Previous studies suggest that women with NSIL and positive for HR-HPV have a higher risk of developing cervical lesions. Koutsky et al. observed that 30% of women with a normal cytological diagnosis and positive for HR-HPV developed intraepithelial lesions in the course of two years.
Estudios previos sugieren que mujeres con NSIL y positivas para HR-HPV poseen mayor riesgo de desarrollar lesiones de cuello uterino, observando Koutsky et al, que un 30% de mujeres con diagnóstico citológico normal y positivas para HR-HPV desarrollaron lesión intraepitelial en el transcurso de 2 años.