As with antibodies, V(D)J recombination affects the development of these cells.
The activation of these cells involves interactions between the Zap-70 kinase and the ITAM regions of their CD3 receptors. One class of these cells carries out its function by releasing the enzyme perforin. These cells recognize peptide segments transported by MHC proteins. As with antibodies, V(D)J recombination affects the development of these cells. These cells are subjected to positive and negative selection during their development. These cells are classified into CD4 or CD8 types, and these cells develop in the thymus. For 10 points, name these leukocytes which come in 'helper' and 'cytotoxic' varieties.
The activation of these cells involves interactions between the Zap-70 kinase and the ITAM regions of their CD3 receptors.
T cells [or helper T cells; or cytotoxic T cells]