Much like the reovirus 1, these agents have fibers which exhibit a triple beta spiral motif. Those fibers protrude from the penton base protein present in their capsids and interact with integrins alpha v beta 3 and alpha v beta 5, which facilitates their internalization. An avian variant of these agents causes the Marble Spleen disease, and systems utilizing these which maintain only the 5' and 3' ITR sequences are called the "gutless" or "helper dependent" versions of these. They recognize the CAR protein present on the cell surface of their hosts. A virus often found in cells simultaneously infected with these viruses is known as a virus "associated" with these viruses; those "associated" viruses are prime candidates for gene therapy vectors. For 10 points, identify these infectious agents which got their name because they were first discovered in adenoid tissue.
Much like the reovirus 1, these agents have fibers which exhibit a triple beta spiral motif. Those fibers protrude from the penton base protein present in their capsids and interact with integrins alpha v beta 3 and alpha v beta 5, which facilitates their internalization. An avian variant of these agents causes the Marble Spleen disease, and systems utilizing these which maintain only the 5' and 3' ITR sequences are called the "gutless" or "helper dependent" versions of these. They recognize the CAR protein present on the cell surface of their hosts. A virus often found in cells simultaneously infected with these viruses is known as a virus "associated" with these viruses; those "associated" viruses are prime candidates for gene therapy vectors. For 10 points, identify these infectious agents which got their name because they were first discovered in adenoid tissue.
Much like the reovirus 1, these agents have fibers which exhibit a triple beta spiral motif.
{adenovirus} [or {adenoviridae}]