The p63 transcriptional target Perp is a primary regulator of the assembly of these structures. The protein tyrosine phosphatase inhibitor pervanadate has been found to stabil
The p63 transcriptional target Perp is a primary regulator of the assembly of these structures. The protein tyrosine phosphatase inhibitor pervanadate has been found to stabilize these patch-like structures, and protein kinase C causes a switch from their low- to high-affinity state. ERBIN, a protein governing cell polarity, binds armadillo and armadillo homolog proteins associated with these structures. Along with a similar structure whose major functional protein is integrin, they associate with plectins. Plakoglobins link these structures' major constituent proteins, cadherins. Pemphigus vulgaris results when antibodies attack proteins in these structures on keratinocytes, causing blistering as the upper layers of the epidermis to separate from the basal layers. For 10 points, name this type of cell-cell junction that appears primarily in cardiac and epithelial tissue.
The p63 transcriptional target Perp is a primary regulator of the assembly of these structures.
{desmosomes} [or {macula adherens}; or {spot} junction; do not accept or prompt on "{adherens junction}"; do not accept or prompt on "{hemidesmosome}"]