Holland et al conducted research on the reaction of periapical tissue in dog teeth filled with gutta-percha and Ketac-Endo as well as ProRoot MTA. After a six month period they performed a histopathological exam.
Holland et al. investigaron la reacción del tejido periapical en dientes de perro obturados con gutapercha y Ketac-Endo y ProRoot MTA luego de un periodo de seis meses realizaron un examen histopatológico.