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Priapism is a prolonged and painful erection that lasts for an abnormally long period (more than three hours) and occurs without sexual stimulation and after ejaculation.

Priaprism can affect males of any age and can occur spontaneously or as a result of an obvious medical explanation such as drug or alcohol abuse. Left untreated the condition may permanently damage the muscle and erectile tissue of the penis leading to erectile dysfunction (impotency) and penile disfigurement.

When a normal erection occurs, blood flows into the penis and drains out of the penis (usually after orgasm), without any discomfort. With priapism, blood that fills the penis is unable to be drained and becomes trapped. Because there isn't much room for the blood to move in the penis, the blood becomes stagnant, loses oxygen and the blood cells become stiff, making drainage even more difficult.