This interaction helps stabilize the secondary fold in protein folding and is responsible for the alpha helix.
Organocatalysts that exploit this interaction include the (thio)urea ones. The 6-12 Lennard-Jones potential is replaced with a 10-12 potential when modeling this interaction. A signature of this interaction is a redshift in IR spectra, which corresponds to bond lengthening. It was first elucidated in its most common setting by Latimer and Rodebush. This interaction helps stabilize the secondary fold in protein folding and is responsible for the alpha helix. Protic solvents are defined as being able to participate in it. This interaction results from lone pairs of electrons on electronegative atoms bonded to a namesake element. For 10 points, identify this relatively strong intermolecular interaction that explains the high boiling point of water.
Organocatalysts that exploit this interaction include the (thio)urea ones.
hydrogen bonds [or H-bonds; or word forms]