Most of the proteins in this pathway are serine proteases that cleave each other, one of which is bound to von Willebrand factor.
One protein in this pathway has a G20210A mutant. This pathway is aberrantly activated by anti-phospholipid antibodies, while one pathway to initiate it relies on high-molecular weight kininogen. The aPTT and PT tests can be used to determine if particular proteins in this pathway are defective; said proteins include Hageman factor and another whose mutation causes Christmas disease. Most of the proteins in this pathway are serine proteases that cleave each other, one of which is bound to von Willebrand factor. For 10 points, name this cascade that includes Factors V, VIII, IX, X, etc, responsible for stopping the flow of blood at wounds.
One protein in this pathway has a G20210A mutant. This pathway is aberrantly activated by anti-phospholipid antibodies, while one pathway to initiate it relies on high-molecular weight kininogen.
blood coagulation cascade [or blood clotting cascade; accept reasonable equivalents]