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  • The Pin Index Safety System, or PISS, is a safety system that uses geometric features on the yoke to ensure that pneumatic connections between a gas cylinder and a machine that uses pressurized gases are not connected to the wrong gas yoke. This system can be seen on an anesthesia machine. Each gas cylinder has a pin configuration to fit its respective gas yoke. Refer to the figure on the right; units are in millimeters. O2: 2-5 N2O: 3-5 Air: 1-5 CO2: 1-6 He: No pin Mixture of O2 / He: 2-4 Mixture of O2 / N2O: 7 Wikipedia