Dr. Otto, in 1830 suggested that premature suture closure caused deformities. Based on that, Dr. Virchow published his research on deformities which stemmed from scientific studies.
En 1830, Otto postuló que el cierre prematuro de suturas provocaba deformidades, con base en eso, Virchow publicó su trabajo acerca de deformidades que provenían de estudios científicos.