n-Octanoylation of its Serine-3 residue by GOAT protein is necessary for its activity, while high serum levels of this hormone were shown to contribute to (*) hyperphagia in Prader-Willi Syndrome.
When administered to rats, this hormone both induces growth hormone secretion and upregulates the expression of Fos and EGR-1 in the arcuate nucleus. In one pathway, this compound stimulates AMP-activated protein kinase and Akt leading to increased eNOS expression. n-Octanoylation of its Serine-3 residue by GOAT protein is necessary for its activity, while high serum levels of this hormone were shown to contribute to (*) hyperphagia in Prader-Willi Syndrome. Produced by the P/D1 cells of the fundus and coded for by the GHRL gene, this hormone antagonizes another hormone that is produced in adipose tissue and inhibits neuropeptide Y and agouti-related protein. Secreted by the epsilon cells of the Islets of Langerhans, for 10 points, name this 28 amino acid appetite-stimulating hormone that works in opposition to leptin.
When administered to rats, this hormone both induces growth hormone secretion and upregulates the expression of Fos and EGR-1 in the arcuate nucleus.
ghrelin