Individuals that present at least one functional allele are called GSTT1 positive and those that have a complete lack of any copy of the gene are GSTT1*0 null homozygote genotype. They have no detectable enzymatic activity, and they present detoxifying deficiencies. As a result, this genotype has been associated with the risk of developing diverse neoplastic pathologies such as GC 20-24.
Los individuos que presentan al menos un alelo funcional se denominan GSTT1 positivos y los que carecen por completo de alguna copia del gen son de genotipo GSTT1*0 homocigotos nulo, no tienen actividad enzimática detectable, presentan deficiencias desintoxicadoras 19 y debido a esto se han asociado con riesgo a desarrollar diversas patologías neoplásicas, entre ellas el CG 20-24.