Meagan E Jones

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Cells growing in culture are subject to mutation, and as mutation is a random event, the number of mutants in a culture will be a random variable. The size of the clone of mutants arising from a single mutational event depends on the timing of the mutation; the earlier the mutation the larger the corresponding clone of mutants. The frequency with which new(More)
In estimating the spontaneous mutation rate, mu, in cultured mammalian cells, the number of mutant cells in several parallel cultures, each a clone from a single cell, is determined. Luria and Delbrück (1943), and subsequently Lea and Coulson (1949), proposed several estimators of mu using data from such experiments. These methods of analysis were(More)
When the spontaneous mutation rate mu in mammalian cell cultures is estimated using Luria-Delbrück fluctuation analysis, many factors contribute to the unreliability of the estimate. Some of these have been documented by Featherstone et al. (1987) and by Kendal and Frost (1988). In particular, the plating efficiencies for mammalian cells are often much less(More)
The use of playback experiments to study humpback whale song was assessed. Singers clearly detected playback song while singing and with other singers in the distance. Singers approached or joined song similar to their own from as far as 800 m but did not do so for a different (foreign) song. In one compound trial, on the playback of different song, the(More)
Dense aggregating fields of P. violaceum and P. pallidum exhibit propagated waves which may be analogous to those seen in Dictyostelium discoideum. As in D. discoideum the wave velocity is determined by an intracellular delay between stimulation and response, rather than by the diffusion coefficient of the acrasin. The frequency of the propagated wave(More)
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