For 10 points, name these cells responsible for nursing sperm during their development, named for an Italian.
The SF-4 and MSC-1 cell lines were created for these cells, though the most established culture model for them is the TM4 line. During differentiation, these cells express Desert Hedgehog, and these cells are absent in germ cell aplasia, also known as Del Castillo syndrome. These cells express the ERM transcription factor and a particular globulin, that is a glycosylated version of SHBG. In addition to expressing ABP, Sox9 is specifically expressed in these cells during development. During development these cells secrete a TGF-beta family member responsible for promoting the formation of the Wolffian duct, known as anti-Mullerian hormone ?. Their formation is SRY-dependent, and these cells secrete inhibin and activin, which is responsible for modulating their responses to FSH. These cells exist in the seminiferous tubules, where they tight junction to each other to form the blood-testes barrier. For 10 points, name these cells responsible for nursing sperm during their development, named for an Italian.
The SF-4 and MSC-1 cell lines were created for these cells, though the most established culture model for them is the TM4 line.
{Sertoli} cells