High hemoglobin count occurs most commonly when your body requires an increased oxygen-carrying capacity, usually because:

  1. You smoke
  2. You live at higher altitudes and your red blood cell production naturally increases to compensate for the lower oxygen supply there

High hemoglobin count occurs less commonly because:

  2. You have a bone marrow dysfunction that results in increased production of red blood cells.
  3. You've taken drugs or hormones, most commonly erythropoietin (EPO), that stimulate red blood cell production. You're not likely to get a high hemoglobin count from EPO given to you if you have chronic kidney disease. But EPO doping — getting injections to enhance athletic performance — can cause a high hemoglobin count.

A high hemoglobin count in the absence of any other abnormalities is unlikely to be related to any condition of concern. Specific disorders or other factors that may cause a high hemoglobin count include:

  1. COPD (chronic obstructive pulmonary disease) and other lung diseases
  2. Congenital heart disease in adults
  3. Emphysema
  4. Heart failure
  5. Kidney cancer
  6. Liver cancer
  8. Polycythemia vera
  9. Other types of heart disease
  10. Other types of lung disease
  11. Smoking, which may result in low blood oxygen levels


Jan. 14, 2016