Their infection and replication processes are still mysterious, with the "P
Their infection and replication processes are still mysterious, with the "Protein X" hypothesis suggesting that an unidentified cellular protein causes the PrPC and PrPSc to form a complex.* Their existence was first proposed in the 1960s in connection with several TSE's, but it was not until 1982 that they were discovered by Stanley Prusiner, who won the 1997 Nobel Price in Medicine for that discovery. FTP, name these infectious protein structures which are thought to be responsible for scrapie, kuru, and mad cow's disease, among other transmissible spongiform encephalopathy diseases.
Their infection and replication processes are still mysterious, with the "Protein X" hypothesis suggesting that an unidentified cellular protein causes the PrPC and PrPSc to form a complex.
Prions or Proteinaceous Infection Particles