The large blood vessels usually exit the muscularis propria and penetrate the submucosal layer vertically perpendicular to the muscularis propria. They then branch out horizontally. Most of them form a network in the middle submucosal layer.
Los grandes vasos sanguíneos normalmente salen de la capa muscular propia y atraviesan la capa submucosa de forma perpendicular-vertical a la capa muscular propia; luego se ramifican de forma horizontal-paralela principalmente en la capa submucosa media y forman una gran red.