This was not difficult to achieve in the case of a bacteria, because all one had to do was to add salts to a test tube and to produce heat shock so that the pores in the bacteria's membrane would open and the DNA could get in.
Esto no era difícil de conseguir cuando se trataba de hacerlo en una bacteria, pues bastaba con agregar algunas sales al tubo de ensayo y producir un shock térmico para que la bacteria abriera los poros de su membrana y el ADN ingresara.