That queen with this name earned the epithet "the Catholic" and sponsored the voyages of Christopher Columbus.
One queen with this name fought the Chincha Island war and was forced into exile in 1868 after becoming the only queen-regent of a unified Spain. Another queen of this name was nicknamed "The She-Wolf of France" and aided Roger Mortimer in overthrowing her husband Edward II. Another queen with this name expelled all Jews from her kingdom in the Alhambra decree and was the mother of Joanna the Mad. That queen with this name earned the epithet "the Catholic" and sponsored the voyages of Christopher Columbus. For 10 points, give this name held by a queen of Castille whose marriage to Ferdinand of Aragon unified Spain.
One queen with this name fought the Chincha Island war and was forced into exile in 1868 after becoming the only queen-regent of a unified Spain.
{Isabella}