In 1991 Wotherspoon and his collaborators were the first to demonstrate the close relation which exists between Helicobacter pylori and MALT lymphomas. They described H. pyloris presence in practically all of the patients they studied who had MALT lymphomas 7. Two years later they demonstrated regression of tumors in 5 of the six patients they were following after eradication of the bacteria 8.
En 1991, Wotherspoon y colaboradores fueron los primeros en demostrar la estrecha relación que existe entre el Helicobacter pylori y el linfoma MALT; describieron su presencia en prácticamente todos los pacientes con linfoma MALT 7 y dos años después demostraron la regresión tumoral en 5 de 6 pacientes luego de la erradicación de la bacteria 8.