One regulator of this pathway is FOXO1 (read: "Fox-Oh-one"), which stimulates this process by increasing transcription of necessary enzymes.
One regulator of this pathway is FOXO1 (read: "Fox-Oh-one"), which stimulates this process by increasing transcription of necessary enzymes. Another positive regulator of this pathway causes the degredation of fructose 2,6 bisphosphate and inhibits a pathway that runs opposite to this one; that enzyme is PKA. The Cori cycle uses this pathway to generate glucose from a compound that is produced by the body during exercise.  Activation of this pathway causes increased transcription of PEPCK (read: "pep C K") and glycogen-6-phosphotase. Those enzymes are needed to reverse the reactions catalyzed by hexokinase and pyruvate kinase. For 10 points, name this process stimulated by glucagon that takes place in the mitochondria and cytosol of hepatocytes and uses substrates like lactate and glycerol to produce glucose.
One regulator of this pathway is FOXO1 (read: "Fox-Oh-one"), which stimulates this process by increasing transcription of necessary enzymes.
{Gluconeogenesis}