For 10 points, name this process by which by which the blood congeals after injury, which is impaired in hemophilia (HEE-mo-FILL-ee-uh).
This process can be reversed in a pathway involving urokinase ("YOUR"-oh-KINE-ase), and it is downregulated by prostacyclin (PROS-tuh-"SIGH"-klin). Christmas disease results from a lack of Factor IX involved in this process. During this process, the serine protease (PRO-tee-ase) thrombin (THROM-bin) converts fibrinogen (fie-BRIN-oh-jen) into fibrin (FIE-brin), which forms a mesh polymer. Platelets have several important roles in this process. For 10 points, name this process by which by which the blood congeals after injury, which is impaired in hemophilia (HEE-mo-FILL-ee-uh).
This process can be reversed in a pathway involving urokinase ("YOUR"-oh-KINE-ase), and it is downregulated by prostacyclin (PROS-tuh-"SIGH
{coagulation} [or {clotting}]