Pyruvate for Weight Control

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Why Use


Why Do Dieters Use It?*

Some dieters say that pyruvate helps them lose inches and also boosts metabolism and improves energy levels.

What Do the Advocates Say?*




Dosage & Side Effects


How Much Is Usually Taken by Dieters?

Pyruvate, a compound that occurs naturally in the body, might aid weight-loss efforts.1 A controlled trial found that pyruvate supplements (22 to 44 grams per day) enhanced weight loss and resulted in a greater reduction of body fat in overweight adults consuming a low-fat diet.2 Three controlled trials combining 6 to 10 grams per day of pyruvate with an exercise program reported greater effects on weight loss and body fat than that seen with a placebo plus the exercise program.3 , 4 , 5 Animal studies suggest that pyruvate supplementation leads to weight loss by increasing the resting metabolic rate.6

Side Effects

High intakes of pyruvate can trigger gastrointestinal upset, such as gas, bloating, and diarrhea. One preliminary study in exercising women found 10 grams per day of pyruvate reduced blood levels of HDL (the “good” cholesterol) after one month.7

Interactions with Supplements, Foods, & Other Compounds


Interactions with Medicines


More Resources


Where to Find It

Pyruvate is formed in the body as a byproduct of the normal metabolism of carbohydrates and protein and is present in several foods, including red apples, cheese, dark beer, and red wine. Dietary supplements of pyruvate are also available.

