Krukenberg's disease is an example of this phenomenon, and it may be studied with microcell-mediated chromosomal transfer.  
The murine gene nm23 is a prototype for suppressors of this process.  Krukenberg's disease is an example of this phenomenon, and it may be studied with microcell-mediated chromosomal transfer.  Stromelysin and other matrix metalloproteases promote this process by destroying collagen and other components of the extracellular matrix, allowing cells to proceed through steps like intravasation and extravasation that permit their travel through the bloodstream.  FTP, identify this process by which cancerous cells migrate from a primary tumor to other sites in the body.
The murine gene nm23 is a prototype for suppressors of this process.  
metastasis