Evolutionary developmental biology

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Evolutionary developmental biology interprets development in the light of evolution and modern genetics. It is called for short 'evo-devo'.


"We can see why characters derived from the embryo should be of equal importance with those derived from the adult, for a natural classification of course includes all ages".[2]

Ernst Haeckel (1866) proposed that "ontogeny recapitulates phylogeny", that is, the development of the embryo of every species (ontogeny) repeats the evolutionary development of that species (phylogeny).[1] Haeckel's concept explained, for example, why humans, and indeed all vertebrates, have gill slits and tails early in embryonic development. His theory has since been largely discredited.

The modern evolutionary synthesis[change | change source]

A renewed interest in the evolution of development came after the modern evolutionary synthesis (roughly 1936 to 1947). The conventional view had been that evo-devo had little influence on the evolutionary synthesis, but the following suggests otherwise.

Gavin de Beer[change | change source]

In Embryos and evolution (1930) Gavin de Beer stressed the importance of heterochrony, and especially paedomorphosis in evolution.[3][4][5]

According to his theories, paedomorphosis (the retention of juvenile features in the adult form) is important in evolution because juvenile tissues are relatively undifferentiated and capable of further evolution, whereas highly specialised tissues are less able to change.

He also conceived the idea of clandestine evolution, which helped to explain the sudden changes in the fossil record which were apparently at odds with Darwin's gradualist theory of evolution.

If a novelty were to evolve gradually in an animal's juvenile form, then its development might not appear in the fossil record at all, but if the species were then to undergo neoteny, in which sexual maturity is reached while in a juvenile form, then the feature would appear suddenly in the fossil record, despite having evolved gradually.

"In a series of remarkable books that established the synthetic theory of evolution, Gavin de Beer's Embryology and evolution was the first and the shortest (1930; expanded and retitled Embryos and ancestors, 1940; 3rd ed 1958). In 116 pages de Beer brought embryology into the developing orthodoxy... for more than forty years, this book has dominated English thought on the relationship between ontogeny and phylogeny". Stephen Gould [6]p221

Stephen Jay Gould called this approach to explaining evolution as terminal addition; as if every evolutionary advance was added as new stage by reducing the duration of the older stages. The idea was based on observations of neoteny.[7] This was extended by the more general idea of heterochrony (changes in timing of development) as a mechanism for evolutionary change.[6]

Neoteny and Man[change | change source]

It has often been suggested that the human species is, at least to some extent, an example of neoteny. These features of adult humans are different from those of adult great apes, but more similar to those of juvenile apes:

These are some of the neotenous traits in humans: flattened face,[8] broadened face,[6] large brain,[8] hairless body,[8] hairless face,[9] small nose,[9] reduction of brow ridge,[8] small teeth,[8] small upper jaw (maxilla),[8] small lower jaw (mandible),[8] thinness of skull bones,[6] limbs proportionately short compared to torso length,[6] longer leg than arm length,[10] larger eyes,[11] and upright stance.[12][13]

Even more significant is the way that humans continue to learn and play into adult life, whereas in apes (and other mammals) this kind of behaviour is usually shown only in juveniles. This strongly suggest that our brain activities are, at least in this respect, more similar to juvenile apes than to adult apes.

Genetics and evo-devo[change | change source]

E.B. Lewis[change | change source]

Modern interest in evo-devo springs from clear proof that development is closely controlled by special genetic systems involving hox genes.[14][15][16]



Each of the genes contains a homeobox,[21] a remarkably conserved DNA sequence,[22] which is similar in many widely different animals. This suggests the complex itself arose by gene duplication.[23][24][15] In his Nobel lecture, Lewis said "Ultimately, comparisons of the [control complexes] throughout the animal kingdom should provide a picture of how the organisms, as well as the [control genes] have evolved".

In 2000, a special section of the Proceedings of the National Academy of Sciences (PNAS) was devoted to evo-devo,[25] and an entire 2005 issue of the Journal of Experimental Zoology Part B: Molecular and Developmental Evolution was devoted to the key evo-devo topics of evolutionary innovation and morphological novelty.[26]

Further reading[change | change source]

  • Carroll, Sean B. 2005. Endless forms most beautiful: the new science of evo devo. New York: Norton. ISBN 0-393-06016-0

References[change | change source]

  1. 1.0 1.1 Bowler 2003, pp. 170, 190–191
  3. de Beer, Gavin 1930. Embryology and evolution. Oxford University Press. (later editions were titled Embryos and ancestors)
  4. Brigandt I. 2006. Homology and heterochrony: the evolutionary embryologist Gavin Rylands de Beer (1899-1972)
  5. Journal of Experimental Zoology (Molecular and Developmental Evolution) 306B:317-328. preprint
  6. 6.0 6.1 6.2 6.3 6.4 Gould S.J. 1977. Ontogeny and phylogeny. Cambridge, Massachusetts: Belknap Press. ISBN 0-674-63940-5
  7. Ridley, Mark (2003). Evolution. Wiley-Blackwell. ISBN 978-1-4051-0345-9. http://www.blackwellpublishing.com/ridley/.
  8. 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Montagu A. 1989. Growing young. Bergin & Garvey: CT.
  9. 9.0 9.1 Jean-Baptiste de Panafieu P. 2007. Evolution. Seven Stories Press.
  10. Maynard Smith J. 1958. The theory of evolution. Cambridge University Press.
  11. http://zidbits.com/2011/06/why-do-men-find-women-with-larger-eyes-attractive/
  12. Hetherington R. 2010. The climate connection: climate change and modern human evolution. Cambridge University Press.
  13. Henke W. 2007. Handbook of paleoanthropology, Volume 1. Springer, N.Y.
  15. 15.0 15.1 Gehring W. 1999. Master control systems in development and evolution: the homeobox story. Yale.
  18. Lawrence P. 1992. The making of a fly. Blackwell, Oxford.
  21. The genes are called homeotic genes; both homeosis and homeobox derive from the idea of homeostasis or regulation. These are regulatory genes.
  22. Here "conserved" means it has changed little over the last 500 million years, or longer.
  25. Goodman CS and Coughlin BS (Eds). (2000). "Special feature: the evolution of evo-devo biology". Proceedings of the National Academy of Sciences 97 (9): 4424–4456. doi:10.1073/pnas.97.9.4424. PMC 18255. PMID 10781035. http://www.pnas.org/cgi/content/full/97/9/4424.
  26. Müller G.B. and Newman S.A. eds (2005). "Special issue: Evolutionary innovation and morphological novelty". Journal of Exp. Zool. Part B: Molecular and Developmental Evolution 304B: 485–631. http://www3.interscience.wiley.com/cgi-bin/jissue/112149101.