The biosynthesis of monolignols requires the participation of 10 enzymes: phenylalanine amonnia lyase PAL, three cytochrome P450-monoxygenases cinnamate-4-hydroxilase, p-coumarate-3-hydroxylase and ferulate-5-hydroxylase, C4H, C3H, and F5H, respectively, two methyltransferases caffeoyl-CoA-O-methyltransferase and caffeic acid caffeate-O-methyltransferase, CCoAOMT and COMT, respectively, and two oxidoreductases cinnamoyl-CoA-reductase and cinnamyl-alcohol dehydrogenase, CCR and CAD, respectively, as well as the enzymes 4-coumarate CoA ligase 4CL and hydroxicinnamoyl-CoA shikimate HCT, which are required for the synthesis of the different intermediaries that act as substrates in later reactions .
Para la biosíntesis de monolignoles se requiere de la participación de 10 enzimas: fenilalanina amonio liasa PAL, tres citocromo P450-monoxigenasas cinamato-4-hidroxilasa, p-cumarato-3-hidroxilasa y ferulato-5-hidroxilasa, C4H, C3H y F5H, respectivamente, dos metiltransferasas cafeoil-CoA-O-metiltransferasa y ácido caféico-O-metil-transferasa, CCoAOMT y COMT, respectivamente y dos oxidoreductasas cinamoil-CoA-reductasa y cinamoil alcohol deshidrogenasa, CCR y CAD, respectivamente, además de las enzimas 4-cumarato CoA ligasa 4CL e hidroxicinamoil-CoA shikimato HCT, las cuales son requeridas para la síntesis de los diferentes intermediarios que sirven como sustratos en reacciones posteriores .