Generic Name: Ketoprofen

  • What is Ketoprofen?

    Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the signs and symptoms of rheumatoid arthritis (a type of arthritis that involves inflammation of the joints) and osteoarthritis (a type of arthritis that involves the breakdown of cartilage in the joints). It is also used to relieve mild to moderate pain, as well as menstrual pain.

  • What is the most important information I should know about Ketoprofen?

    Ketoprofen may increase your risk of life-threatening heart or circulation problems, including heart attack or stroke, especially with long-term use or if you have heart disease. These may occur without warning signs. Tell your doctor immediately if you experience chest pain, shortness of breath, or weakness.

    You should have frequent check-ups with your doctor if you take ketoprofen regularly. Ulcers or internal bleeding can occur without warning and can be life-threatening. The chance of getting an ulcer or bleeding is greater if you are older; are taking corticosteroid medications or blood thinners; if you smoke or drink alcohol; or if you experience sudden poor health. Tell your doctor immediately if you experience stomach pain, indigestion, or bloody vomit or stools.

    Contact your doctor if you experience any changes in your vision, skin rash or blisters with fever, unexplained weight gain or fluid retention, yellowing of your skin or whites of your eyes, "flu-like" symptoms, difficulty breathing, or swelling of the face or throat while taking ketoprofen.

  • Who should not take Ketoprofen?

    Do not take ketoprofen just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

    Do not take ketoprofen if you are sensitive to or have ever had an allergic reaction to ketoprofen, or if you have had asthma attacks, hives, or other allergic reactions caused by aspirin or other NSAIDs. Make sure your doctor is aware of any drug reactions you have experienced.

  • What should I tell my doctor before I take the first dose of Ketoprofen?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with ketoprofen. Also, talk to your doctor about your complete medical history, especially if you have a history of heart attack, stroke, blood clot, heart disease, congestive heart failure, high blood pressure, a history of stomach ulcers or bleeding, low red blood cells (anemia), bowel problems, diverticulosis (a condition in which pockets form in the large intestine), liver or kidney disease, asthma, nasal polyps (non-cancerous growth in the nose), had life-threatening allergic reactions, if you smoke or drink alcohol, or if you had or plan to have CABG surgery.

  • What is the usual dosage?


    Rheumatoid Arthritis and Osteoarthritis

    Adults: The starting dose is 75 milligrams (mg) three times a day or 50 mg four times a day. The maximum daily dose is 300 mg a day. Your doctor will prescribe the appropriate dose for you based on your condition.

    Mild to Moderate Pain and Menstrual Pain

    Adults: The usual dose is 25-50 mg every 6-8 hours as needed.

  • How should I take Ketoprofen?

    Take ketoprofen exactly as prescribed by your doctor. It should be used at the lowest dose possible for your treatment for the shortest time needed.

    To minimize side effects, your doctor may recommend that you take ketoprofen with food, an antacid, or milk.

    If you are using ketoprofen for arthritis, it should be taken regularly.

  • What should I avoid while taking Ketoprofen?

    Do not use any other over-the-counter cold, allergy, or pain medications without first asking your doctor or pharmacist. Many medications available over the counter contain medicines similar to ketoprofen (such as aspirin, ibuprofen, or naproxen). Do not drink alcohol while taking ketoprofen. Alcohol may increase the risk of stomach bleeding.

  • What are possible food and drug interactions associated with Ketoprofen?

    If ketoprofen is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining ketoprofen with the following: alcohol; aspirin; blood thinners such as warfarin; diuretics (water pills) such as hydrochlorothiazide or furosemide; heart medications known as angiotensin-converting enzyme inhibitors; lithium; methotrexate; and probenecid.

    Do not combine pain relievers without asking your doctor.

  • What are the possible side effects of Ketoprofen?


    Side effects may include: abdominal pain, anorexia, changes in kidney function, constipation, depression, diarrhea, dreams, drowsiness, fluid retention, gas, headache, heartburn, inability to sleep, indigestion, nausea, nervousness, rash, ringing of the ears, signs or symptoms of a urinary tract infection, tiredness, visual disturbances, vomiting

  • Can I receive Ketoprofen if I am pregnant or breastfeeding?

    The effects of ketoprofen during pregnancy and breastfeeding are unknown. Do not use ketoprofen during the last 3 months of your pregnancy. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Ketoprofen?


  • How should I store Ketoprofen?

    Store at room temperature.