Besides Dubin-Johnson, Gilbert, and
 Rotor's syndrome, inactivating mutations in UDP glucoronosyltransferase lead to accumulation of the
 unconjugated form of this substance in Crigler-Najjar syndrome.
One disorder that causes increased levels of this compound results from a mutation in the cMOAT gene,
 while another is caused by mutations leading to decreased UGT1. Besides Dubin-Johnson, Gilbert, and
 Rotor's syndrome, inactivating mutations in UDP glucoronosyltransferase lead to accumulation of the
 unconjugated form of this substance in Crigler-Najjar syndrome. Lab tests usually measure both the direct
 and indirect versions of this open-chain polypyrrole. Exposing this substance to light transforms it from the
 ZZ to EE isomer, which is why ultraviolet light is a treatment for the accumulation of this substance in
 newborns. For 10 points, name this product of heme metabolism, which when elevated causes jaundice.
One disorder that causes increased levels of this compound results from a mutation in the cMOAT gene,
 while another is caused by mutations leading to decreased UGT1.
{bilirubin} [or {conjugated} , unconjugated, direct or indirect {bilirubin} ]