Hydrolysis of Ran-GTP to Ran-GDP and dissociation of Ran-GDP with the help of Ran-GEF helps these structures perform their characteristic activity; that activity is performed with the aid of karyopherins called importins and exportins.
The "reduction of dimensionality" model attempts to explain the selectivity of these structures. The assembly of these structures was first studied with the use of the chelator BAPTA and lectin WGA, and one model for their function involves the binding of the successive FG residues that line these complexes. These structures contain a molecule called the "center plug" and one end of these structures have a basket like shape. Hydrolysis of Ran-GTP to Ran-GDP and dissociation of Ran-GDP with the help of Ran-GEF helps these structures perform their characteristic activity; that activity is performed with the aid of karyopherins called importins and exportins. For 10 points, identify these structures which are embedded in the envelope of a namesake organelle and which facilitate the transport of molecules between that DNA containing organelle and the cytosol.
The "reduction of dimensionality" model attempts to explain the selectivity of these structures.
{nuclear pores} [or {nuclear pore} complexes; prompt on {Nups} or {nucleoporins}]