Children that have suffered from constipation since the neonatal period, or whose constipation is unresponsive to treatment and persists with chronic symptoms, must be tested for enteric neuropathy and must have rectal biopsies taken.
Aquellos niños que tienen estreñimiento desde el periodo neonatal o que persisten con síntomas crónicos que no responden al tratamiento, deben ser remitidos para estudio de neuropatía entérica con toma de biopsias rectales.