Nevertheless, there was evidence of higher susceptibility to disease in patients who did smoke; this could be due to systemic effects which impacted on immune response and caused more severe clinical risk of periodontal disease.
Sin embargo, existe evidencia en la susceptibilidad a enfermar mayor en pacientes que fuman debido al efecto sistémico que repercute en la respuesta inmunitaria y provoca un riesgo clínico de enfermedad periodontal más grave.