It was discovered in a sample of staphylococcus aureus, when its discoverer noted its ability to hinder bacterial growth.
A pathway in its production involves ketoglutaric acid with aminoadipate as an intermediate. Containing a central ring of three carbons and one nitrogen, its G variety contains a benzyl ring and its structure was determined by Dorothy Hodgkin. Margaret Rousseau would play a key role in the mass production of this, which was aided by a cantaloupe found in Peoria, Illinois. Since it works by preventing the formation of peptidoglycan in the cell wall, its effectiveness is directly related to the result of a Gram test on the sample. It was discovered in a sample of staphylococcus aureus, when its discoverer noted its ability to hinder bacterial growth. FTP, this antibiotic discovered in 1928 by Alexander Fleming.
A pathway in its production involves ketoglutaric acid with aminoadipate as an intermediate.
{Penicillin}