In the face of growing resistance to Clarithromycine and increasing failure of standard triple therapy, other therapies which have been second choices or rescue therapies are now being given consideration. Among these are quadruple therapies in which a PPI is added to the classic trio of bismuth salts, tetracycline and methronidazolee for either seven or fourteen days 12, 13, 16. Success rates for this therapy have varied between 57% and 91%, with an average rate of 77% 59.
Ante el creciente aumento de la resistencia a claritromicina y el fracaso de la TTE, han aparecido otras terapias alternativas de segunda elección o terapias de rescate, como son las terapias cuádruples que consisten en adicionar un IBP a la terapia clásica de bismuto, tetraciclina y metronidazol, durante 7 a 14 días 12, 13, 16, cuyo éxito varía entre 57 a 91%, con promedio de 77% 59.