Certain polymorphisms of Toll-Like Receptor 4 3725 G/C have been found associated with increased risk of gastric atrophy 99 as well as GC 100. This indicates that this variation of innate immune system transmembrane protein recognizes pathogenic molecular patterns. Thus they are host factors involved in the response and outcome of infection.
Determinados polimorfismos del receptor "Toll-like 4" TLR4+3725 G/C se han encontrado asociados con mayor riesgo de atrofia gástrica 99 y de CG 100, indicando que esta variación de proteínas transmembrana de reconocimiento de patrones moleculares de patógenos del sistema inmune innato son factores del huésped que participan en la respuesta y desenlace de la infección.