Schwarz, Tomari, and Zamori demonstrated that the primary enzyme in the final stage of this process was not Tudor-SN and suggested that magnesium was a cofactor.
Schwarz, Tomari, and Zamori demonstrated that the primary enzyme in the final stage of this process was not Tudor-SN and suggested that magnesium was a cofactor. This process may be prevented by an editing operation that forms inosine. Kulkami In one organism, this method was used in a 1998 study to interfere with GFP and produce "lumpy-dumpy larvae" as well as "strong twitchers." One phase of this process sees the binding of the guide strand in the RISC to argonaute; earlier, those twenty-to-twenty-five base pair long sequences were cleaved from longer sequences by Dicer. First discovered in C. elegans by Fire and Mello, for 10 points, name this process of gene silencing that uses siRNAs.
Schwarz, Tomari, and Zamori demonstrated that the primary enzyme in the final stage of this process was not Tudor-SN and suggested that magnesium was a cofactor.
RNA interference [or RNAi; or post-transcriptional gene silencing]