One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice. Genes involved in this process are upregulated by the cooperation between HNF-4-alpha, PGC-1, and FOXO1. Both glucagon and cortisol upregulate this process, which is inhibited by the biguanide AMP kinase inhibitor metformin. This pathway is inhibited by fructose-2,6-bisphosphate, and two GTP are used by PEP carboxykinase in the first of its (*) three bypass steps. This process, which occurs in the liver after 12 hours of fasting, uses two pyruvate molecules as the input, reversing a different pathway. For 10 points, 
One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice. Genes involved in this process are upregulated by the cooperation between HNF-4-alpha, PGC-1, and FOXO1. Both glucagon and cortisol upregulate this process, which is inhibited by the biguanide AMP kinase inhibitor metformin. This pathway is inhibited by fructose-2,6-bisphosphate, and two GTP are used by PEP carboxykinase in the first of its (*) three bypass steps. This process, which occurs in the liver after 12 hours of fasting, uses two pyruvate molecules as the input, reversing a different pathway. For 10 points, name this pathway which synthesizes new glucose from smaller precursors.
One enzyme in this pathway is inactivated by hydrazine sulfate, and mutation of the rate-controlling enzyme in this process creates metabolic supermice.
gluconeogenesis