Skin and Skin Structure Infections (SSSI)

Skin and skin structure infections (SSSI) encompass a range of bacterial-related illnesses that can manifest in a variety of symptoms. The extent of the disease can range from mild to severe. Common skin structure infections include post-surgical wound infections, carbuncles, and traumatic wound infections. The organisms causing SSSI are typically Gram-positive bacterial pathogens, such as Staphylococcus aureus and Streptococcus pyogenes. Aside from the general complications associated with skin infections, such as the swelling and discharge common with carbunculosis, other more serious symptoms can occur. For example, streptococcal infections of cutaneous and soft tissue can range from localized impetigo to invasive fasciitis with associated toxic shock that can rapidly lead to death. The market is set to grow at a CAGR of 1.0%, from $ 2.4bn in 2011 to $ 2.6bn in 2019. The evolution of new Staphylococcus aureus strains (VISA, VRSA) provides scope for the high activity of OxAG against these bacterial strains.