Dr. Liu et al. based on immune-histochemical and enzyme-histochemical tests, described that GCPG multi-nucleated giant cells possessed cellular characteristics which were compatible with osteoclasts, cells responsible for bone resorption and remodeling of the human skeletal system.
Liz y cols a través de pruebas inmunohistoquímicas y enzimas histoquímicas, describieron que las células gigantes multinucleadas del GPCG poseen características celulares compatibles con las de los osteo-clastos, células responsables de la reabsorción y remodelación ósea del sistema esquelético humano.