Q: About Myoglobin


(P-16) A characteristic of Myoglobin is that:


a)     the Hem is located in a hydrophilic environment


b)     it has primary, secondary, tertiary and quaternary structure.


c)      the iron in the Hem group is in Ferrous state


d)     it shows allosteric regulation


e)     it has four peptide chains.




Q: About the structure of a membrane associated peptide




a)     Ala-Glu-Phe-Arg


b)     Val-Val-Ile-Ala


c)      Asp-Ser-Gly-Tyr


d)     Lys-Val-His-His-Gln


e)     Asp-Val-Gly-Ser



Q: About alpha-Helix structure

Biochemistry Question P-14


Side view of an alpha-helix

Side view of an alpha-helix






This amino acid has a profound effect in the secondary structure of proteins, because when present in the amino acid sequence, it disrupts the a-helix structure:


a)     Alanine


b)     Glycine


c)      Proline


d)     Serine


e)     tryptophan


(The answer in this post)


Top view of an alpha-helix

Top view of an alpha-helix


Extended Match Question about Protein Structure.

It is possible to distinguish different structural levels in the structure of proteins:


a)      Primary Structure


b)      Secondary Structure


c)      Suprasecondary structure


d)     Tertiary Structure


e)      Quaternary Structure



(P-09) This structural level refers to the non covalent association of discrete polypeptide subunits into a multi subunit protein. (Not all proteins have this structural level)


Answer: ___


(P-10) It can be defined as the sequence of amino acids in a polypeptide chain, read from the amino terminal amino acid to the carboxyl terminal amino acid.


Answer: ___


(P-11) This structural level is not affected during the denaturation of  proteins.




(P-12) In Sickle Cell anemia, the amino acid glutamic acid, in the position 6 of the beta chains of Hemoglobin is changed by valine. This disorder is an example of an alteration in this structural level




(P-13) Pr P c (normal protein) and  Pr PSc (abnormal) Prions proteins are very similar proteins.  Pr PSc, related with Creudtzfel-Jacob Disease, fatal insomnia and other human and animal diseases (as mad cow disease), can induce changes in the  structure of Normal Pr Pc protein.  One striking difference between both proteins, that share the same amino acid sequence, is the fact that Pr PSc shows high Beta strand content and low alpha-helix content, while  Pr Pc shows high alpha-helix content and low beta strand content.  Beta strand and alpha helix are types of  this structural level


Answer: ___



Q: About Protein Electrophoresis


Choose the correct electrical  migration of the proteins A,B,C and D in an electric field, knowing that the buffer solution in which are diluted the proteins has a pH of 6,4 and the isoelectric points of the proteins are:


 A = 5.2;  B = 6.4; C = 7.0; D = 9.2


a)     A will migrate to the positive pole, B will not migrate and C and D will migrate to the negative pole.


b)     A will migrate to the negative pole, B will not migrate and C and D will migrate to the positive pole.


c)      A and B will migrate to the negative pole and C and D will migrate to the positive pole


d)     A and B will migrate to the positive pole and C and D will migrate to the negative pole


e)     A will migrate to the negative pole, B and C will not migrate and D will migrate to the positive pole.


Q: About Collagen Synthesis

Question about Proteins P-07







a)     Ascorbic acid


b)     Citric Acid


c)      Folic Acid


d)     Lipoic acid


e)     Panthotenic acid


About Protein Classification


From Ethan Hein in Flickr

 Helices in a protein


Q: A protein X is formed by two chains with 80 amino acids in one chain and 58 in the other. These two chains are linked by disulfide bonds and all the essential amino acids are present in the structure, but not all the non-essential amino acids.  With this information, we can say that this protein is:


a) a globular protein


b) a fibrous protein


c) a conjugated protein


d) an incomplete protein


e) a complete protein


f) a hormone


g) an enzyme