First described in 1881 by Claparede and its namesake discoverer, this organic chemistry reaction is catalyzed by enzymes such as malate synthase and ATP citrate lyase. An alkoxide removes the acidic alpha-hydrogen from an ester, with the ester enolate undergoing a nucleophi
First described in 1881 by Claparede and its namesake discoverer, this organic chemistry reaction is catalyzed by enzymes such as malate synthase and ATP citrate lyase. An alkoxide removes the acidic alpha-hydrogen from an ester, with the ester enolate undergoing a nucleophilic substitution reaction to form a 1  tetrahedral intermediate with another ester. The alkoxide leaving group is expelled and a beta-keto-ester results. FTP, what is this reaction, the ester analogue of the aldol condensation?
First described in 1881 by Claparede and its namesake discoverer, this organic chemistry reaction is catalyzed by enzymes such as malate synthase and ATP citrate lyase.
Claisen condensation