This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction. It has recently been found to work in DMSO with potassium tert-butoxide and hydrazine at room temperature
This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction. It has recently been found to work in DMSO with potassium tert-butoxide and hydrazine at room temperature, but is more commonly used with hydrazine to form a hydrazone that is then heated with concentrated sodium hydroxide in diethylene glycol. FTP, identify this reduction reaction that converts a carbonyl group to a methylene group named after its two co-discoverers.
This reaction cannot be performed in the presence of groups sensitive to a concentrated base, unlike the analogous Raney nickel desulfurization and Clemmensen reduction.
{Wolff-Kishner} reduction