Its origin is multifactorial: increased hepcidin synthesis, inhibition of the erythropoietin synthesis and the erythroid proliferation, and increased hematophagocytosis.
Su origen es multifactorial: aumenta la síntesis de hepcidina, se inhiben la síntesis de eritropoyetina y la proliferación eritroide, y aumenta la hematofagocitosis.