One modification to this reaction uses an organolithium reagent to convert the erthyro intermediate to the threo intermediate.
One modification to this reaction uses an organolithium reagent to convert the erthyro intermediate to the threo intermediate. Reactions which achieve the same goal as this reaction include the Peterson and Julia reactions, and using Tebbe's reagent yields a product that can also be produced in this reaction. This reaction proceeds via a four membered ring intermediate, which leads to the fact that this reaction only yields a Z product. In a lead up to this reaction, a strong base is applied to an alkyl halide and a triphenylphosphene to generate a ylide ("ill-id"), which in turn forms a betaine by attacking a carbonyl. For 10 points, identify this reaction which forms an alkene from a carbonyl and a phosphonium ylide, named for its German discoverer.
One modification to this reaction uses an organolithium reagent to convert the erthyro intermediate to the threo intermediate.
Wittig reaction