When reacted with a nitrile, they produce an imine anion that can be hydrolyzed into a ketone, and they can cause nucleophilic ring opening of epoxides.
When reacted with a nitrile, they produce an imine anion that can be hydrolyzed into a ketone, and they can cause nucleophilic ring opening of epoxides. Pouring a solution of them over dry ice followed by protonation results in carboxylic acids, which will not form addition products with these. One of their most common uses is reacting with aldehydes and ketones to form secondary and tertiary alcohols, respectively. Because they essentially act as carbanions, they can be protonated by weak acids to yield alkanes. FTP name these organometallic reagents that are formed by reacting an alkyl halide with magnesium, named for their French discoverer.
When reacted with a nitrile, they produce an imine anion that can be hydrolyzed into a ketone, and they can cause nucleophilic ring opening of epoxides.
Grignard reagents