Several of these proteins contain the homologous nine-residue sequence R-X-X-L-G-X-I-G-D/N, known as the "destruction box," and a high concentration of one of them can competitively inhibit its own APC-mediated polyubiquitination. The TAR sequence of HIV binds to the Tat protein as well as one of these proteins. In Saccharomyces cerevisiae, three of them can bind to their namesake (*) dependent ki
Several of these proteins contain the homologous nine-residue sequence R-X-X-L-G-X-I-G-D/N, known as the "destruction box," and a high concentration of one of them can competitively inhibit its own APC-mediated polyubiquitination. The TAR sequence of HIV binds to the Tat protein as well as one of these proteins. In Saccharomyces cerevisiae, three of them can bind to their namesake (*) dependent kinases to form the S phase-promoting factor. The D1 type of these proteins can function as oncoproteins, while the B type is most active during mitosis. For 10 points, identify this class of proteins that regulate the cell cycle, so named because their concentration oscillates as cells move through that cycle.
Several of these proteins contain the homologous nine-residue sequence R-X-X-L-G-X-I-G-D/N, known as the "destruction box," and a high concentration of one of them can competitively inhibit its own APC-mediated polyubiquitination.
{cyclin}s [accept {Cyclin B} before “HIV”] (5) [DW]