The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations. Its typical first step sees reaction of cyclohexanone with a secondary amine like pyrrolidin to form the nucleophile – that nucleophile, in a Michael-type reaction, proceeds to attack an alpha-beta-unsaturated carbonyl compound, and after hydrolysis, the end result is a 1,5-dic
The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations. Its typical first step sees reaction of cyclohexanone with a secondary amine like pyrrolidin to form the nucleophile – that nucleophile, in a Michael-type reaction, proceeds to attack an alpha-beta-unsaturated carbonyl compound, and after hydrolysis, the end result is a 1,5-dicarbonyl compound. FTP, name this reaction which uses an enamine rather than an enolate to perform alkylation, and is named for a Belgian chemist.
The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations.
{Stork} enamine reaction