These molecules have been found to rescue photoreceptors from degeneration in models of retinitis pigmentosa, and one example of them has been implicated in many leukemias as a downregulator of p16-INK4a. "Water wires" folded into these molecules may serve as proton shuttles that enhance their activity. The only one of these that requires a small-molecule activator to function regulates the production of glucosamine-6-pho
These molecules have been found to rescue photoreceptors from degeneration in models of retinitis pigmentosa, and one example of them has been implicated in many leukemias as a downregulator of p16-INK4a. "Water wires" folded into these molecules may serve as proton shuttles that enhance their activity. The only one of these that requires a small-molecule activator to function regulates the production of glucosamine-6-phosphate. Another notable example of these has G5, G8, and G12 motifs key to its function in a magnesium ion in its active site. These molecules can catalyze Diels-Alder reactions in vivo and hydrolyze their own phosphodiester bonds. For 10 points, the spliceosome might be and "Hammerhead" is one example of what RNA molecules that possess catalytic ability?
These molecules have been found to rescue photoreceptors from degeneration in models of retinitis pigmentosa, and one example of them has been implicated in many leukemias as a downregulator of p16-INK4a.
{ribozymes} [accept {RNA enzyme} before the {giveaway}; accept {catalytic RNA} before the {giveaway}]