15% to 20% are familial cases. The remaining cases occur sporadically, but one third are develop as fulminant hepatitis, and cases of hepatocellular carcinoma have been reported in late stages 14.
Entre 15-20% son casos familiares, los restantes ocurren en forma esporádica y la tercera parte de ellos cursa como una hepatitis fulminante y se han descrito casos de hepatocarcinoma en fases tardías 14.