Both originate in B-cells of the marginal zone and both share morphological, immunological and phenotypical characteristics, but extranodular B-cell lymphoma are considered to be a different entity because of their unusual pathogenesis 4.
Ambos se originan en las células B localizadas en la zona marginal y comparten características morfológicas e inmunofenotípicas, pero los extraganglionares dada su inusual patogenia son considerados una entidad diferente 4.