Patients with this genotype and a tobacco addiction were significantly associated with high GC risk OR=3.0. In this case it was caused by a the greater genotoxic load contributed by the cigarette smoke.
Al tener en cuenta este genotipo y el tabaquismo, se halló asociación significativa con el riesgo a CG OR = 3,0, en este caso debido a la mayor carga genotóxica aportada por el humo del cigarrillo.