The pneumatic assistance model and pooling model attempt to explain this technique. There is an apparent fluence threshold in this technique due to there being an energy requirement for widespread ablation, and the efficiency in this technique is dependent on fluence and not irradiance. A two-pulse phenomenon in this technique was discovered by Vertes and Knochenmuss. Karas et all proposed that neutral clusters in this technique release ions during an ablative procedure,
The pneumatic assistance model and pooling model attempt to explain this technique. There is an apparent fluence threshold in this technique due to there being an energy requirement for widespread ablation, and the efficiency in this technique is dependent on fluence and not irradiance. A two-pulse phenomenon in this technique was discovered by Vertes and Knochenmuss. Karas et all proposed that neutral clusters in this technique release ions during an ablative procedure, in what is known as the Lucky Survivors Model. A 1:1 mixture of DHB and alpha-cyano-4-hydroxy-cinnamic acid is a universal substrate for this procedure, whose other substrates include sialic acid and 4-nitroaniline. This technique doesn't fragment the ions and is overall a softer method than electrospray ionization, and like ESI this technique is combined with time-of-flight analyzers for peptide mass fingerprinting. For 10 points, name this technique in which a sample about to undergo mass spectrometry in which a molecule is stuck to a crystalline matrix by a laser.
The pneumatic assistance model and pooling model attempt to explain this technique.
MALDI [or Matrix-assisted Laser Desorption Ionization]