Fusel alcohol

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Fusel alcohols or fuselol, also sometimes called fusel oils in Europe, are a mixture of several alcohols (chiefly amyl alcohol) produced as a by-product of alcoholic fermentation.[1] The word fusel is German for "bad liquor".[2]

Whether fusel alcohol contributes or not to hangover symptoms is a matter of scientific debate. A Japanese study in 2003 concluded, "The fusel oil in whisky had no effect on the ethanol-induced emetic response" in Suncus murinus. Additionally, consumption of fusel oils with ethanol suppressed subjects' subsequent taste aversion to alcohol, which suggested subjects' hangover symptoms were lessened, according to the journal.[3]


Fusel oil and fusel oil acetates are needed by the lacquer industry for high boiling lacquer solvents.[4]


Hazardous alcohols[edit]

Alcohol faults[edit]

See also: wine fault

Aroma alcohols[edit]

Excessive concentrations of some alcohols other than ethanol may cause off-flavors, sometimes described as "spicy", "hot", or "solvent-like". Some beverages, such as rum, whisky (especially Bourbon), incompletely rectified vodka (e.g. Siwucha), and traditional ales and ciders, are expected to have relatively high concentrations of non-hazardous alcohols as part of their flavor profile. However, in other beverages, such as Korn, vodka, and lagers, the presence of alcohols other than ethanol is considered a fault.[8]

The compounds involved are chiefly:[9]

During distillation, fusel alcohols are concentrated in the feints or "tails" at the end of the distillation run. They have an oily consistency, which is noticeable to the distiller, hence the other name "fusel oil". If desired, these heavier alcohols can be almost completely separated in a reflux still. Freeze distillation, on the other hand, does not remove fusel alcohols.[citation needed]

Fusel alcohols are formed when fermentation occurs:[citation needed]

  • at higher temperatures
  • at lower pH
  • when yeast activity is limited by low nitrogen content

See also[edit]


  1. ^ http://oxforddictionaries.com/definition/english/fusel%2Boil
  2. ^ Hazelwood, Lucie A.; Daran, Jean-Marc; van Maris, Antonius J. A.; Pronk, Jack T.; Dickinson, J. Richard (2008). "The Ehrlich pathway for fusel alcohol production: a century of research on Saccharomyces cerevisiae metabolism". Appl. Environ. Microbiol. 74 (8): 2259–66. doi:10.1128/AEM.02625-07. PMC 2293160Freely accessible. PMID 18281432. 
  3. ^ Hori H, Fujii W, Hatanaka Y, Suwa Y (Aug 27, 2003). "Effects of fusel oil on animal hangover models.". Alcohol Clin Exp Res. 27 (8 Suppl): 37S–41S. doi:10.1097/01.ALC.0000078828.49740.48. PMID 12960505. 
  4. ^ AMYL COMPOUNDS FROM PENTANE Richard L. Kenyon, Gordon C. Inskeep, Leslie Gillette, and J. Frank Price Industrial & Engineering Chemistry 1950 42 (12), 2388-2401 doi:10.1021/ie50492a004
  5. ^ http://chem.sis.nlm.nih.gov/chemidplus/
  7. ^ Mańkowski W, Klimaszyk D, Krupiński B (2000). "How to differentiate acute isopropanol poisoning from ethanol intoxication? -- a case report". Przeglad lekarski. 57 (10): 588–90. PMID 11199895. 
  8. ^ Aroma of Beer, Wine and Distilled Alcoholic Beverages
  9. ^ MERCK INDEX (10th ed.). 1983. 

External links[edit]