Studies conducted in Europe report adherence rates of between 20 and 100%. The proposed causes of non-adherence were differences between the patient being treated and the condition described in the guidelines, the presence of kidney or liver failure, the unavailability or excessive costs of specific antibiotics, and differences between local flora and international recommendations.
Estudios realizados en Europa reportan tasas de adherencia entre 20 y 100%; las causas propuestas fueron: diferencia entre el paciente a tratar y la patología descrita en la guía; presencia de insuficiencia renal o hepática; no disponibilidad o costes excesivos de antibióticos específicos; diferencias entre flora local y recomendaciones internacionales.