Toriello suggests the presence of vascular disruptive mechanisms in early embryonic stages, the same as Whitley and Gorlin who suggested a vascular compromise in watershed areas during development periods.
La hipótesis de Toriellosugiere mecanismos disruptores vasculares en etapas tempranas embrionarias, al igual que Whitley y Gorlinquienes sugirieron un compromiso vascular en áreas ''watershed'' durante periodos del desarrollo.