Using of Hybrid Nanoantibiotics as Promising Antimicrobial Agent


Nanoparticles are particles with size 1-100 nm, which exhibit different shapes like spherical, triangular, rod, etc. Research on synthesis of nanoparticles is the current area of interest due to the unique visible properties (chemical, physical, optical) of nanoparticles compared with the bulk material. Owing to the wide range of applications offered by nanoparticles in different fields of science and technology, different protocols have been designed for their synthesis. The nanoparticles can be synthesized using the top-down (physical) approach which deals with methods such as thermal decomposition, diffusion, irradiation, arc discharge, and bottom-up (chemical and biological) approach,which involves seeded growth method, polyol synthesis method, electrochemical synthesis, chemical reduction, and biological entities for fabrication of nanoparticles. Different synthesis methods involve the use of different types of chemical, physical, and biological agents to yield nanoparticles of different sizes and shapes. The most often used method for the chemical synthesis of nanoparticles is the chemical reduction method, which deals with the reduction of metal particles to nanoparticles using chemical reducing agents like sodium borohydride or sodium citrate.