The other thing that could explain the significant number of patients with confirmed intestinal metaplasia without the presence of Helicobacter Pylori is the possibility of bacterial migration patterns that were not detected by routine biopsy, but which generate changes in the mucosa associated with subsequent development of pre-neoplastic lesions and subsequent development of cancer.
Lo otro que podría explicar esto sencillamente es que se puedan generar probables patrones de migración de la bacteria donde se crean los cambios asociados en la mucosa para el posterior desarrollo de lesiones preneoplásicas y de cáncer pero que no se hayan detectado mediante la biopsia de rutina.