This reaction is similar to the Blanc Reaction, which typically creates chloro-methylated compounds, and it makes ready use of ionic liquids. It can be extended to apply to coumarins, and the same type of product is created by a Fries Rearrangement. Sometimes performed in connection with a Prins cyc
This reaction is similar to the Blanc Reaction, which typically creates chloro-methylated compounds, and it makes ready use of ionic liquids. It can be extended to apply to coumarins, and the same type of product is created by a Fries Rearrangement. Sometimes performed in connection with a Prins cyclization, it must be carried out with more than one equivalent of Al-Cl3 to avoid complexing, and one variant of it is often employed as a two-step process ending in reduction of the carbonyl group that is attached. FTP, name this reaction which can be an acylation or an alkylation, depending on what type of group is added to the benzene ring, named for two chemists.
This reaction is similar to the Blanc Reaction, which typically creates chloro-methylated compounds, and it makes ready use of ionic liquids.
{Friedel-Crafts} reaction or alkylation or acylation