Symptoms include jerky movement, ataxia, speech impairment, and dementia, leading to hallucinations and personality changes within one year.
Investigations for diagnosing this disease include searching the EEG for triphasic spikes, testing the spinal fluid for 14-3-3 protein, and checking an MRI for high signal intensity in the caudate nucleus and putamen bilaterally on T2-weighted images, but the only definitive diagnosis is made from biopsy of tonsils or the brain. Symptoms include jerky movement, ataxia, speech impairment, and dementia, leading to hallucinations and personality changes within one year. Characterized by cavitating lesions in the brain, the disease is incurable. Acquired by one person in a million, including anatomic pathologists and choreographer George Balanchine, FTP, what is this transmissible spongiform encephalopathy in humans caused by a prion?
Investigations for diagnosing this disease include searching the EEG for triphasic spikes, testing the spinal fluid for 14-3-3 protein, and checking an MRI for high signal intensity in the caudate nucleus and putamen bilaterally on T2-weighted images, but the only definitive diagnosis is made from biopsy of tonsils or the brain.
Creutzfeldt-Jakob Disease (accept CJD; also accept an answer that includes the word "variant" or "new"; prompt on Transmissable Spongiforum Encephalopathy before it is mentioned)