For 10 points, name these sequences located at the tips of chromosomes.
Inability to regulate these structures is the cause of dyskeratosis congenita. These structures are often studied using Flow-FISH, and iPSCs achieve one of their hallmark characteristics due to the consistent presence of these structures. The enzyme complexes that give rise to these structures uniquely do not require extrinsic primers for (*) DNA synthesis; those enzymes are a class of reverse transcriptases. Repeated cell division causes the shrinking of these structures, which causes cells to approach their Hayflick limit. Cancer cells can achieve replicative immortality by replicating theses structures, which in humans are tandem repeats of the sequence TTAGGG. For 10 points, name these sequences located at the tips of chromosomes.
Inability to regulate these structures is the cause of dyskeratosis congenita.
telomeres