Christian Rene de Duve discovered this organelle after centrifuging liver cells and discovering an abnormally high amount of acid phosphatase.
When TFEB translocates to the nucleus, it results in a corresponding increase in the number of these organelles. A glycosphingolipid in this organelle, iGb3, is necessary for the production of natural killer cells. P-type lectins direct enzymes that have been tagged with mannose-6-phosphate to this organelle. Christian Rene de Duve discovered this organelle after centrifuging liver cells and discovering an abnormally high amount of acid phosphatase. Malfunction of this organelle can lead to a buildup of gangliosides in Tay-Sachs disease. For 10 points, name these organelles that perform autophagy by digesting unneeded or excess cellular materials.
When TFEB translocates to the nucleus, it results in a corresponding increase in the number of these organelles.
lysosomes