Cationic complexes may be used for this reaction in order to favor the more electropositive site despite steric hindrance.
A versatile, mild method to access pterocarpans was achieved by the Evangelista group using a variant of this reaction in which an extra step sees a nucleophilic replacement by hydroxyl, which results in tetrahydrofuran derivatives. Cationic complexes may be used for this reaction in order to favor the more electropositive site despite steric hindrance. Oxidative variations on this reaction are named for Fujiwara and Moritani. This reaction can be carried out without phosphine ligands in ionic liquids like BMIM-PF6. Often compared mechanistically to the Wacker process, this reaction, unless silver salts are used, can result in the migration of double bonds due to the kinetics of beta-hydride elimination and requires stoichiometric amounts of a strong base for the final reductive elimination step. For 10 points, name this organometallic reaction, the palladium-catalyzed coupling of a halide or pseudohalide to an alkene.
A versatile, mild method to access pterocarpans was achieved by the Evangelista group using a variant of this reaction in which an extra step sees a nucleophilic replacement by hydroxyl, which results in tetrahydrofuran derivatives.
{Mizoroki}-{Heck} reaction