Reactome: A Curated Pathway Database
Results 1 to 10 of 17
Pathways (9) Reactions (3) Proteins (1) Others (4)
Protein: UniProt:Q09428 ABCC8 (Homo sapiens)
Last changed: 2015-03-12 14:00:50

Pathway: Metabolism (Homo sapiens)

Pathway: Neuronal System (Homo sapiens)

Pathway: Transmembrane transport of small molecules (Homo sapiens)

Pathway: Potassium Channels (Homo sapiens)
Potassium channels are tetrameric ion channels that are widely distributed and are found in all cell types. Potassium channels control resting membrane potential in neurons, contribute to regulation of action potentials in cardiac muscle and help release of insulin form pancreatic beta cells. Broadly K+ channels are classified into voltage gated K+ channels, Hyperpolarization activated cyclic nucleo

Pathway: ABC-family proteins mediated transport (Homo sapiens)
The ATP-binding cassette (ABC) superfamily of active transporters involves a large number of functionally diverse transmembrane proteins. They transport a variety of compounds through membranes against steep concentration gradients at the cost of ATP hydrolysis. These substrates include amino acids, lipids, inorganic ions, peptides, saccharides, peptides for antigen presentation, metals, drugs, and p

Pathway: Integration of energy metabolism (Homo sapiens)
Many hormones that affect individual physiological processes including the regulation of appetite, absorption, transport, and oxidation of foodstuffs influence energy metabolism pathways. While insulin mediates the storage of excess nutrients, glucagon is involved in the mobilization of energy resources in response to low blood glucose levels, principally by stimulating hepatic glucose ou

Pathway: Regulation of insulin secretion (Homo sapiens)

Pathway: ATP sensitive Potassium channels (Homo sapiens)
ATP sensitive K+ channels couple intracellular metabolism with membrane excitability. These channels are inhibited by ATP so are open in low metabolic states and close in high metabolic states, resulting in membrane depolarization triggering responses such as insulin secretion, modulation of vascular smooth muscle and cardioprotection. The channel comprises four Kir6.x subunits and four regulatory sulp

Pathway: Inwardly rectifying K+ channels (Homo sapiens)
Inwardly rectifying K+ channels (Kir channels) show an inward rather than outward (like the voltage gated K+ channels) flow of K+ thereby contributing to maintenance of resting membrane potential and regulation of action potential in excitable tissue. Kir channels are found in a variety of cell types such as cardiac myocytes, neurons, blood cells, osteoblasts, glial cells, epithelial cells, and oocyte

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