Lipid rafts mostly contain sphingolipids and this compound.
During synthesis of Sonic hedgehog, this compound is added post-translationally to the N-terminus. ABCA1 transports this compound out of cells and is defective in Tangier disease. At high cellular levels of this compound, SCAP binds to SREBPs, transcription factors that activate its synthesis. Receptor-mediated endocytosis of this compound requires ApoB to bind its receptor. Lipid rafts mostly contain sphingolipids and this compound. The rate-limiting step of its biosynthesis is the reduction of HMG-CoA to mevalonate. That step can be inhibited by statins like Lipitor. Bile acids and vitamin D are formed from this compound. For 10 points, name this compound which normally maintains the fluidity of the cell membrane, but clogs arteries in atherosclerosis.
During synthesis of Sonic hedgehog, this compound is added post-translationally to the N-terminus.
cholesterol [or LDL or HDL or high-density lipoprotein or low-density lipoprotein before mention]