One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice. Genes involved in this process are upregulated by the cooperation between HNF-4-alpha, PGC-1, and FOXO1. Both glucagon and cortisol upregulate this process, which is inhibited by the biguanide AMP kinase inhibitor metformin. This pathway is inhibi
One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice. Genes involved in this process are upregulated by the cooperation between HNF-4-alpha, PGC-1, and FOXO1. Both glucagon and cortisol upregulate this process, which is inhibited by the biguanide AMP kinase inhibitor metformin. This pathway is inhibited by fructose-2,6-bisphosphate, and two GTP are used by PEP carboxykinase in the first of its (*) three bypass steps. This process, which occurs in the liver after 12 hours of fasting, uses two pyruvate molecules as the input, reversing a different pathway. For 10 points, name this pathway which synthesizes new glucose from smaller precursors.
One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice.
gluconeogenesis