This wide range is explained by the absence of one single criterion for defining CKD and by the fact that diagnosis of CKD is determined by equations which depend on levels of creatinine. These levels overestimate kidney functioning due to the kidney's small muscle mass, so that the kidney has lower yields of creatinine as a consequence.
Este amplio rango es explicado por la ausencia de un criterio único para definirla y debido a que generalmente esta es determinada por ecuaciones que dependen del nivel de creatinina, que sobreestiman la función renal debido a la baja masa muscular y por tal razón hay una menor generación de creatinina.