It uses a pair of aspartate residues to perform its most important function, using a parallel evolution scheme similar to that seen in HIV protease.
It uses a pair of aspartate residues to perform its most important function, using a parallel evolution scheme similar to that seen in HIV protease. Created as an inactive "proenzyme," it initially has a block of 44 extra amino acids that cover the active site groove until it has reached its destination. The second enzyme to be crystallized, after urease, and the first to be synthesized, by Theodor Schwann in 1836, it is completely inactive above pH levels of 6, which explains the need for hydrochloric acid as a catalyst. FTP, name this enzyme of the stomach which degrades whole proteins into their peptide constituents.
It uses a pair of aspartate residues to perform its most important function, using a parallel evolution scheme similar to that seen in HIV protease.
pepsin