The majority of PPIs are metabolized in the liver by Cytochrome P450 through the CYP2C19 enzyme 30, however Rabeprazole is a PPI which is not involved in this enzyme system 31.
La mayoría de los IBPs son metabolizados en el hígado por el citocromo P450, por el sistema enzimático CYP2C19 30, aunque el rabeprazol no involucra este sistema enzimático 31.