For ten points, name this disease which probably afflicts the Pope and Muhammad Ali.
Characterized by nigrostriatal degeneration, the presence of the enzymes MAO-B and COMT worsen its effects.  Symptoms such as blepharospasm, or forced eyelid closure and bradykinesia, a difficulty in starting and stopping motions, are usually improved with dopamine-elevating drugs such as L-dopa.  For ten points, name this disease which probably afflicts the Pope and Muhammad Ali.
Characterized by nigrostriatal degeneration, the presence of the enzymes MAO-B and COMT worsen its effects.  
Parkinson's disease