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Microcystic adnexal carcinoma

Other Names for this Disease
  • MAC


What is microcystic adnexal carcinoma?

What are the symptoms of microcystic adnexal carcinoma?

What is microcystic adnexal carcinoma?

Microcystic adnexal carcinoma is a rare tumor of the skin that most often develops in the head and neck region, particularly in the middle of the face, though it may occur in the skin of other parts of the body as well.[1]  The average age of diagnosis is 56.[2]  This tumor is often first noticed as a bump or yellowish spot in the skin.  Though microcystic adnexal carcinomas frequently grow into and disturb nearby tissues and is therefore considered an invasive cancer, this type of tumor rarely spreads to more distant parts of the body (metastasizes).[1] The main treatment for microcystic adnexal carcinoma is Mohs micrographic surgery, which is thought to improve the chances that all of the tumor cells are removed during surgery.[2][1]
Last updated: 7/18/2012

What are the symptoms of microcystic adnexal carcinoma?

Microcystic adnexal carcinoma appears as a smooth bump or patch that is slightly raised from the surrounding skin.  It may be flesh-colored or yellowish, and it increases in size over time.  A microcystic adnexal carcinoma may grow into nerves nearby, which can cause discomfort, numbness, tingling (paresthesia), burning, or itching.[1]
Last updated: 7/18/2012

  1. Wetter R, Goldstein GD. Microcystic adnexal carcinoma: a diagnostic and therapeutic challenge. Dermatologic Therapy. 2008; 21:452-458. Accessed 11/4/2011.
  2. Snow S, Madjar DD, Hardy S, Bentz M, Lucarelli MJ, Bechard R, Aughenbaugh W, McFadden T, Sharata H, Dudley C, Landeck A. Microcystic adnexal carcinoma: report of 13 cases and review of the literature. Dermatologic Surgery. 2001; 27:401-408. Accessed 11/4/2011.