Heathcock developed two one-pot variations of this reaction, one of which cuts back on polymerization using beta-chloroketones. Napthalene derivatives are synthesized using a variation of this reaction which uses a compound methylene sulfoxide ortho to an ester, while another variation uses dichloro- cis-2-butene. Using a pentadienone in this reaction can synthesize a compound named for Hajos and Parrish, while it can more famously be used to create a compound used in several terpene and steroid syntheses, named for Wieland and Meischer. The aforementioned variations are named for Hauser and Wichterle, the former which has a Dieckmann condensation instead of the usual second step. Using a methyl vinyl ketone, for ten points, name this reaction used to create alpha-beta unsaturated cyclic ketones, which consists of a Michael addition followed by an aldol condensation.
Heathcock developed two one-pot variations of this reaction, one of which cuts back on polymerization using beta-chloroketones. Napthalene derivatives are synthesized using a variation of this reaction which uses a compound methylene sulfoxide ortho to an ester, while another variation uses dichloro- cis-2-butene. Using a pentadienone in this reaction can synthesize a compound named for Hajos and Parrish, while it can more famously be used to create a compound used in several terpene and steroid syntheses, named for Wieland and Meischer. The aforementioned variations are named for Hauser and Wichterle, the former which has a Dieckmann condensation instead of the usual second step. Using a methyl vinyl ketone, for ten points, name this reaction used to create alpha-beta unsaturated cyclic ketones, which consists of a Michael addition followed by an aldol condensation.
Heathcock developed two one-pot variations of this reaction, one of which cuts back on polymerization using beta-chloroketones.
{Robinson} annulation