The Jarisch-Herxheimer reaction is one of the most frequently occurring ones, involving an acute febrile illness, accompanied by severe headache and myalgia 24 hours after beginning treatment for syphilis; 50% incidence has been reported in patients suffering primary syphilis treated with penicillin G, with resolution occurring within 12-24 hours of its appearance 92.
Una de las reacciones más frecuentes es la de Jarisch-Herxheimer, manifestación aguda de tipo febril acompañada por cefalea, mialgia o fiebre posterior a las 24 horas de inicio del tratamiento para sífilis.