First discovered in 1984 in Tetrahymena by Greider and Blackburn, for 10 points, name this enzyme that works to elongate its namesake structures found at the ends of chromosomes.
Chromosomal mutations that cause the absence of one of this enzyme's subunits is associated with Cri du Chat. Geron's GRN163L attempts to stop cancer cell proliferation by binding directly to this enzyme's RNA template, therefore inhibiting it. Composed of TERT, TERC, and DKC1, this enzyme adds TTAGGG repeats to the 3' tail of DNA. Cells without this reverse transcriptase eventually reach their Hayflick limit. First discovered in 1984 in Tetrahymena by Greider and Blackburn, for 10 points, name this enzyme that works to elongate its namesake structures found at the ends of chromosomes.
Chromosomal mutations that cause the absence of one of this enzyme's subunits is associated with Cri du Chat.
telomerase