Providing patients with information to make more informed care decisions.
Most pregnancies result in the birth of a healthy baby. About 3 out of 100 babies have some type of medical condition, such as a birth defect. Genetic testing during pregnancy can sometimes detect these types of medical conditions before birth; however, it is important to note that the majority of women who undergo genetic testing for their pregnancy will have normal results. 

When to Consider Prenatal Microarray Analysis?

As an expecting mother, it is common to have questions or concerns about the health of your baby. In addition to routine prenatal diagnostic testing, such as a karyotype, CombiMatrix offers CombiSNP™ Microarray testing for Prenatal Diagnosis. Your doctor may offer or recommend microarray testing if:

  • Maternal blood tests (NIPT or serum screening) during pregnancy were abnormal, indicating an increased chance of a medical condition or birth defect
  • One or more fetal anomalies are seen on prenatal ultrasound
  • You had a previous child with a medical condition due to a chromosomal problem
  • You have experienced two or more pregnancy losses
  • You are over 35 years of age

How is Prenatal Microarray Testing Performed?

Microarray analysis requires an amniocentesis or chorionic villus sampling procedure to obtain cells that contain the baby’s chromosomes. Depending on your doctor’s recommendations and the size of the sample received by the laboratory, microarray testing may be performed either prior to or following routine testing, such as karyotyping. If microarray is performed prior to karyotyping on direct amniotic fluid or chorionic villi, test results are typically available within 7-10 days. If karyotyping is performed first, or your sample has to be cultured, results are typically available 7-10 days following the karyotyping results. Your doctor will review the results with you and address any questions you might have.

Prenatal Microarray Literature:

Prenatal Diagnosis
Prenatal Diagnosis - Spanish

Please speak to your primary care provider about microarray.

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