For 10 points, name this neurodegenerative disease that causes over half of elderly dementia cases.
Individuals with this disease exhibit a loss of locus coeruleus cells. The E allele of the apo-lipo-protein E4 gene increases the risk of this disease, which often results in a low level of acetylcholine in the brain. One hypothesized cause of this disease is hyper-phosphorylated tau proteins, which form neurofibrillary tangles. Another possible cause of this disease is the buildup of amyloid beta protein plaques. For 10 points, name this neurodegenerative disease that causes over half of elderly dementia cases.
Individuals with this disease exhibit a loss of locus coeruleus cells.
Alzheimer's disease