US Pharm. 2014;39(3):61.

Liverpool, England—More than half of patients taking antidepressants may experience psychological side effects, according to University of Liverpool researchers. In a survey of 1,829 people who had been prescribed antidepressants in the past 5 years, participants chose from a list of 20 adverse effects to describe how they had felt while taking the medication. Participants aged 18 to 25 years reported sexual difficulties (62%), feeling emotionally numb (60%), and suicidal feelings (>50%); in the broader sample, participants reported not feeling like themselves (53%), reduction in positive feelings (42%), and caring less about others (39%). The psychological and interpersonal effects of antidepressants have been less widely studied than the physiological side effects.

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