The inner membrane of this organelle is folded into cristae and the presence of a double membrane around it suggests it is the product of endosymbiosis.
Proteins tagged for transport to this organelle have a signal sequence on their N-terminus that tends to fold into an amphipathic alpha helix. Protein transport in this organelle is mediated by the TOM, TIM and OXA complexes. An unusual "double" phospholipid with four fatty acid chains, cardiolipin, is found primarily in it. Degeneration of retinal ganglion cells is linked to this organelle in Leber's hereditary optic neuropathy. Unusually, instead of being a stop codon, UGA codes for tryptophan in this organelle. Proteins covalently linked to a heme molecule are found in this organelle and are called cytochromes. The inner membrane of this organelle is folded into cristae and the presence of a double membrane around it suggests it is the product of endosymbiosis. For 10 points, name these organelles where cellular respiration and ATP synthesis occur.
Proteins tagged for transport to this organelle have a signal sequence on their N-terminus that tends to fold into an amphipathic alpha helix.
mitochondria [or mitochondrion]