Consequently, we do not know if genetic or environmental factors contribute to different clinical behaviors of IBD here, than they do among European and American patient populations. 1. Bernstein CN, Blnachard JF, Rawsthorne P, Wajda A. Epidemiology of Crohns disease and ulcerative colitis in a central canadian province: A population-based study. Am J Epidemiol 1999; 149: 916-24. 2. Loftus Jr EV, Silverstein MD, Sandborn WJ, Tremaine WJ, Harmsen WS, Zinsmeister AR. Ulcerative colitis in Olmsted County, Minnesota, 1940-1993: Incidence, prevalence and survival. Gut 2000; 46: 336-43. 3. Loftus Jr EV, Silverstein MD, Sandborn WJ, Tremaine WJ, Harmsen WS, Zinsmeister AR. Crohn`s disease in Olmsted County, Minnesota, 1940-1993: Incidence, prevalence and survival. Gastroenterology 1998; 114: 1161-8. 4. Loftus EV Jr. Clinical epidemiology of inflammatory Bowel Disease: Incidence, prevalence and environmental Influences. Gastroenterology 2004; 126: 1504-17. 6. J Satsangi, M S Silverberg, S Vermeire, and J-F Colombel. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006; 55: 749-753. 7. Wolters FL, Russel MG, Langholz E, Vermiere S, Moun B, et al, on behalf of the European Collaborative study Group on Inflammatory Bowel Disease EC-IBD. Phenotype at diagnosis predicts recurrence rates in Crohns disease. Gut 2006; 55: 1124-1130. 8. Solberg IC, Vatn MH, Moum B, et al, and the IBSEN Study Group. Clinical Course in Crohns disease: Results of a Norwegian population-based ten-year follow-up study. Clin Gastroenterol Hep 2007; 5: 1430-1438. 9. Romberg- Camps MJL, Dagnelie PC, Kester ADM, Wolters FL, et al. Influence of Phenotype at diagnosis and of other potential prognostic factors on the course of inflammatory bowel disease. Am J Gastroenterol 2009; 104: 371-383. 10. Langholz E, Munkholm P, Davidsen M, Binder V. Course of ulcerative colitis: analysis of changes in disease activity over year.Gastroenterology1994; 107: 3-11. 11. Höie O, Wolters F, Riis L, Langholz E, et al, on behalf of the European Collaborative Study Group of Inflammatory Bowel Disease EC-IBD. Ulcerative colitis: Patient Characteristics may predict 10-Yr Disease recurrence in a European-Wide population-based cohort. Am J Gastroenterol 2007; 102: 1692-1701. 12. Solberg IC, Lygren I, Jahnsen J, et al, and the IBSEN Study Group. Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort IBSEN Study. Scand J Gastroenterol 2009; 44: 431-440. 13. Lok Ka-Ho, Hung Hiu-Gong, Ng Chi-Ho, et al. Epidemiology and clinical characteristics of ulcerative colitis in Chinese population: Experience from a single center in Hong Kong. J Gastroenterol and Hepatol 2008; 23: 406-410. 14. Bitton A, Peppercon MA, Antonioli DA, et al. Clinical, Biological and Histologic parameters as predictors of relapse in ulcerative colitis. Gastroenterology 2001; 120: 13-20. 15. Ananthakrishnan AN, Issa M, Binion DG, et al. History of medical hospitalization predicts future need for colectomy in patients with ulcerative colitis. Inflamm Bowel Dis 2009; 15: 176-181. 16. Farmer RG, Easley KA, Rankin GB. Clinical patterns, natural history, and progression of ulcerative colitis: A long term follow up of 1116 patients. Digest Dis Sci. 1993; 38: 1137-1146. 17. Linares de la Cal JA, Cantón C, Hermida C, Pérez-Miranda M, Maté-Jiménez J. Estimated incidence of inflammatory bowel disease in Argentina and Panama 1987-1993. Rev Esp Enferm Dig 1999; 914: 277-86. 18. Figueroa C, Quera R, Valenzuela J, Jensen Ch. Enfermedades inflamatorias intestinales: Experiencia de dos centros chilenos. Rev Méd Chile 2005; 133: 1295-1304. 19. Geboes K, Colombel JF, Sandborn WJ, Riddell RH, and the pathology task force of the IOIBD. Indetreminate colitis: A review of the concept-whats in a name? Inflamm Bowel Dis 2008; 14: 850-857. 21. Sawczenko A, Sandhu BK. Presenting features of inflammatory bowel disease in Great Bretain and Ireland. Arch Dis Child 2003; 88: 995-1000. 22. Vind I, Riis L, Jess T, Knudsen E, Pedersen N, Elkjaer M, et al. Increasing incidences of inflammatory bowel disease and decreasing surgery rates in Copenhagen City and County: 2003-2005: a population study from the Danish Crohn colitis database. Am J Gastroenterol 2006; 101: 1274-82.
Por todo lo anterior no sabemos si factores genéticos o ambientales contribuyan a un comportamiento clínico diferente de nuestros pacientes con enfermedad inflamatoria intestinal, comparados con poblaciones europeas y de Norteamérica.