A member of the alpha ketoglutarate family, it is derived from glutamate via a series of reactions including an oxidation, reduction, followed by an NADPH dependent reduction of the pyrroline double bond.
It is highly unlikely that one would find this amino acid in either an alpha helix or beta sheet; rather it is most often found in a beta turn. A member of the alpha ketoglutarate family, it is derived from glutamate via a series of reactions including an oxidation, reduction, followed by an NADPH dependent reduction of the pyrroline double bond. It, along with its 4-hydroxy version, composes some 30% of collagen. FTP name this amino acid who has the fourth smallest molecular weight and is unique because it is the only one whose R group is bonded to the amino group.
It is highly unlikely that one would find this amino acid in either an alpha helix or beta sheet; rather it is most often found in a beta turn.
proline