A key indicator for pathological diagnosis of fibrosis and cirrhosis is in inflammation. Its location can vary from portal to periportal, periductal, intracinar or subsinusoidal. The distribution of the inflammation can be focal, diffuse, segmental or lobular. It can vary from severe to mild. Severe fibrosis with incomplete or complete cirrhotic nodules is the other key indicator.
Al igual que lo descrito con la inflamación, la localización portal, periportal, periductal, intracinar o subsinusoidal, su distribución focal, difusa, segmentaria o lobular y la cantidad o severidad de la fibrosis leve, moderada o severa conformando nódulos cirróticos incompletos o completos; son los indicadores claves en el diagnóstico patológico.