EP300 and MYST family proteins carry out this modification.
This activity is carried out by a protein complex that contains a BRPF scaffolding protein and two PHD domains. Protein complexes that carry out this process include the MOZ/MORF and HBO1 complexes, which both contain an ING protein. In Goetze et al.'s (X)PX ["X-P-X"] rule, the presence of proline at residues one or two of a nascent peptide prevents the occurrence of this modification. This modification is recognized by a conserved 110-residue module that consists of loops of alpha helices named ZA and BC, in which the BC-loop contributes an asparagine residue to stabilize one amino acid with this modification. EP300 and MYST family proteins carry out this modification. Bromodomains recognize this modification on lysine residues, which occurs more often in euchromatin than in heterochromatin. For 10 points, name this reaction, a post translational modification that involves the addition of a COCH3 ["C-O-C-H-3"] group, commonly done to histones by proteins called HATs
This activity is carried out by a protein complex that contains a BRPF scaffolding protein and two PHD domains.
acetylation [or ethanoylation; accept word forms acetylate or add acetyl groups; do not accept or prompt on "deacetylation" or "removing of an acetyl group"]