This compound's production is dependent on TPH1 in the pineal gland and TPH2 in the Raphe nuclei.
One class of antagonists of this compound's receptor is used to treat the nausea associated with chemotherapy, and carcinoid syndrome occurs when tumors secrete this compound excessively. In the hepatic portal vein, platelets commonly sequester this compound. This compound's production is dependent on TPH1 in the pineal gland and TPH2 in the Raphe nuclei. LSD agonizes this compound's 2A receptor, and this compound is most abundantly produced in the enterochromaffin cells of the GI tract. It breaks down into 5-HIAA in the liver via monoamine oxidases, and this neurotransmitter's effects can be enhanced by Celexa and Zoloft, which block this compounds reuptake. Synthesized from tryptophan and also known as 5-HT, for 10 points, name this neurotransmitter whose levels are lowered in depression and anxiety disorders.
One class of antagonists of this compound's receptor is used to treat the nausea associated with chemotherapy, and carcinoid syndrome occurs when tumors secrete this compound excessively.
{Serotonin} or 5-HT or {5}-{Hydroxytryptamine}