Belonging to the family orthomyxoviridae, their virulence is inhibited by zanamivir and oseltamivir, and these infectious agents are identified by the Hx Ny nomenclature, such as the H5N1 that spread from birds.
An S31N mutation on the gene encoding their M2 proton pump makes these entities resistant to drugs such as rimantadine and amantadine. Certain proteins on their surfaces allow them to bind to sialic acid residues and facilitate their entry into host cells, those being their hemagglutinin domains. Belonging to the family orthomyxoviridae, their virulence is inhibited by zanamivir and oseltamivir, and these infectious agents are identified by the Hx Ny nomenclature, such as the H5N1 that spread from birds. For 10 points, identify these viruses responsible for pandemics such as the "Hong Kong," "Spanish", and recent "Swine" variants.
An S31N mutation on the gene encoding their M2 proton pump makes these entities resistant to drugs such as rimantadine and amantadine.
influenza viruses [or flu viruses; prompt on viruses]