This vitamin is lacking in pernicious anemia.
This compound's total synthesis involves the cyclization of methionine to create alpha-corrnorsterone, which contains this compound's D-ring. Katzung showed that the step that employs this compound to activate methionine synthase is the rate-limiting step of methionine synthesis. This compound is a cofactor in the conversion by methylmalonyl coenzyme A mutase of methylmalonic acid to succinate. This compound can reverse dexamethasone-induced cleft palate in rodent embryos. Its synthesis was made more intimidating by its nine chiral centers, six of which are consecutive; that synthesis was achieved by Woodward and Eschenmoser. Vitamers of this vitamin include one that includes an adenosyl ligand, which is sometimes called dibencozide. This vitamin is lacking in pernicious anemia. This vitamin's forms all possess a cobalt center chelated by a porphyrin-like system with three L-type bonds and one X-type bond. For 10 points, name this vitamin whose most air-stable form is cyanocobalamin, a B vitamin intimately involved in metabolism.
This compound's total synthesis involves the cyclization of methionine to create alpha-corrnorsterone, which contains this compound's D-ring.
vitamin B12 [prompt on {cobalamins} before mention; accept {methylcobalamin} before mention; accept {cyanocobalamin} before mention]