The first and third trimesters were the most prone to exacerbations, generally being related to infectious diseases and emotional disturbances, even though cases were mentioned which were caused by summer heat.
Las exacerbaciones son más propensas en el primero y en el tercer trimestre, relacionados generalmente con enfermedades infecciosas y disturbios emocionales, aunque se mencionan casos por el calor del verano.