Approximately 25% of gastric GISTs and 50% of small intestine GISTs are clinically malignant. They metastasize primarily within the abdominal cavity and liver, less commonly in soft tissues, lymphatic skin, ganglia, lung and bone.
Aproximadamente, 25% de los GIST gástricos y 50% de los GIST del intestino delgado son clínicamente malignos y desarrollan metástasis principalmente en la cavidad abdominal e hígado, menos comúnmente a tejidos blandos, piel, ganglios linfáticos, pulmón y hueso.