The anti-EMR1 monoclonal antibody binds specifically to these cells, and they also express CD68 and CD14.
The anti-EMR1 monoclonal antibody binds specifically to these cells, and they also express CD68 and CD14. So-called "Heart Failure Cells" are created when these cells become laden with hemosiderin, and in atherosclerotic [ah-thuh-ROH-skleh-RAW-tik] plaques they become foam cells. One variant of these cells line the walls of liver sinusoids and are called Kupffer cells, and these cells' main function is triggered by activation of toll-like receptors, followed by actin polymerization. These cells differentiate from monocytes. They express MHC class II, which with they present antigens to helper T cells. For 10 points, name these immune cells which phagocytize [FAG-uh-seye-tize] debris and pathogens, whose name is Greek for "big eaters".
The anti-EMR1 monoclonal antibody binds specifically to these cells, and they also express CD68 and CD14.
{macrophages}