" For 10 points, identify this laboratory rodent.
The splotch mutation in this organism affects Pax3, which is expressed in their cardiac neural crest cells. Genic selection in this organism promotes high frequencies of the t-allele, which affects deme extinction and is a prominent example of meiotic drive. When females of this organism possess mutated copies of fosB, they become negligent mothers. The link between leptin and obesity was found in a study of them. In the first experiment to demonstrate bacterial transformation, this organism was injected with pneumococcus by Frederick Griffiths. Capecchi, Smithies and Evans pioneered a technique in this organism in which embryonic stem cells inactivate a gene by homologous recombination. That technique is "knock out." For 10 points, identify this laboratory rodent.
The splotch mutation in this organism affects Pax3, which is expressed in their cardiac neural crest cells.
mice [or mouse; or Mus musculus domesticus; or Mus musculus musculus]