For 10 points, name this enzyme responsible for oxidizing alcohols to aldehydes and ketones, thereby serving a role in ethanol metabolism in those who drink the hooch and an oft cited cause of hangovers.
The cinnamyl-specific variety of this enzyme catalyzes the final step in the synthesis of lignin monomers. First isolated in yeast and later horse liver, this enzyme has an active site containing His-51 and Ser-48 residues that participate in key deprotonation steps. The active site is similar to carbonic anhydrase in that four cysteines form a tetrahedron around a zinc atom that coordinates to this enzyme's main substrate. It functions by transferring protons from that namesake substrate to NAD+ or NADP+ to generate an alkoxide, which then yields a carbonyl product. For 10 points, name this enzyme responsible for oxidizing alcohols to aldehydes and ketones, thereby serving a role in ethanol metabolism in those who drink the hooch and an oft cited cause of hangovers.
The cinnamyl-specific variety of this enzyme catalyzes the final step in the synthesis of lignin monomers.
{alcohol dehydrogenase} [prompt on “{ADH}”]