A common cause of this disease is the malfunction of a diacidic sorting signal due to the deletion of phenylalanine residue 508 in a critical protein.
A common cause of this disease is the malfunction of a diacidic sorting signal due to the deletion of phenylalanine residue 508 in a critical protein. This disease often results in over-expression of the ENaC channel protein, due to a defect in an ABC-class transporter for thiocyanate and other anions. The structure that normally connects the epididymis to the urethra, the vas deferens, is often absent in males who suffer from this disease. This autosomal recessive disorder is often diagnosed with a sweat test, measuring the concentration of chloride in the fluid. For 10 points, name this disease which causes the buildup of thick mucus in the lungs.
A common cause of this disease is the malfunction of a diacidic sorting signal due to the deletion of phenylalanine residue 508 in a critical protein.
cystic fibrosis [or CF]