This disease causes depletion of CREB binding protein, and the main protein involved in this disease interacts with HIP1, a clathrin-binding protein.
The main diagnostic symptom of this disease also characterizes a disorder that is one of the Jones criteria and is associated with streptococci infections, called Sydenham disorder. This disease causes depletion of CREB binding protein, and the main protein involved in this disease interacts with HIP1, a clathrin-binding protein. It chiefly occurs due to the presence of an excess of 36 contiguous glutamine residues in a polyQ sequence near the amino terminus of said protein. The mutation of a namesake gene on chromosome 4 results in, for 10 points, what autosomal dominant disease that causes involuntary muscle movements and progressive cognitive degeneration due to the aggregation of a misfolded protein in the central nervous system.
The main diagnostic symptom of this disease also characterizes a disorder that is one of the Jones criteria and is associated with streptococci infections, called Sydenham disorder.
Huntington's chorea [prompt on "chorea"]