When ganglion cells are not observed in a biopsy and there are islands of squamous epithelium or sphincter muscle fibers, it is the unequivocal signature that the sample was obtained from below the pectinate line. This should always be reported as a sample which is inadequate for diagnosis.
Cuando en una biopsia no hay células ganglionares y se observan islas de epitelio escamoso o fibras musculares del esfínter, es firma inequívoca de que se obtuvo debajo de la línea pectínea y debe siempre informarse como inadecuada para diagnóstico.