The shelterin complex protects these entities from non-homologous end joining, and they can form G-quadraplexes with bonding between G and C sequences. The TRAP assay is used to study the activity of enzymes associated with them. Disruptions in TFR2 binding to these regions results in damage signaling. The RNA-containing enzyme that extends these was discovered by Blackburn and is responsible for the characteristic repeat of these entities. Their shortening causes the end-replication problem, which leads to the Hayflick limit on eukaryotic cell division. For 10 points, name this region found at the end of linear chromosomes.
The shelterin complex protects these entities from non-homologous end joining, and they can form G-quadraplexes with bonding between G and C sequences. The TRAP assay is used to study the activity of enzymes associated with them. Disruptions in TFR2 binding to these regions results in damage signaling. The RNA-containing enzyme that extends these was discovered by Blackburn and is responsible for the characteristic repeat of these entities. Their shortening causes the end-replication problem, which leads to the Hayflick limit on eukaryotic cell division. For 10 points, name this region found at the end of linear chromosomes.
The shelterin complex protects these entities from non-homologous end joining, and they can form G-quadraplexes with bonding between G and C sequences.
{telomeres}