During the early stages of research Dr. Bolaños and his small group of collaborators, which formed the initial staff of CPI, conducted research on several fundamental questions. This was necessary to structure the knowledge platform that would allow them to address the snakebite problem in a comprehensive manner in order to implement the production of the first indigenous antivenoms.
Para llegar a implementar la producción de los primeros antivenenos autóctonos, el Dr. Bolaños y su reducido grupo de colaboradores -que formaron el personal inicial del ICP-, se dedicaron en las primeras etapas a investigar sobre varias preguntas fundamentales, necesarias para estructurar la plataforma de conocimientos que permitiría enfrentar el problema del ofidismo de manera comprensiva.