A drug-induced type of it can occur after long-term use of isoniazid or quinidine.
In addition to Aicardi-Gouti?es syndrome, a mutation in the TREX1 gene is associated with this disease. A drug-induced type of it can occur after long-term use of isoniazid or quinidine. A number of genes on chromosome 1 have been linked to it, including those for Fc? receptors and interleukin 10. High levels of antiphospholipid antibodies found in sufferers of this disease may accelerate atherosclerosis, and this disease may also cause Libman-Sacks endocarditis. Sufferers of this disease, prevalent in nine times as many women as men, demonstrate high levels of circulating apoptotic cells, and its most recognizable symptom is a photosensitive butterfly-shaped rash. For 10 points, name this "great imitator," a chronic autoimmune disease in which that facial rash resembles the fur on the face of a wolf.
In addition to Aicardi-Gouti?es syndrome, a mutation in the TREX1 gene is associated with this disease.
systemic lupus erythematosus [or SLE]