Destroyed by the spleen and produced in the bone marrow, they are biconcave and do not have nuclei.
Membrane proteins in these entities called glycophorins have high levels of sialic acid residues, which can lead to the formation of stacks of these entities called rouleaux. Abnormal deposits of DNA in them are called Howell-Jolly bodies, and their high surface expression of CD47 protects them from phagocytosis. They are overproduced in (*) polycythemia, while the substitution of valine for glutamic acid leads to a notable mutation in their structure. Destroyed by the spleen and produced in the bone marrow, they are biconcave and do not have nuclei. For 10 points, name these cells whose hemoglobin molecules carry oxygen to tissue, often contrasted with the white cells of the immune system.
Membrane proteins in these entities called glycophorins have high levels of sialic acid residues, which can lead to the formation of stacks of these entities called rouleaux.
{erythrocytes} or {red blood cells}