Abnormally high levels of them cause polycythemia, and they are destroyed and stored in the spleen.
The direct Coombs test detects antibodies on the surface of these entities. They are deformed in patients in whom a glutamic acid is replaced with a valine in a certain protein; the resulting disease confers immunity to (*) malaria. Abnormally high levels of them cause polycythemia, and they are destroyed and stored in the spleen. These cells are biconcave and have no nucleus, and their levels are lowered in patients with anemia. For 10 points, these are what hemoglobin-containing cells that transport oxygen to tissue, also called red blood cells.
The direct Coombs test detects antibodies on the surface of these entities.
{erythrocytes} [accept {red blood cells} before it is read]