These can also by synthesized by a reaction that uses a base to absorb the acidic proton on the nitrogen atom in an intermediate, after the addition of the carbonyl group of a acid chloride to an amine, the Schotten-Baumann reaction.
One multi-component reaction to create them combines a ketone or aldehyde, a carboxylic acid, and an isocyanide in a reaction named for Passerini. Oximes can be converted to them by heating with sulfuric acid or phosphorus pentachloride in the Beckmann rearrangement, and these can be converted into carbamic acid via attempted halogenation of primary versions of these by the Hofmann rearrangement. These can also by synthesized by a reaction that uses a base to absorb the acidic proton on the nitrogen atom in an intermediate, after the addition of the carbonyl group of a acid chloride to an amine, the Schotten-Baumann reaction. For 10 points, name this class of molecules that contains an acyl group bound to a nitrogen atom.
One multi-component reaction to create them combines a ketone or aldehyde, a carboxylic acid, and an isocyanide in a reaction named for Passerini.
{amides}