Although procoagulant factor deficiency in chronic liver disease may be responsible for the tendency of cirrhosis patients to bleed, decreased production of endogenous anticoagulants such as protein C, protein S, thrombomodulin and tPA has been also demonstrated 38, 39.
La deficiencia de factores procoagulantes en enfermedad hepática crónica pudiese ser la responsable de la tendencia al sangrado de los pacientes con cirrosis.