The basic principles of antiophidic therapy, discovered in the late XIX century, have remained unchanged: the antivenoms are prepared from the plasma of animals immunized with one or more venoms, and which develop an adequate antibody response to achieve their neutralization.Technologically, progress has being made in the purification of antibodies out of complete plasma, when compared to the rudimentary original methods.
Tecnológicamente, se han logrado avances en la purificación de los anticuerpos a partir del plasma completo, en comparación con los rudimentarios métodos originales.