This molecule is found in high concentrations in the basal nucleus of Meynert. One class of receptors for it is antagonized by the likes of mamba toxin and gallamine and contains five different members based on the alpha subunit of their associated G proteins.  Another class of receptors for it is ionotropic and is targeted by auto-immune antibodie
This molecule is found in high concentrations in the basal nucleus of Meynert. One class of receptors for it is antagonized by the likes of mamba toxin and gallamine and contains five different members based on the alpha subunit of their associated G proteins.  Another class of receptors for it is ionotropic and is targeted by auto-immune antibodies in myasthenia gravis. Its muscarinic receptors bind it at the end of parasympathetic nerves, while the nictonic receptors for this molecule, whose release is blocked by botulinum toxin, are found on muscle cells. For 10 points, name this neurotransmitter depleted in Alzheimer's disease, which is cleaved by its namesake -esterases.
This molecule is found in high concentrations in the basal nucleus of Meynert.
acetylcholine