A variant of this reaction in which aryl aldehydes are oxidized is named for Dakin.
Members of the Aspergillus genus catalyze this reaction on de-methyl-sterigmato-cystin to produce aflatoxin. The anti-tubercular agent ethionamide is converted into its active form by an enzyme that catalyzes this reaction. Doerring and Dorfman's early experiments ruled out the dioxirane intermediate hypothesized by the namesakes of this reaction. In its first step, the carbonyl oxygen is protonated, followed by a nucleophilic attack of the carbonyl carbon by the oxidizing agent. In the resulting tetrahedral intermediate, the more highly substituted carbon migrates toward the oxygen atom, leading to a carboxylic acid product in a mechanism that was described by Rudolf Criegee. A variant of this reaction in which aryl aldehydes are oxidized is named for Dakin. For 10 points, name this reaction in which a peroxy-acid, like mCPBA, is used to convert a ketone into an ester, an oxidation reaction named for two chemists, one Swiss and one German.
Members of the Aspergillus genus catalyze this reaction on de-methyl-sterigmato-cystin to produce aflatoxin.
Baeyer-Villiger oxidation [or Baeyer-Villiger rearrangement]