Antiparasitic drugs

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  1. 6 ideal characteristics of antiparasitic drugs
    • selective toxicity
    • does not induce resistance
    • economical
    • effective and easy to apply
    • fragrant odor
    • environmentally safe
  2. term for non-perscription drugs
    over the counter (OTC)
  3. compound that kills various types of internal parasites
  4. a drug that kills worms
  5. a drug that paralyzes the worm and is often passed with the parasite still alive
  6. "Happy Jack"
  7. if happy jack was not dosed properly then it could result in
    piperzinc toxicosis syndrome
  8. what is the name for the group of drugs that all end with the suffix -azole
  9. What are the 8 drugs that make up the benzimidazoles
    • Parbendazole
    • Albendazole
    • Cambenazole
    • Thiabendazole
    • Fenbendazole
    • Mebendazole
    • Oxibendazole
    • Oxfendazole
  10. What was the first benzimidazole and what was it called
    Thiabendazole - TBZ
  11. Panacur
  12. Telmin
  13. Filaribits plus
    Diethylcarbamazine citrate/oxibendazole
  14. what was the first benzimidazole to kill Strongylus vulgaris including its S4 migratory form
  15. task
  16. combot
  17. Equigard
  18. Eqvalan
  19. What is a neurotransmitter that is released by the autonomic nervous system as well as the cranium and spine
    Acetylcholine (ACH)
  20. What are two neurotransmitters of the CNS
    • Glutamate (glutamic acid)
    • Aspartate (aspartic acid)
  21. What are two important inhibitory neurotransmitters
    • Gamma aminobutyric acid (GABA)
    • Glycine
  22. Strongid T
    Pyrantel tartrate
  23. Strongid C
    Pyrantel pamoate
  24. This drug is considered the safest of all the veterinary products for parasites in small animals
    • Pyrantel pamoate
    • Pyrantel tartrate
  25. drontal
  26. Drontal plus
    Praziquantel/febantel/pyrantel pamoate
  27. this is one of the oldest groups of insecticides but is very resistant to bidegradation.
    Chlorinated hydrocarbons (Lindane)
  28. Lindane
    Chlorinated hydrocarbons
  29. What are the two class of Acetylcholine receptors
    • Muscarinic receptors
    • Nicotinic receptors
  30. If you block the acetylcholineesterase at the muscarinic receptors, the stimulation of the receptors with continue and the animal will suffer from these symptoms
    • SLUDDE
    • Salivation, lacrimation, urination, defecation, dyspnea, emesis
  31. Where are muscarinic receptors found
    target organs (visceral organs) supplied by the postganglionic neuron of the parasympathetic system (cranial and sacral)
  32. Where are nicotinic acetylcholine receptors found
    • between the preganglionic - post ganglionic neurons of both sympathetic and parasympathetic systems
    • between spinal and cranial motor neurons and the somatic (voluntary) motor structures
  33. What two drugs can be used to reverse the effects of carbamates and glycopyrolates on muscarinic receptors
    atronpine or glycopyrolate to block the receptors so they cannon be stimulated
  34. what drug can be used to reverse the effects of cabamates and glycopyrolates on nicotinic receptors
    Pralidoxime (2 - PAM) which separates the orrganophospate and carbamate from teh acetylcholinesterase molecule
  35. What are the largest group of insecticides, this group is unique in that it is very safe...except for cats
  36. Pyrethrins are natural insecticides derived form what flower
  37. Amitraz is classified as what insecticide
  38. What was one of the first effective agents for the treatment of demodectic mange in dogs
  39. Mitaban
  40. What are 2 over the counter products with Amitraz
    • Preventric - tick collar for dogs
    • Taktic - topical liquid/collar for cattle
  41. What type of insecticide, used topically to kill adult fleas (not ticks), is Advantage classified as
    chloronicotinyl nitroguanidine
  42. Frontline
  43. Frontline plus
  44. Frontline has been known to produce a stimulation of sensory nerve endings at the site of application resulting in alopecia called
  45. What are two types of insect growth regulators
    • insect development inhibitors (Lufenuron)
    • Juvenile hormone analogs (Mehtoprene)
  46. Lufenuron interferes with the development of the insets chitin. The flea larvae survives iwth a defective shell, but is unable to hatch. What type of IGR is this considered
    insect development inhibitor
  47. Methoprene is absorbed by the female flea and is incorporated into the flea eggs, resulting in death of the larvae. What type of IGR is this considered
    Juvenile hormone analogs
  48. What are two ways that juvenile hormone analogs kill larvae
    • egg will not develop
    • egg develops but the larvae are dead on hatch
Card Set
Antiparasitic drugs
for drugs yo
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