A 1992 study by Korenberg demonstrates that these agents are useful as probes for chromosome painting, as well as for ordering probes along chromosomes using FISH methods.
A 1992 study by Korenberg demonstrates that these agents are useful as probes for chromosome painting, as well as for ordering probes along chromosomes using FISH methods. These creations are capable of being replicated and selected for in an Enterobacteriacae strain which has maltose permease, the E. coli malB gene product. The early examples of them, such as the series created by DiLella and Woo in 1987, were typically 5kb in size. First developed by John (*) Collins and Barbara Hohn in 1978, their characteristic feature is they are able to use the lambda delivery system for efficient cloning of large passenger DNAs. Often used in constructing genomic libraries, these vectors are named for their lambda sites which allow DNA to be packaged into phage particles. FTP, name these cloning vectors which are similar to plasmids, except that they contain a cohesive end site.
A 1992 study by Korenberg demonstrates that these agents are useful as probes for chromosome painting, as well as for ordering probes along chromosomes using FISH methods.
cosmids