Its main function is as a linking protein to heme 17-19. HO-1 has a high concentration in the spleen and is responsible for hemes quick elimination from circulation. It seems that HO-2 can protect neurons from oxidative damage 20.
La HO-1 tiene elevadas concentraciones en el bazo y es la responsable de la rápida eliminación del hem de la circulación y la HO-2, al parecer, protege las neuronas del daño oxidativo 20.