It is currently recognized that the cause of coagulopathy is multifactorial and that it is an early primary phenomenon caused by the activation of the thrombomoduline and protein C system resulting in systemic anticoagulation, in addition to increased fibrinolytic activity.
Actualmente se sabe que la causa de la coagulopatía es multifactorial y que es un fenómeno primario temprano producido por la activación del sistema trombomodulina y proteína C que conduce a una anticoagulación sistémica; sumado a este fenómeno existe un aumento de la actividad fibrinolítica.