MicroRNAs produced from this organism arise from the BHRF-1 and BART regions of its genome. This organism produces the protein BARF1, which binds M-CSF, and LMP-1, which is often expressed in Reed-Sternberg cells. Infection by this organism can be diagnosed using the heterophile antibody test, and the development of cells with a starry sky appearance can result from chronic infection with this organism. This organism binds to CD21 and can hasten the development of a translocation between chromosomes 8 and 14, resulting in the fusion of an immunoglobulin gene locus to t
MicroRNAs produced from this organism arise from the BHRF-1 and BART regions of its genome. This organism produces the protein BARF1, which binds M-CSF, and LMP-1, which is often expressed in Reed-Sternberg cells. Infection by this organism can be diagnosed using the heterophile antibody test, and the development of cells with a starry sky appearance can result from chronic infection with this organism. This organism binds to CD21 and can hasten the development of a translocation between chromosomes 8 and 14, resulting in the fusion of an immunoglobulin gene locus to the gene for c-myc. This organism transforms B lymphocytes into lymphoblasts and predisposes infected people to develop nasopharyngeal carcinoma and Burkitt lymphoma. Manifestations of a disease caused by this virus include posterior cervical lymphadenopathy, an enlarged spleen, and fatigue. For 10 points, name this herpesvirus that causes infectious mononucleosis.
MicroRNAs produced from this organism arise from the BHRF-1 and BART regions of its genome.
{Epstein}-{Barr virus} or {EBV} [accept {human herpesvirus}-{4}]