CED-3, which performs their function in C. elegans, is a homolog of ICE, or number 1 of these enzymes.
The Omi/HtrA2 and DIABLO families of proteins binds to enzymes that inhibit these proteins, one of which processes the transcription factor SATB1 in activated T cells. Abnormally high concentrations of one of them are found in polycystic kidney disease, and two others cleave the huntingtprotein in Huntington's disease. Granzyme B activates multiple proteins in this family. One of them is recruited by FADD, and another by a cytochrome c/Apaf-1 complex. Numbers 8 and 9 are the "initiators" of their namesake cascade, which occurs at the death-induced signaling complex. CED-3, which performs their function in C. elegans, is a homolog of ICE, or number 1 of these enzymes. For 10 points, name these proteases that play a critical role in apoptosis.
The Omi/HtrA2 and DIABLO families of proteins binds to enzymes that inhibit these proteins, one of which processes the transcription factor SATB1 in activated T cells.
caspases [or cysteine-dependent aspartases]