Rare mosaic and translocation varieties of it exist, though this disease is usually caused by nondisjunction in meiotic gamete production.
People with this condition may display small light-colored dots on the iris, known as Brushfield spots. Heart defects and poor muscle tone are apparent in infants, and most adults with this disorder display symptoms of Alzheimer's disease by age 50. Rare mosaic and translocation varieties of it exist, though this disease is usually caused by nondisjunction in meiotic gamete production. Epicanthic folds and a single transverse crease on the palm are common, and it can be detected by karyotyping. This disease can cause hearing loss and is more likely with increased maternal age. For 10 points, name this chromosomal disorder often resulting in developmental delays, also known as trisomy 21.
People with this condition may display small light-colored dots on the iris, known as Brushfield spots.
{Down's} syndrome [accept {trisomy 21} before it's mentioned]