The biogenesis of this organelle is regulated by transcription factor EB and Rab7. One disease affecting these organelles causes xanthomatosis and adrenal gland calcification, while another is marked by tissue-paper macrophages and Erlenmeyer flask deformity in the femur. Th
The biogenesis of this organelle is regulated by transcription factor EB and Rab7. One disease affecting these organelles causes xanthomatosis and adrenal gland calcification, while another is marked by tissue-paper macrophages and Erlenmeyer flask deformity in the femur. Those diseases are caused by mutations in LAL and glucocerebrosidase and are named for Wolman and Gaucher. I-cell disease causes these organelles to be empty due to a mutation in the (*) M6P receptor, while another namesake storage disease of this organelle is similar to Sandhoff's disease and is caused by a mutation in HEXA. These organelles have V-type ATPases in their membranes and contain sulfatases, lipases, and proteases stored at pH 4.5. For 10 points, name these organelles that degrade waste products in the cell.
The biogenesis of this organelle is regulated by transcription factor EB and Rab7.
lysosome