Ayahuasca is a term used to define a drink that many different ancient and current cultures prepare differently.  Some use Chacruna, or Chaliponga leaves – others use Acacia Confusa tree bark or Mimosa Hostillis root bark to fulfill one part of the Ayahuasca drink.  This part MAY also contain San Pedro cactus or Psilocin mushrooms.   It MUST also contain an MAOI which slows the metabolism of all the aforementioned plants.  The most popular MAOI is Banisteriopsis caapi or Banisteriopsis muricata however the MAOI can be interchanged with Syrian Rue.   That is Ayahuasca.  Syrian Rue seeds and Banisteriopsis vines contain very similar MAOI’s which can be combined with other weaker MAOIs such as Passion Flower leaf and vine extract, Cacao, and Golden Milk which is Turmeric and Black pepper.  The complexity of the brew varies greatly and so do the effects of the ayahuasca.

I watched Hamilton Morris of Hamilton’s Pharmacopeia drink an extract of Ayahuasca vine, then wait an hour before drinking the water extract of Chacruna leaves.  Typically the two plants, your MAOI and your neurotransmitters, are brewed together into 1 drink confusingly called “Ayahuasca” which is also the name of the vine.  Most people are referring to the mixed plants in 1 drink when they use the word Ayahuasca.  Ayahuasca brews often contain multiple plant sources of neurotransmitters.  It has been discovered that to get the most neurotransmitters to the brain, the MAOI should already be in effect, therefore the mixed drink ironically called Ayahuasca is slightly more effective when brewed in 2 drinks.

An extract can be made from EITHER Caapi OR Syrian Rue.  The effects are not identical however the effects are of the same sacred essence and both preparations have been to blame for profound insights and psychological advancements.  The two plants are interchangeable.  Ive experienced Yopo snuff made BOTH from the ashes of a burnt Conch shell AND from lime, or Calcium Hydroxide, or CaOH  – this:


Read about Calcium Hydroxide here:

Shamans tend to get zealous for the way that they prepare medicine from sacred plants.  Many people have written on this topic.  To avoid any argument with anyone who takes plant medicine serious like i do, i would prefer that you consider a few of these information sources rather than consider anything that i have to say on this topic.

Check out this video about what Aya is:  https://www.youtube.com/watch?v=uReTtIAVAfY

Learn from others also if you are wanting to know everything that you possibly can about Ayahuasca.  Here’s two more:
In Ayahuasca Analogs (Anahuasca) As we have seen, Peganum harmala contains MAO-inhibiting beta-carbolines, and thus may be useful as an ayahuasca analog. Crush 2-5 g Peganum harmala seeds to a pot. According to Shulgin, 1 teaspoon rue seeds weighs 3 grams and contains 60-180 mg alkaloids.
Peganum harmala is a perennial plant that has a lot in common with the psychoactive vine from Amazonia, ayahuasca. The two entheogens share a similar molecule profile, and both have been associated with many types of healing and spirituality in different cultures. While ayahuasca is more well-known on the internet today, its “sister,” Peganum harmala, deserves more attention than it gets. This article explores the plant’s fascinating history, array of uses, and medicinal potential.  https://kahpi.net/syrian-rue-peganum-harmala-ayahuasca/