Pronunciation: ox AL i PLA tin

Brand: Eloxatin

Eloxatin 200 mg

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What is the most important information I should know about oxaliplatin?

Oxaliplatin can cause a severe or life-threatening allergic reaction. Get emergency medical help if you have: hives, itching, sweating; chest pain, warmth or redness in your face, feeling light-headed; sudden cough, difficult breathing; swelling of your face, lips, tongue, or throat.

What is oxaliplatin?




What should I discuss with my healthcare provider before receiving oxaliplatin?

You should not be treated with this medicine if you have ever had an allergic reaction to oxaliplatin or similar medications such as carboplatin (Paraplatin) or cisplatin (Platinol).

To make sure oxaliplatin is safe for you, tell your doctor if you have:

  • kidney disease;
  • liver disease;
  • heart disease, heart rhythm disorder;
  • a personal or family history of long QT syndrome;
  • high blood pressure;
  • asthma or other breathing disorder;
  • a nerve problem; or
  • if you are using a blood thinner such as warfarin (Coumadin, Jantoven).

Do not use oxaliplatin if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.


How is oxaliplatin given?

Oxaliplatin is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Oxaliplatin must be given slowly, and the infusion can take at least 2 hours to complete.

Oxaliplatin is given once every 2 weeks. Your doctor will determine how long to treat you with this medicine.

You may be given medication to prevent nausea or vomiting while you are receiving oxaliplatin.


  • do not inhale deeply when you are exposed to cold air;
  • cover your skin, head, and face when you are outside in cold temperatures;
  • wear gloves when handling cold objects or refrigerated foods;
  • do not run an air conditioner at very cool temperature in your home or car (even during hot weather);
  • do not drink cold drinks or use ice cubes in drinks;
  • do not put ice packs on your body.

Chemotherapy often causes nausea or mouth sores. Do not eat ice chips to ease these discomforts because you will be more sensitive to cold. Talk to your doctor about other ways to treat nausea or mouth sores. You may be given other medications to prevent nausea or vomiting while you are receiving oxaliplatin.



What happens if I miss a dose?

Contact your doctor if you miss an appointment for your oxaliplatin injection.

What happens if I overdose?


What should I avoid while receiving oxaliplatin?

Avoid cold temperatures and cold objects, including ice, cold drinks, and skin exposure to cold temperatures.




What are the possible side effects of oxaliplatin?



Call your doctor at once if you have:

  • increased sensitivity to cold temperatures and cold objects;
  • severe or ongoing diarrhea or vomiting;
  • confusion, change in mental status, vision problems, seizure (convulsions);
  • pain or burning when you urinate;
  • easy bruising, unusual bleeding (nosebleeds, bleeding gums);
  • heart problems --headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
  • muscle problems --unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine;
  • nerve problems --jaw or chest tightness, eye pain, strange feeling in your tongue, problems with speech or swallowing; or
  • signs of infection --fever, chills, sore throat, mouth and throat ulcers, pain when swallowing, cough with mucus.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • numbness or tingling;
  • infections, unusual bleeding;
  • abnormal liver function tests;
  • mouth sores; or
  • feeling tired.


What other drugs will affect oxaliplatin?


Where can I get more information?

Your doctor or pharmacist can provide more information about oxaliplatin.



Copyright 1996-2015 Cerner Multum, Inc. Version: 9.05. Revision date: 1/4/2016.
