Vitamin B12 deficiency secondary to atrophy of the oxyntic mucosa located in the gastric body, and which has an autoimmune cause type A gastritis results in a type of megaloblastic anemia known as pernicious anemia. It is responsible for about 20% of all cases of vitamin B12 deficiency.
La anemia megaloblástica por deficiencia de vitamina B12, secundaria a la atrofia de la mucosa oxíntica localizada en el cuerpo gástrico y de causa autoinmune gastritis tipo A, es conocida como anemia perniciosa y es la responsable de cerca del 20% de los casos del déficit de vitamina B12.