In contrast, cytotoxic oedema is defined as swelling involving neurons, glia and endothelial cells due to an energy failure that affects both the grey and the white matter; it happens when there is water accumulation in the cytosol as a result of deranged osmolyte distribution.
En cambio, el edema citotóxico se explica como una tumefacción celular que envuelve a la neurona, la glía y a las células endoteliales por falla energética, afectando tanto la sustancia gris como la blanca.