In macrovesicular steatosis a large fat vacuole moves the nucleus towards the periphery. This occurs in both alcoholic and non-alcoholic fatty liver disease as well as in obesity, diabetes, diseases associated with abnormal lipid metabolism, hepatitis C, malnutrition, and drug toxicity.
En la esteatosis macrovesicular hay una gran vacuola grasa que desplaza el núcleo hacia la periferia la vemos en enfermedad hepática grasa alcohólica o no alcohólica, obesidad, diabetes, enfermedades relacionadas con anomalías del metabolismo de los lípidos, hepatitis C, malnutrición o toxicidad medicamentosa.