He's referring to the pie.
House! I'm not gonna tell you a third time. Do not screw this up. Because I really don't wanna clean up the mess.
She doesn't sleep with Chase. We don't know that.  Hey! Eating pie in here.
She doesn't sleep with Chase. We don't know that.  Hey! Eating pie in here. [SEP] House! I'm not gonna tell you a third time. Do not screw this up. Because I really don't wanna clean up the mess. [SEP] He's referring to the pie.