CPGs were first introduced between the 1950s and the 1970s and gained significant momentum starting in the 1980s, culminating with the mandate from the Agency for Health Care Research and Quality AHRQ requiring the development of clinical guidelines in the USA 4.
Las GPC se empiezan a producir entre los años cincuenta y setenta, con un importante incremento a partir de los años ochenta que finaliza con el mandato de la Agency for Health Care Research and Quality AHRQ de producir guías clínicas en Estados Unidos 4.