Rett syndrome has been as
Rett syndrome has been associated with hypermodification of certain classes of these proteins. During spermatogenesis, they are replaced by the arginine-rich protamines, which are necessary for sperm head condensation. The largest of these, class 1, links octameric units of the other four classes. These proteins are rich in positively charged amino acids such as lysine, which is often modified in them by acetyl groups. Four types of these form part of a unit spanning 146 base pairs called a nucleosome, which is key for the supercoiling of DNA. For 10 points, name these proteins around which DNA wraps to form chromatin.
Rett syndrome has been associated with hypermodification of certain classes of these proteins.
histones