One of the main arguments in favour of the Initiative for the Integration of Regional Infrastructure in South American IIRSA project is that, historically, the regions of Beni and Pando have been isolated from the rest of the country and that this road would enable both provinces and the North of Bolivia to have better access to important cities such as Cochabamba and La Paz.
Entre los principales argumentos a favor del TIPNIS se señala que las regiones del Beni y Pando han estado históricamente aisladas del resto del país y que esta carretera permitirá que ambas provincias y el Norte de Bolivia tengan un mejor acceso hacia ciudades importantes como Cochabamba o La Paz.