The Drosophila X virus is thought to trigger this pathway as a means of innate immunity.
The Drosophila X virus is thought to trigger this pathway as a means of innate immunity. This pathway is responsible for guiding H3K9 methylation in the centromeric regions of S. Cerevisiae. Disruption of P-bodies leads to blunting of this pathway, which was elucidated by the discovery of the lin-4 gene. The Flavr Savr tomato takes advantage of this pathway, which relies on exportin-5 to transport the products of Drosha cleavage to the cytoplasm. Argonaute selects the guide strand to load into the RISC complex, which then can target complementary mRNAs for degredation in this pathway. Craig Mello and Andrew Fire won the Nobel Prize for elucidating this pathway. For 10 points, name this mechanism which uses anti-sense RNA to silence a gene.
The Drosophila X virus is thought to trigger this pathway as a means of innate immunity.
RNA interference [accept innate immunity before mention]