It was initially defined as being impossible whenever interdependent organs are sufficiently in contact and sufficiently extensive.  
It was connected by Louis Wirth to urbanism, who used it to refer to life in big cities.  It was initially defined as being impossible whenever interdependent organs are sufficiently in contact and sufficiently extensive.  Its more recent usage is associated with Robert K. Merton, who suggested that it is prevalent in individuals who clearly know what is expected of them from society but are consistently unable to meet the standard.  First popularized in The Division of Labor in Society, FTP, name this condition theorised by ?ile Durkheim now associated with a lack of regulation and break down of norms.
It was connected by Louis Wirth to urbanism, who used it to refer to life in big cities.  
anomie