Tcf3 and beta-catenin buffer the concentration of Nanog, which sequesters a transcription factor called Oct4 in these cells.
In these cells, Lin28 prevents the cleavage of an miRNA called let-7, and methylation of DNA by Dnmt1 is repressed in the nucleus. Tcf3 and beta-catenin buffer the concentration of Nanog, which sequesters a transcription factor called Oct4 in these cells. The ecological term "niche" is sometimes applied to these cells. They are injected into a blastocyst of a psuedopregnant mouse in the first step of a gene knockout. Yamanaka pioneered the study of the induced pluripotent type of these cells, which can form the endoderm, ectoderm, or mesoderm. For 10 points, name these cells that have not yet differentiated into specialized cells, and which can be be extracted from embryos.
In these cells, Lin28 prevents the cleavage of an miRNA called let-7, and methylation of DNA by Dnmt1 is repressed in the nucleus.
stem cells [or embryonic stem cells; or ES cells; or adult stem cells; or induced pluripotent stem cells; or iPS cells]