The Study Comparing Cyclosporine With Infliximab in Steroid-refractory Severe Atacks of Ulcerative Colitis CYSIF was a randomized controlled study which compared the efficacy of IFX vs. cyclosporine rescue therapy in 111 patients with acute severe ulcerative colitis who were refractory to treatment after 5 days of intravenous steroids. It found response rates on day 7 of 86% for IFX and.
El estudio "CYSIF", aleatorizado y controlado, comparó la eficacia de IFX vs. ciclosporina como terapia de "rescate" en 111 pacientes con CUAS refractarios a tratamiento con 5 días de esteroides intravenosos, encontrando una tasa de respuesta al 7° día de 86% vs.