A method to produce them entails fusing a cancerous B-cell with a spleen cell that has already developed a response to a given antigen.
Commercial examples of these include Vitaxin, which binds to vascular integrin to inhibit angiogenesis and one which binds to tumor necrosis factor-alpha, infliximab. Their usefulness is limited by the HAMA problem and the first step to creating them is finding myeloma cells that cannot synthesize HGPRT. A method to produce them entails fusing a cancerous B-cell with a spleen cell that has already developed a response to a given antigen. FTP, identify these immune-system molecules so named because they are all identical reproductions of the original cell and because they target only one antigen, the invention of which won Kohler and Milstein the 1984 Nobel Prize in Medicine.
Commercial examples of these include Vitaxin, which binds to vascular integrin to inhibit angiogenesis and one which binds to tumor necrosis factor-alpha, infliximab.
monoclonal antibodies (prompt on antibodies before "HAMA")