This advocate of a type of chemistry involving rapid synthesis of easy-to-make molecules, "click chemistry," used a cinchona ligand and an osmium-based catalyst to form vicinal diols from alkenes.
Among this man's early work was a study of an enzyme in the pathway used to convert squalene to cholesterol, and he developed a synthesis of (1,5) dienes using reductive coupling of allylic alcohols. He later used those allylic alcohols and a namesake titanium tartrate catalyst in a reaction co-discovered with Tsutomu Katsuki. This advocate of a type of chemistry involving rapid synthesis of easy-to-make molecules, "click chemistry," used a cinchona ligand and an osmium-based catalyst to form vicinal diols from alkenes. Along with William Knowles and Ryoji Nonori, this man received the 2001 Nobel Prize in Chemistry for his work on chirally catalyzed oxidation reactions. For 10 points, name this chemist now at The Scripps Research Institute, who has namesake asymmetric dihydroxylation and epoxidation reactions.
Among this man's early work was a study of an enzyme in the pathway used to convert squalene to cholesterol, and he developed a synthesis of (1,5) dienes using reductive coupling of allylic alcohols.
K(arl) Barry Sharpless