They acknowledged them as the first perceivable signs of the disease. The disease is responsible for a defect in teeth mineralization, which causes a poorly mineralized and dysplastic dentin, with a non-calcified matrix which is called globular dentin.
La enfermedad es responsable de un defecto en la mineralización de los dientes, que ocasiona una dentina pobremente mineralizada y displásica, con una matriz no calcificada que es llamada dentina globular, así como defectos tubulares que alcanzan la unión amelodentinaria.