New therapies may be inspired by a recent proteomic analysis of the flagellum of the responsible agent, a kinetoplastid parasite.  
Haptoglobin-related protein in a certain HDL is thought to account for the natural resistance of humans to a pathogen similar to the one responsible for this disease.  New therapies may be inspired by a recent proteomic analysis of the flagellum of the responsible agent, a kinetoplastid parasite.  The pathogen promotes its own growth by triggering secretion of interferon-gamma and produces multiple waves of fever by generating clones covered by different variable surface glycoproteins.  After breaking down the host's defenses, the parasites cross the blood-brain barrier, producing slurred speech and mobility issues.  FTP, name this disease caused by trypanosomes and carried by the tsetse fly associated with odd slumber habits.
Haptoglobin-related protein in a certain HDL is thought to account for the natural resistance of humans to a pathogen similar to the one responsible for this disease.  
African Sleeping Sickness (accept trypanosomiasis before mention of trypanosome)