Cubilin is the receptor for the bound form of this protein, whose substrate is released by cathepsin L-mediated degradation and transported to tissue by the TCN2 protein.
Experiments by Nyberg et al. showed that members of the genus Diphyllobothrium are able to split the bound form of this protein. Cubilin is the receptor for the bound form of this protein, whose substrate is released by cathepsin L-mediated degradation and transported to tissue by the TCN2 protein. Type II antibodies that bind to a complex of this protein and its substrate block the uptake of that complex by brush border cells. This compound is sometimes called Castle's compound after William Castle, who hypothesized its existence when studying patients suffering from achlorhydria. This protein is the non- radioactive compound administered in the Schilling test. This protein binds to a molecule that is released from salivary haptocorrin by trypsin degradation, and it is secreted by the parietal cells of the stomach. For 10 points, name this protein that helps in the absorption of cyanocobalamin, aka vitamin B12, and whose deficiency is a cause of pernicious anemia.
Experiments by Nyberg et al. showed that members of the genus Diphyllobothrium are able to split the bound form of this protein.
intrinsic factor or compound [accept IF; accept Castle's intrinsic compound until mentioned]