Regions with very high K sub s values are too saturated to allow the accurate use of this technique, which produces data that can be analyzed by (*) BEAST and classically employs cytochrome c or hemoglobin.
In 2010, Sperling et al used microRNA screens and this technique to discover the "spicule gap" in demosponges. When applied to plants, this technique is often "relaxed." Martin and Palumbi argued that this technique generates heterogeneous data because of the relatively rapid production of reactive oxygen species in homeotherms. Regions with very high K sub s values are too saturated to allow the accurate use of this technique, which produces data that can be analyzed by (*) BEAST and classically employs cytochrome c or hemoglobin. This "sloppy" technique relies on the same assumptions as UPGMA and cannot be used when the null hypothesis is rejected in Tajima's relative rate test. This technique requires calibration from the fossil record. For 10 points, name this technique based on Kimura's neutral theory, used to estimate divergence times and provide a timescale to phylogenetic trees.
In 2010, Sperling et al used microRNA screens and this technique to discover the "spicule gap" in demosponges.
molecular clocks [accept descriptive answers like dating divergence times before mentioned; accept ML/SRDT clocks; prompt on partial answer; prompt on answers like "making phylogenetic trees" or "rooting"; prompt on answers involving "fossils" before mentioned; prompt on "genomics" or any answers related to gene sequencing]