The risk of mortality in anemic patients decreases when adjusted for confounding variables such as age, peripheral vascular disease, renal failure and a history of myocardial infarction or chronic obstructive pulmonary disease COPD.Even though it is not easy to control the bias associated with the indication in the studies that report an association between anemia and adverse events in patients who need to be transfused, it is important to highlight the number of studies in which transfusion is associated with adverse events, such as: pneumonia, mediastinitis, renal dysfunction, mortality and decreased survival. 1. Carson JL, Duff A, Poses RM, et al. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet. 1996;348:1055-60. 2. Groenveld HF, Januzzi JL, Damman K, et al. Anemia and mortality in heart failure patients a systematic review and meta-analysis. J Am Coll Cardiol. 2008;52:818-27.
El riesgo de mortalidad en los pacientes anémicos desaparece cuando se ajusta por variables de confusión, como la edad, la enfermedad vascular periférica, la disfunción renal, el infarto de miocardio previo o la enfermedad pulmonar obstructiva crónica.