Red blood cells are broken down in this organ by macrophages called Kupffer cells, and this organ receives blood through the portal vein system.
Along with the heart, this organ is severely damaged in Alagille syndrome, which results from the deletion of a gene coding for the JAG1 protein. The Child-Pugh scale is used to evaluate damage to this organ, which can also occur when veins leading to it are occluded in Budd-Chiari syndrome. Morrison's pouch lies behind this this organ, which is suspended by the coronary ligament. It is one of the major sites of damage as a result of copper accumulation in Wilson's disease, and it is attached to the diaphragm and anterior abdominal wall by the falciform ligament. Red blood cells are broken down in this organ by macrophages called Kupffer cells, and this organ receives blood through the portal vein system. For 10 points, identify this site of gluconeogenesis, a four-lobed, bile-secreting organ.
Along with the heart, this organ is severely damaged in Alagille syndrome, which results from the deletion of a gene coding for the JAG1 protein.
{Liver}