A methylated form of this compound cannot be processed in Type 2 Arakawa's syndrome, and deficiencies of it lead to a block in demethylation of 5-methyl-THF according to the methyl trap hypothesis.
A methylated form of this compound cannot be processed in Type 2 Arakawa's syndrome, and deficiencies of it lead to a block in demethylation of 5-methyl-THF according to the methyl trap hypothesis. It is used as a cofactor by the enzyme that transforms homocysteine to methionine, known as MTR, and its also used as a co-factor in the creation of succinyl-CoA by methyl-malonyl-CoA mutase. Defects in its uptake can be treated using folic acid, which is able to stave off the symptoms of megaloblastosis. Its physiologically present as adenosylcobalamin and methyl cobalamin, and its uptake in the intestine relies on its binding to the glycoprotein haptocorrin, followed by binding to intrinsic factor. For 10 points, name this vitamin that has a corrin ring surrounding a cobalt atom.
A methylated form of this compound cannot be processed in Type 2 Arakawa's syndrome, and deficiencies of it lead to a block in demethylation of 5-methyl-THF according to the methyl trap hypothesis.
Vitamin {B12} or Cobalamin