Onset of Systemic lupus erythematosus related with Genes

Genes are the constituents of the long chains of DNA that are capable of varying from one person to another. One such variation in a gene on the X chromosome is capable of giving to an exaggerated immune response in men. The only reason why Systemic lupus erythematosus has been found in a lesser frequency in males is that the X chromosome is found in a suppressive mode in males. However, in cases wherein Systemic lupus erythematosus has been discovered in men it was found with much higher level of grievousness.