An element with atomic symbol O, atomic number 8, and atomic weight 16. It is the most abundant element on earth and essential for respiration.
Also Known As:
Networked: 52482 relevant articles (2117 outcomes, 4974 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Zhang, John H: 55 articles (01/2016 - 02/2002)
2. Ratcliffe, Peter J: 48 articles (06/2015 - 01/2002)
3. Cheung, Po-Yin: 45 articles (02/2015 - 08/2004)
4. Johnson, Randall S: 39 articles (08/2015 - 04/2002)
5. Gassmann, Max: 39 articles (01/2015 - 05/2002)
6. Simon, M Celeste: 37 articles (07/2015 - 01/2003)
7. Semenza, Gregg L: 33 articles (09/2015 - 01/2002)
8. Giaccia, Amato J: 33 articles (06/2015 - 03/2002)
9. Ince, Can: 32 articles (08/2015 - 08/2002)
10. Fandrey, Joachim: 30 articles (12/2015 - 10/2002)

Related Diseases

1. Anoxia (Hypoxia)
07/01/2014 - "Most elk became hypoxemic regardless of BAM dosage, but hypoxemia tended to be most severe in the high-BAM group; regardless of BAM dosage, oxygen supplementation improved the percentage of oxygen saturation and stabilized the vital rates. "
01/01/2013 - "After cold acclimation, susceptibility to hypoxia was not significantly different between the groups, while HCVR significantly increased in Groups 1 and 3, HVR significantly increased in Group 3 and HCVR, HVR did not change in Group 2. Short-term cold exposures caused an increase in functional reserves and improved oxygen supply of tissues in Group 1. Cold exposure hypoxia has caused energy loss in Group 3. Group 2 showed the most appropriate energy conservation reaction mode to cold exposures. "
11/01/2009 - "We found that (1) in contrast to oxygen partial pressure in blood (P(a)O(2)), the baseline value of P(t)O(2) in summer euthermic AGS is significantly higher than in rats; (2) both P(t)O(2) and P(a)O(2) are dramatically reduced by inspired 8% O(2) in AGS and rats, but AGS have a greater capacity in P(t)O(2) to cope with environmental hypoxia; (3) metabolic rate before, during, and after hypoxic exposure is consistently lower in AGS than in rats; (4) the respiratory responding patterns to hypoxia in the two species differ in that f(R) decreases in AGS but increases in rats. "
09/13/2004 - "Acute hypoxia reduced the median oxygen partial pressure (pO(2)) dramatically (1 vs 10 mmHg in controls), whereas in chronically hypoxic tumours the pO(2) was significantly improved (median pO(2)=4 mmHg), however not reaching the control level. "
07/04/1977 - "Portacaval transposition and end-to-side shunt led to a striking oxygen deficit of the liver tissue with no incidence of compensation by the hepatic artery; Oxygen supply was improved considerably by a side-to-side shunt and tissue hypoxia could be prevented by a mesenterico-caval shunt and splenocaval shunt. "
2. Chronic Obstructive Pulmonary Disease (COPD)
3. Neoplasms (Cancer)
08/01/2011 - "As tumor pO2 approaches normal tissue levels, the therapeutic effect is improved so that the normal tissue absorbed doses can be decreased by more than 95%, while retaining TCP, in the most favorable scenario and by up to about 80% with oxygen levels previously achieved in vivo, when the least favourable oxygenation case is used as starting point. "
05/01/1992 - "Krogh cylinder models, which incorporate these data for perivascular oxygen tension, along with morphometric data obtained from the same tumor model suggest that hypoxic regions will exist between tumor vessels in the tumor center unless O2 consumption rates are well below 0.6 ml/100 g/min. The low perivascular measurements observed near the tumor center combined with the theoretical considerations suggest, for this model at least, that tissue oxygenation may best be improved by increasing red cell velocity and input pO2 and reducing oxygen consumption. "
11/01/2010 - "Hyperbaric oxygen (HBO(2)) may be beneficial in the treatment of cancer. "
03/15/2007 - "Although the tumors did not respond to oxygen inhalation, each tumor had a different pO(2), and there was a clear trend between level of oxygenation at time of irradiation and tumor growth delay, with considerably better outcome when mean pO(2) > 10 mm Hg. The comparatively small baseline hypoxic fraction in the group of small tumors was virtually eliminated by breathing oxygen, and the growth rate was significantly reduced for tumors on rats breathing oxygen during irradiation. "
03/15/2007 - "Large tumors (>3.0 cm(3)) exhibited significantly greater hypoxic fractions and lower mean partial pressure of oxygen (pO(2)) than their smaller counterparts (<1.5 cm(3)). "
4. Ischemia
5. Apnea

Related Drugs and Biologics

1. Glucose (Dextrose)
2. Free Radicals
3. Hemoglobins (Hemoglobin)
4. Carbon Dioxide
5. Lactic Acid
6. Nitrogen
7. Nitrous Oxide (Laughing Gas)
8. Carbon Monoxide
9. Superoxide Dismutase
10. Helium

Related Therapies and Procedures

1. Resuscitation
2. Catheters
3. Radiotherapy
4. Drug Therapy (Chemotherapy)
5. Mechanical Ventilators (Ventilator)