The role of this pathway in Clara cell regeneration was established by Roel Nusse, One non-canonical example of this pathway activates the enzymes CamKII and PKC enzymes through PDE6, while another interacts with the JNK and PCP pathways; both of these pathways play a role in convergent extension and planar cell polarity.
The role of this pathway in Clara cell regeneration was established by Roel Nusse, One non-canonical example of this pathway activates the enzymes CamKII and PKC enzymes through PDE6, while another interacts with the JNK and PCP pathways; both of these pathways play a role in convergent extension and planar cell polarity. This pathway is named for a related family of growth factors that, canonically, bind to LRP and a cysteine-rich segment of Frizzled in developing cells. This binding activates Disheveled, which inhibits GSK-3 and leads to a build up of beta-catenin. That protein activates target genes responsible for developing dorsal structures. Like Hedgehog and Notch, this pathway is active during development. For 10 points, name this signaling pathway that is vital in establishing the dorsal-ventral axis.
The role of this pathway in Clara cell regeneration was established by Roel Nusse, One non-canonical example of this pathway activates the enzymes CamKII and PKC enzymes through PDE6, while another interacts with the JNK and PCP pathways; both of these pathways play a role in convergent extension and planar cell polarity.
Wnt signaling pathway