Though he had a son with Princess Maria who became Don Carlos of Spain, his most ambitious marriage was childless, and announcement of it sparked Thomas Wyatt's rebellion in his wife's country.
He married Elizabeth of Valois as a consequence of the Peace of Cateau-Cambr?is. Later, he sent his half brother Don John of Austria to win the Battle of Lepanto after losing the succession of the Holy Roman Empire to Ferdinand I. Though he had a son with Princess Maria who became Don Carlos of Spain, his most ambitious marriage was childless, and announcement of it sparked Thomas Wyatt's rebellion in his wife's country. FTP, name this son of Charles I of Spain, whose marriage to Mary Tudor proved as fruitless to his ambitions on England as his later effort, the Spanish Armada.
He married Elizabeth of Valois as a consequence of the Peace of Cateau-Cambr?is.
Philip II [prompt on Philip]