Oral tapentadol is eliminated mainly by hepatic glucuronization by UGT1A9 and UGT2B7 transferases uridina 5′-difosfo-glucuronosil transferases 13,30.
El tapentadol administrado de manera oral se elimina, principalmente, por glucuronidación hepática vía transferasas UGT1A9 y UGT2B7 uridina 5′-difosfo-glucuronosil transferasas 13,30.