They form linear filaments from alpha and beta tubulin dimers, and are formed at the aster, though in animal cells they originate from a centrosome.
Charcot-Marie-Tooth disease is caused by a mutation in a gene coding for a molecule associated with these. The drug Taxol prevents their depolymerization, as does nonhydrolyzable GTP, but Colchicine, colcemid, and nocadazol inhibit their polymerization. Tau proteins form these molecules into bundles, and MAPs bind to them. Kinesins and Dyenins move toward the plus and minus end respectively of these structures, and they form a nine plus two pattern in flagella. They form linear filaments from alpha and beta tubulin dimers, and are formed at the aster, though in animal cells they originate from a centrosome. For 10 points, name these components of the cytoskeleton along with actin fibers and intermediate fibers, molecular fibers that form spindle fibers during mitosis.
Charcot-Marie-Tooth disease is caused by a mutation in a gene coding for a molecule associated with these.
{Microtubules} [accept {tubulin} until "{depolymerization}"]