A meta-analysis which included four RCT and 476 patients AMSTAR score 8/11 showed that patients diagnosed with primary syphilis who had been treated with azithromycin had a similar serological cure rate when compared to patients who were treated with penicillin G benzathine OR 0.68: 0.29-1.6195% IC 72.
Un metaanálisis 72, que incluyó 4 ECA y un total de 476 pacientes, con un puntaje AMSTAR 8/11, mostró que los pacientes con diagnóstico de sífilis primaria tratados con azitromicina muestran frecuencias similares de cura por serología en comparación con pacientes tratados con penicilina G benzatínica RR = 0,68; IC 95%: 0,29-1,61.