The mechanisms by which bilirubin reacts with oxygen radicals are not completely understood, however its hydrophobic tetrapyrrole structure has been reported to be an inhibitor of NADPH oxidase and protein kinase C PKC among other mediators of pro-arteriogenic factors 58-60.
Los mecanismos por los cuales la bilirrubina reacciona con los radicales de oxígeno no están completamente dilucidados, sin embargo, su estructura tetrapirrólica hidrofóbica ha sido reportada como inhibidor de la NADPH oxidasa, protein cinasa C PKC, entre otros mediadores de factores proaterogénicos 58-60.