Nonsteroid antienflamatuar

The skin is the body's largest organ. Since it functions to protect us from pathogens and water loss, skin is affected by numerous factors, including what we eat and consume and what type of elements we're exposed to. The most common cause of red skin is rosacea, a chronic skin condition that can be triggered by many things, such as exposure to heat, sun, certain foods or alcohol. Skin can also become red due to symptoms of psoriasis, eczema, or from overexposure to sun or dry weather. Use the following treatments to solve a host of red skin problems.

A number of arguments counted against the COX-3 hypothesis: COX-2-selective inhibitors react weakly with the COX-3 enzymatic site, because the site is identical to that in COX-1, but they are as good at reducing fever as older NSAIDs. The fever response has also been clearly associated with a rapid induction of COX-2 expression and an associated increase in prostaglandin E2 production, with no role for COX-1 or a COX-1 gene product (., COX-3). Finally, the sites of COX-3 expression do not appear to fit in well with those sites associated with fever, and the protein should be present within the hypothalamus rather than the cerebral cortex . All these considerations appeared to argue against COX-3 being the site of the antipyretic actions of NSAIDs and COX-2-selective agents. However, the results could be read as showing that paracetamol acts at a different site than the other NSAIDs and that more than one COX isoform contribute to the fever response.

Nonsteroid antienflamatuar

nonsteroid antienflamatuar


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