" The orientation of one form of this process is determined by the "positive inside rule.
A key sequence involved in a "classical" form of this process was discovered in a chimeric gene composed of pyruvate kinase and SV40 large T-antigen. The heterodimeric enzyme MPP cleaves the central molecule in another form of this process, which is accomplished by the action of Hsp70 as a "Brownian ratchet." The orientation of one form of this process is determined by the "positive inside rule." Folding by BiP follows a (*) co-translational form of this process accomplished by the binding of SRP to its receptor to allow interaction with a complex of Sec proteins. One form of this process is mediated by the TOM and TIM complexes, while another relies on glycosylation with mannose 6-phosphate. Günter Blobel won the 1999 Nobel Prize for determining that this process is facilitated by Nterminal signal peptide tags. For 10 points, name this process of localizing proteins to a specific organelle.
A key sequence involved in a "classical" form of this process was discovered in a chimeric gene composed of pyruvate kinase and SV40 large T-antigen.
protein sorting [accept protein trafficking, targeting, importing, translocation, transfer; uptake, compartmentalization, distribution or reasonable descriptive equivalents; accept protein tagging before mentioned; accept protein localization before "localization"; accept answers referring to localization in any specific organelles; prompt on generic answers about "transport" or "docking" or equivalents; antiprompt on "endomembrane system"; prompt on "secretion" or "vesicular transport" or related answers]