Commonly applied to find the isoelectric point of a protein or of a buffer solution, FTP, identify this equation, which gives the degree to which a compound will deprotonate given its pKa and the ambient pH.
It is replaced under certain conditions by a function calculated by combining the chemical activity with the dissociation of another compound, originally anilines substituted with electron-withdrawing groups. While the Hammett function is only applicable in extreme conditions, this equation also neglects the disproportionation of water, being just the logarithm of the expression for the equilibrium constant. Commonly applied to find the isoelectric point of a protein or of a buffer solution, FTP, identify this equation, which gives the degree to which a compound will deprotonate given its pKa and the ambient pH.
It is replaced under certain conditions by a function calculated by combining the chemical activity with the dissociation of another compound, originally anilines substituted with electron-withdrawing groups.
{Henderson}-{Hasselbalch} equation