Impaired function of this structure causes the abnormal growth poky strain of the Neurospora mold and the petite mutation in Saccharomyces results in its mutation.  
Impaired function of this structure causes the abnormal growth poky strain of the Neurospora mold and the petite mutation in Saccharomyces results in its mutation.  MERRF disease also causes aberrant ones and Leber's hereditary optical neuropathy sufferers exhibit lesions within its genome. It contains a large channel-protein called porin, which is found outside of the large internal space known as the matrix.  For 10 points - name this structure that also contains a series of infoldings known as cristae, and which is often called the "powerhouse of the cell."
Impaired function of this structure causes the abnormal growth poky strain of the Neurospora mold and the petite mutation in Saccharomyces results in its mutation.  
mitochondria or mitochondrion