A class of proteins that contain a baculovirus internal repeat, including XIAP and hIAP1 and 2, are responsible for inhibiting this process, and that protein is inhibited by Smac and Omi.
A class of proteins that contain a baculovirus internal repeat, including XIAP and hIAP1 and 2, are responsible for inhibiting this process, and that protein is inhibited by Smac and Omi. Protein 14-3-3controls this process, and is elevated in the cerebrospinal fluid in patients with CJD. Another series of proteins responsible for regulating this process contain some combination of domains BH1 through 4; the prototype of that family is Bcl-2. Methods of assaying for this process include watching for the exclusion of the dye tryphan blue or nick-end labelling via the TUNEL assay. This process occurs interdigitally during limb development, during selection of T-cells, and exactly 191 times during the development of C. elegans. For 10 points, name this process, known as programmed cell death.
A class of proteins that contain a baculovirus internal repeat, including XIAP and hIAP1 and 2, are responsible for inhibiting this process, and that protein is inhibited by Smac and Omi.
 apoptosis [accept programmed cell death before said]