There are articles in the medical literature demonstrating its therapeutic effectiveness for the treatment of both acute and chronic pain 2. As concerns the possibility of seizures resulting from the use of Tramadol, the study by Quintero reference 12 is not conclusive as to whether this medication is or is not responsible for their occurrence.
No existe información acerca de su eficacia y tolerabilidad en estados de dolor crónico, como tampoco se conocen datos clínicos en pacientes ancianos, ni detalles específicos del potencial de interacción fármaco-fármaco 4.