Also the site of the Comnenian dynasty, For ten points, name this city located on the Bosporus, which was later called Constantinople and Istanbul.
Theodotus the Currier, who was excommunicated by the Roman Catholic Church for being an antitrinitarian, was a native of this place, and its first known bishop was Metrophanes. This city held out for two years against the forces of Phillip of Macedon, but would later be razed by Septimius Severus after a three year siege. Originally called Lygos, it was colonized by Megara in 658 BC and was named after the leader of that expedition. This city had supported the loser of the Battle of Chrysopolis, Licinius, though it would later be renamed by that battle's victor, who had gained control of the Western Roman Empire at the earlier Battle of Milvian Bridge. Also the site of the Comnenian dynasty, For ten points, name this city located on the Bosporus, which was later called Constantinople and Istanbul.
Theodotus the Currier, who was excommunicated by the Roman Catholic Church for being an antitrinitarian, was a native of this place, and its first known bishop was Metrophanes.
Byzantium (prompt on Constantinople or Istanbul till mentioned)