alkenes.
One variation on this reaction proceeds via the Smiles rearrangement.
Julia-Lythgoe Olefination [accept Julia-Kocienski Olefination before "second," but do not accept or prompt afterwards]