This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction. It has recently been found to work in DMSO with potassi
This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction. It has recently been found to work in DMSO with potassium tert-butoxide and hydrazine at room temperature, but is more commonly used with hydrazine to form a hydrazone that is then heated with concentrated sodium hydroxide in diethylene glycol. FTP, identify this reduction reaction that converts a carbonyl group to a methylene group named after its two co-discoverers.
This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction.
{Wolff-Kishner} reduction