The synthesis of this neurotransmitter occurs in a single step and is catalyzed by ChAT.
An important source of studies of this neurotransmitter is the electroplax of Torpedo californica. Work by Fatt and Katz revealed that discrete quanta of this molecule result in miniature end plate potentials. The proteins agrin and rapsyn are involved in clustering receptors for it during creation of one type of synapse. High levels of this molecule are found in the basal nucleus of Meynert. In both the sympathetic and parasympathetic divisions, it is the neurotransmitter for preganglionic fibers. Unusually, its action is terminated by direct enzymatic hydrolysis by a namesake esterase. Myasthenia gravis is caused by antibodies blocking its nicotinic receptors, which are paired with muscarinic receptors. The synthesis of this neurotransmitter occurs in a single step and is catalyzed by ChAT. For 10 points, identify this first substance shown to be a neurotransmitter, which is found at the neuromuscular junction.
An important source of studies of this neurotransmitter is the electroplax of Torpedo californica.
acetylcholine [or Ach]