Found mostly in Ashkenazi Jews, FTP, identify this disease named after its British and American discoverers.
First diagnosed when describing a patient with a cherry-red spot on the retina, this disease affects the production of the lysosomal enzyme hexosaminidase A.  The result of this defect on chromosome 15 is the accumulation of the lipid ganglioside GM2 in the brain, resulting in neural degeneracy and death before the age of five.  Found mostly in Ashkenazi Jews, FTP, identify this disease named after its British and American discoverers.
First diagnosed when describing a patient with a cherry-red spot on the retina, this disease affects the production of the lysosomal enzyme hexosaminidase A.  
Tay-Sachs disease