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When undergoing fertility treatments you may be prescribed fertility drugs to help with the successful implantation of a fertilized egg.

Progesterone (brand names include Provera, Endometrin, Crinone, Prometrium or Cyclogest) is one of the primary female reproductive hormones, which is produced immediately after ovulation and helps build up and ready the uterine lining for implantation of a fertilized egg. Physicians may prescribe progesterone supplements if your corpus luteum does not produce enough progesterone.

There are many different types of progesterone therapy.

  • Synthetic progesterone, such as Provera, is administered orally or through injection and is typically used to help trigger menstruation. It is not considered safe to take during pregnancy and may increase the risk of birth defects.
  • Oral progesterone, such as Prometrium, is a natural form of the hormone used to help supplement the luteal phase during fertility treatments such as intrauterine insemination (IUI).
  • Progesterone suppositories, such as Endometrin and Cyclogest, are made of natural progesterone and are inserted into the vagina.
  • Bioadhesive gels, such as Crinone, often used during IUI and in vitro fertilization (IVF), contain a natural form of progesterone and are inserted into the vagina using a tampon-like applicator.
  • Injectable progesterone is often referred to as progesterone in oil. Historically it was viewed as the most effective administration, but newer types of progesterone therapy are gaining popularity for their efficacy, ease and comfort.

The cost of progesterone therapy varies according to what type is used. Six applications of progesterone gel costs around $80.


Comments (2)

Can I take provera after using clomid in fertility treatment? To prepare the uterine wall

Hi Mizaza, Your fertility doctor or OB-GYN can best advise you on using Provera after a Clomid cycle. Best of luck! Kim