10 Weirdest Diseases

Weird Diseases

We tend to trust that doctors are on top of this whole “getting sick” phenomenon — when we visit the hospital, we know that someone is going to be able to tell us what’s wrong with us and how to fix it. But then there are some particularly unusual diseases out there that have medical professionals baffled. Get ready for the weird.

1.  Elephantiasis A.K.A “grossly enlarged members.”



2. Progeria A.K.A “the 80-Year-Old Children.”



3. Werewolf Syndrome A.K.A “the wolf people.”

Werewolf Syndrome


4. Blue Skin Disorder A.K.A “the blue people.”

Blue Skin Disorder

A large family simply known as the “blue people” lived in the hills around Troublesome Creek in Kentucky until the 1960s. They were the blue Fugates. Most of them lived past the age of 80, with no serious illness – just blue skin. The trait was passed on from generation to generation. People with this condition have blue, plum, indigo or almost purple skin.

5. Pica A.K.A “the urge to eat non-food substances.”



6. Vampire Disease A.K.A “pain from the sun.”

Vampire Disease


7. Alice in Wonderland Syndrome A.K.A “Everything is distorted.”

Alice in Wonderland Syndrome

Alice in Wonderland Syndrome (AIWS), or micropsia, is a disorienting neurological condition which affects human visual perception. Subjects perceive humans, parts of humans, animals, and inanimate objects as substantially smaller than in reality. Generally, the object perceived appears far away or extremely close at the same time. For example, a family pet, such as a dog, may appear the size of a mouse, or a normal car may look shrunk to scale. This leads to another name for the condition, Lilliput sight or Lilliputian hallucinations, named after the small people in Jonathan Swift’s Gulliver’s Travels. The condition is in terms of perception only; the mechanics of the eye are not affected, only the brain’s interpretation of information passed from the eyes.

8. Blaschko’s lines A.K.A “strange stripes all over the body.”

Blaschko's lines

Blaschko’s lines are an extremely rare and unexplained phenomenon of human anatomy first presented in 1901 by German dermatologist Alfred Blaschko. Neither a specific disease nor a predictable symptom of a disease, Blaschko’s lines are an invisible pattern built into human DNA. Many inherited and acquired diseases of the skin or mucosa manifest themselves according to these patterns, creating the visual appearance of stripes. The cause of the stripes is thought to result from mosaicism; they do not correspond to nervous, muscular, or lymphatic systems. What makes them more remarkable is that they correspond quite closely from patient to patient, usually forming a “V” shape over the spine and “S” shapes over the chest, stomach, and sides.

9. Walking Corpse Syndrome A.K.A “The Walking Dead.”

Walking Dead


10. Jumping Frenchman Disorder A.K.A “weird reflexes.”

Jumping Frenchman Disorder

The main characteristic is that patients are extremely startled by an unexpected noise or sight. It’s not just twitching when someone sneaks up behind you. Patients with this disorder flail their arms, cry out and repeat words. First identified in some of Maine’s lumberjacks of French-Canadian origin, the odd reflex has been identified in other parts of the world, too.


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