Mutations in fibulin-5 and complement factor
Mutation of ABC R cause a rare juvenile form of this condition caused by lipofuschin buildup, known as
 Stargardt' disease. Mutations in fibulin-5 and complement factor H have been associated with this disease,
 which can be diagnosed using the Amsler Grid Test. Lucentis and Avastatin treat it by inhibiting VEGF,
 and this disease is caused by aberrant growth of blood vessels in the choroid. Drusen are another symptom
 of this disease, whose sufferers also experience scotomas, or floaters. It comes in wet and dry forms, and its
 hallmark symptom is breakdown of the namesake region of the retina. For 10 points, name this condition
 which causes loss of central vision, a leading cause of blindness.
Mutation of ABC R cause a rare juvenile form of this condition caused by lipofuschin buildup, known as
 Stargardt' disease.
{Macular degeneration}