The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations. Its typical first step sees reaction of cyclohexanone with a secondary amine like pyrrolidin to form the nucleophile – that nucleophile, in a Michael-type reaction, proceeds to attack an alpha-beta-unsaturated carbonyl compound, and after hydrolysis, the end result is a 1,5-dicarbonyl compound. FTP, name this reaction which uses an enamine rather than an enolate to perform alkylation, and is named fo
The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations. Its typical first step sees reaction of cyclohexanone with a secondary amine like pyrrolidin to form the nucleophile – that nucleophile, in a Michael-type reaction, proceeds to attack an alpha-beta-unsaturated carbonyl compound, and after hydrolysis, the end result is a 1,5-dicarbonyl compound. FTP, name this reaction which uses an enamine rather than an enolate to perform alkylation, and is named for a Belgian chemist.
The namesake of this reaction also gives his name to a hypothesis with Eschenmoser regarding the stereochemistry of cationic polyene cyclizations.
{Stork} enamine reaction