The first report to appear in scientific literature of an ocular globe prosthesis belongs to Ambroise Paré, 1591, with the description of two types of ocular prostheses: the Hyplèpharon and the Ecblèpharon, the first fitted under the eyelids in the conjunctival sac, and the second one consisting on a strip of leather, with eyes and eyelids painted upon it, which was held with a metallic band around the head.
El primero, se encajaba bajo los párpados en el saco conjuntival y el segundo, consistía en un pedazo de cuero con el ojo y los párpados pintados, que se sujetaba mediante una banda metálica alrededor de la cabeza.