The Vilsmeier reaction achieves the same effect as this reaction by proceeding through an iminium intermediate. It is replaced by the Gatterman-Koch reaction with carbon monoxide, and a two-step process beginning with it replaces a related reaction that, unless the starting material is tertiary, will lead to rearrangement. Moreover, that related reaction generates a more reactive product, leading to polyalkylation, so instead this reaction is followed by Clemmensen or Wolff-Kishner reduction. FTP, identify this reaction, catalyzed by Lewis acids like aluminum trichlori
The Vilsmeier reaction achieves the same effect as this reaction by proceeding through an iminium intermediate. It is replaced by the Gatterman-Koch reaction with carbon monoxide, and a two-step process beginning with it replaces a related reaction that, unless the starting material is tertiary, will lead to rearrangement. Moreover, that related reaction generates a more reactive product, leading to polyalkylation, so instead this reaction is followed by Clemmensen or Wolff-Kishner reduction. FTP, identify this reaction, catalyzed by Lewis acids like aluminum trichloride, a substitution reaction that links a terminal carbonyl compound to a benzene ring.
The Vilsmeier reaction achieves the same effect as this reaction by proceeding through an iminium intermediate.
{Friedel}-{Crafts} acylation