That same complex containing this molecule's receptor can also activate caspase 8, triggering apoptosis.
One of this molecule's receptors forms a complex with TAK1, TAB, and IRAK1. This molecule is in the same family as lymphotoxin-alpha. This molecule's active form is a homotrimer attached to either a p55 or p75 receptor. While it isn't Fas, this molecule's receptor forms a complex with TRADD, which causes IKK to phosphorylate I-kappa-B, causing the transport of (*) NF-kappa-B into the nucleus. That same complex containing this molecule's receptor can also activate caspase 8, triggering apoptosis. Inhibitors of this molecule include etanercept, adalimumab, and infliximab, which can be used to treat diseases such as psoriasis, Crohn's disease, and rheumatoid arthritis. For 10 points, name this cytokine involved in inflammation that was originally named for its ability to induce hemorrhagic cell death in mice tumors.
One of this molecule's receptors forms a complex with TAK1, TAB, and IRAK1.
Tumor Necrosis Factor alpha [or cachectin or cachexin, AFTER the word "etanercept" is read, do NOT prompt or accept on "tnf-beta," but accept it beforehand]