The Relish protein in drosophila is one member of this family.
The YopJ factor from Yersina pestis inhibits the protein responsible for inhibiting this factor in the cytosol, and some members of this family mature after degradation of their C-terminal ankyrin repeats. The Relish protein in drosophila is one member of this family. It is phosphorylated via the ZAP70-Protein Kinase C cascade, and the activation of Akt by Toll-like receptors has the same effect. Usually bound to Ik-beta-A in the cytoplasm, all proteins in this family are homologous to the Rel oncogene.  Initially discovered as an enhancer-binding protein in B cells, its phosphorylation allows it to be taking up by nuclear pores. For fifteen points, name this "master regulator," a transcription factor and oncogene responsible for cellular responses to stress, disease, and a million other things.
The YopJ factor from Yersina pestis inhibits the protein responsible for inhibiting this factor in the cytosol, and some members of this family mature after degradation of their C-terminal ankyrin repeats.
{Nuclear} factor {kappa} B