Protein classification resources at the EBI: InterPro




InterPro is the main resource for protein classification at the EBI.

In InterPro, patterns, profiles, fingerprints and HMMs from a number of different databases are brought together into a single searchable resource, offering convenient access to their predictive capabilities without the need to visit the member databases individually (see Figure 18 for an overview of the databases used to construct InterPro).

By combining the different databases and signature types, InterPro capitalises on their individual strengths, producing a powerful tool for the prediction of protein function. InterPro aims to simplify and rationalise protein sequence analysis for the user by combining and organising information in a consistent manner, removing redundancy, and adding extensive annotation and useful links about the signatures and the proteins they match.

Figure 18 An overview of the different databases that are used to construct InterPro.