It might be mentioned that Dr. Demirjian observed that mechanisms which control dental development are independent from somatic and sexual maturity, and that they appear to be greatly influenced by etiological factors such as fissures.
Cabe destacar que Demirjian, observó que los mecanismos que controlan el desarrollo dental son independientes de la madurez sexual y somática, y que éstos parecen estar altamente influenciados por factores etiológicos como la fisura.