Cysteinyl-tRNA synthetase (CARS) is a gene that encodes a transcription factor protein that functions as a regulator of target genes that modulate biological processes such as cell growth, angiogenesis, migration, proliferation, and differentiation. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015
