Propolis's toxicity has not been extensively researched and few studies on live cells have been recorded. This is one of the reasons behind the use of polymorphonuclear leukocytes in the present experiment since they are easily recoverable cells of peripheral blood as well as second line of defense of the human body; they are equally involved in anti-bacterial and anti-infectious processes, which are essential characteristics mentioned here for propolis as well.
Su toxicidad ha sido poco investigada, encontrándose una limitada cantidad de estudios realizados en células vivas por tal razón se utilizaron leucocitos polimorfonucleares neutrófilos, células fácilmente recuperables de la sangre periférica que son la segunda línea de defensa del cuerpo humano; y están implicadas en los procesos antiinfecciosos y antibacterianos, características primordiales mencionadas también para el propóleo.