In addition, increased expression of the inducible enzyme COX-2 secondary to H. pylori infection is considered to be involved in the risk of developing CRC, since 48, an association between the expression and tissue activity of COX-2 and development and progression of colon cancer and other neoplasias has been shown to exist 60, 61.
Existe una asociación entre la expresión y actividad tisular de COX-2 con el desarrollo y evolución del cáncer de colon y de otras neoplasias 60, 61.