When this organ is sufficiently damaged, its functional tissue is replaced by fibers and scars in cirrhosis.
One disease where certain vessels in this organ are blocked due to inflammation is PSC. A value that can be used to help determine the cause of a disease of this organ compares the ratio between AST and ALT, and is sometimes named for De Ritis. Upon damage to this non pancreas organ, its namesake stellate cells activate and secrete scar tissue. This organ processes a compound made from the catabolism of (*) heme to make it water soluble, and that compound, bilirubin, causes the yellowness seen as a sign of many diseases of this organ, jaundice. When this organ is sufficiently damaged, its functional tissue is replaced by fibers and scars in cirrhosis. For 10 points, name this organ which is often damaged in alcoholics due to its function in detoxification.
One disease where certain vessels in this organ are blocked due to inflammation is PSC.
Liver