These cells appear to be the cause of Gorham-Stout syndrome. TheY secrete cathepsin-K and sit in cav
These cells appear to be the cause of Gorham-Stout syndrome. TheY secrete cathepsin-K and sit in cavities called Howship's lacunae, attaching to their target using integrins like alpha v beta three. RANK ligand, also known as TNF-related activation-induced cytokine, is essential to their formation, and they function by using carbonic anhydrase to pump out protons, which helps the target decay into a certain cation, as well as phosphoric acid and carbonic acid. Prostaglandin E and vitamin D3 oddly lack receptors on these cells. Parathyroid hormone increases the number of these TRAP-positive differentiated macrophages, while calcitonin inhibits their activity. FTP, name these cells whose role it is to resorb bone, which are often contrasted with osteoblasts.
These cells appear to be the cause of Gorham-Stout syndrome.
{osteoclasts}