For patients with cholestatic diseases transplants are indicated in moderate to severe cases hyperbilirubinemia, untreatable pruritus, and in persistent cholangitis specifically in primary sclerosing cholangitis when cholangiocarcinoma has been ruled out and when there is a dominant stenosis that cannot be solved with interventional treatment.
En las enfermedades colestásicas se indica en los casos de hiperbilirrubinemia moderada a severa, prurito intratable, colangitis recurrente y específicamente en colangitis esclerosante primaria cuando exista una estenosis dominante que no se resuelva con manejo intervencionista, siempre y cuando se descarte colangiocarcinoma.