Samuel C. Lister discovered a method for using the waste made in the production of this substance.  Thomas and John Lombe built the first industrial facility for processing this substance in England. In the late  1800s, Patterson, NJ was the largest 
Samuel C. Lister discovered a method for using the waste made in the production of this substance.  Thomas and John Lombe built the first industrial facility for processing this substance in England. In the late  1800s, Patterson, NJ was the largest producer of this substance in the U.S. . The Byzantine Empire learned to  produce this substance through the effort of two monks with hollowed out staffs. Dr. Randy Lewis is the  godfather of the science of making a variant of this material using goats. This substance was replaced in many  applications by a discovery of Wallace H. Carothers . Joseph Marie Jacquard developed a machine to automate the  assembly of goods made using this material. The commercial production of this material relies on Bombyx mori  and  Mulberry leaves. Legendarily, Leizu was the first to learn how to master this material after a cocoon fell in her tea.  For 10 points, name this fiber that lends its name to a historical commercial route in Central Asia.
Samuel C. Lister discovered a method for using the waste made in the production of this substance.  
silk