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Transposition of the Great Vessels Lawsuit

Studies have found that children born to mothers who take certain prescription medications during pregnancy have an increased risk of a severe birth defect called transposition of the great vessels, or TGV. 

What is Transposition of the Great Vessels?

TGV is a cyanotic heart defect in which the two major vessels that carry blood away from the heart — the aorta and the pulmonary artery — are switched and in the opposite position. In someone suffering from this condition, blood goes to the lungs, picks up oxygen, and then goes right back to the lungs without ever going to the body. Inversely, blood from the body returns to the heart and goes back to the body without ever picking up oxygen in the lungs. This results in decreased oxygen in the blood that is pumped from the heart to the rest of the body, which leads to symptoms including blueness of the skin, clubbing of the fingers or toes, poor feeding, and / or shortness of breath.

British Medical Journal Study on Antidepressant Birth Defects

According to a recent British Medical Journal study, pregnant women should weigh their emotional health against the risks of taking antidepressants during pregnancy, which could lead to life-threatening birth defects. The most significant problems uncovered by the study were congenital heart defects like TGV, in which babies are born with problems in the upper or lower chambers of their hearts.

Dangerous Drugs Linked to TGV

The following medications have been associated with the development of transposition of the great vessels in babies born to mothers who take them during pregnancy:

Outlook (Prognosis)

In most cases, the affected individual’s symptoms will improve after surgery to correct the defect. Sadly, if corrective surgery is not performed, the life expectancy is only a few months. Most infants who undergo arterial switch do not have symptoms after surgery and live normal lives.

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