Drs. Robbins & Cotran defined this type of granuloma as a focus of chronic inflammation consisting of microscopic aggregation of macrophages which transform into epithelial-like cells, surrounded by a rim of mononuclear leucocytes, mainly lymphocytes, as well as occasionally plasmatic cells.
Robbins & Contra definen el granuloma como un foco de inflamación crónica que consiste en la agregación microscópica de macrófagos que se transforman en células semejantes a las epiteliales, rodeadas por un collar de leucocitos mononucleares, principalmente linfocitos y ocasionalmente células plasmáticas.