Ones found in Tetra-hymena contain the sequence GGGTGG, while all vertebrates have repeats of TTAGGG, and in 1998, Bodnar et al demonstrated that these structures may be maintained indefinitely in certain cell lines without becoming cancerous or losing the typical 100 base pairs per mitosis typical for somatic cells.
These structures may dimerize, forming G-quartets, which may mediate the process of recombination. The TRAP assay is used to detect activity of their namesake enzyme, a form of reverse transcriptase. Ones found in Tetra-hymena contain the sequence GGGTGG, while all vertebrates have repeats of TTAGGG, and in 1998, Bodnar et al demonstrated that these structures may be maintained indefinitely in certain cell lines without becoming cancerous or losing the typical 100 base pairs per mitosis typical for somatic cells. Those found in Dolly the sheep are only 80% of their normal length, and it is thought that somatic cell clones age prematurely because of the diminished length of, FTP, what structures that prevent loss of the unreplicated 3' [three-prime] end of the lagging strand in chromosomal replication?
These structures may dimerize, forming G-quartets, which may mediate the process of recombination.
telomeres