The change in the epidemiology of C. difficile infections has been attributed to a new hypervirulent strain: NAP1/ BI/027. This strain was first isolated in 1984 at which time it was only rarely detected in humans.
El cambio epidemiológico de la infección por C. difficile es atribuido a una nueva cepa hipervirulenta: NAP1/BI/027, aislada por primera vez en 1984, raramente detectada en humanos e inicialmente sensible a quinolonas 1, 5.