These fibres are activated by sensitizing substances, and the toxin is involved by reducing the release of bradykinins, serotonin, potassium, prostaglandin E2, glutamate, substance P, and calcitonin gene-related peptide CGRP.
Estas fibras se activan por sustancias sensibilizantes donde interviene la toxina al disminuir la liberación de bradicininas, serotonina, potasio, prostaglandina E2, glutamato, sustancia P y péptido relacionado con el gen de calcitonina CGRP.