Kidney Diseases (Kidney Disease)

Pathological processes of the KIDNEY or its component tissues.
Also Known As:
Kidney Disease; Disease, Kidney; Diseases, Kidney
Networked: 13970 relevant articles (626 outcomes, 1932 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Anemia
2. Hypertension (High Blood Pressure)
3. Proteinuria
4. Secondary Hyperparathyroidism
5. Chronic Kidney Failure (Chronic Renal Failure)


1. Levey, Andrew S: 73 articles (08/2015 - 11/2002)
2. Kalantar-Zadeh, Kamyar: 71 articles (08/2015 - 09/2004)
3. Stenvinkel, Peter: 64 articles (01/2016 - 10/2003)
4. Coresh, Josef: 64 articles (06/2015 - 01/2003)
5. Locatelli, Francesco: 58 articles (01/2016 - 03/2004)
6. Shlipak, Michael G: 56 articles (11/2015 - 03/2005)
7. Kovesdy, Csaba P: 55 articles (08/2015 - 04/2006)
8. Lindholm, Bengt: 54 articles (01/2016 - 10/2003)
9. Sarnak, Mark J: 49 articles (11/2015 - 11/2002)
10. Greene, Tom: 49 articles (07/2015 - 11/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Kidney Diseases:
1. CreatinineIBA
03/01/2013 - "Laboratories in African should commence routine reporting of eGFR for a number of reasons; 1. The sensitivity of serum creatinine (Scr) in identifying CKD is low.2. In Nigeria, a representative country; screening for Chronic Kidney Disease (CKD) is hardly considered in the routine practice of the primary and secondary care medical officers.3 Studies have shown that routine reporting of eGFR improved the documentation and identification of CKD by almost 50%.4 There is the possibility of reversing CKD if picked earlier.5. The high cost of treating CKD patients in advanced stages and the low per capital income status of the populace in Sub-Saharan Africa.6. Poor health infrastructure to manage advanced CKD patients in the continent.7. Several studies, now show lack of awareness of CKD among non-nephrologists that is related, at least in part, to difficulty in interpreting serum creatinine concentrations (the reciprocal, non-linear relationship between GFR and serum creatinine).8 Mathematical estimates of GFR [ as in eGFR] that incorporate creatinine concentration, as well as factors affecting creatinine production rates, such as size, gender, age and ethnic background, are more sensitive to changes in renal function than serum creatinine value alone.9 Recent guidelines define "action plans" for CKD according to the GFR, including referral to nephrologists at GFRs<30 mL.min(-1).(1.73 m2)."
01/01/2004 - "Regardless of the choice between an ACE or ARB, however, post hoc analysis of clinical trials [21,47] and observational data clearly indicate that patients with chronic kidney disease, even if considered mild (ie, serum creatinine greater than or equal to 1.4 mg/dL) are at significantly greater risk of cardiovascular morbidity and mortality compared with those with better kidney function. "
01/01/2015 - "Modified Cut-Off Value of the Urine Protein-To-Creatinine Ratio Is Helpful for Identifying Patients at High Risk for Chronic Kidney Disease: Validation of the Revised Japanese Guideline."
03/01/2013 - "Patients with false, relative to those with true, isolated-office RH had higher prevalence of microalbuminuria and chronic kidney disease (CKD), significantly higher albumin/creatinine ratio (p < .001), significantly higher 48-h SBP/DBP means by 9.6/5.3 mm Hg (p < .001), significantly lower sleep-time relative SBP and DBP decline (p < .001), and significantly greater prevalence of a non-dipper BP profile (96.9% vs. 38.9%; p < .001). "
01/01/2014 - "The CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) creatinine equation performed better than the MDRD (Modification of Diet in Renal Disease) Study equation in terms of greater accuracy at P30 (76.1% [95% CI, 72.7%-79.5%] vs 68.0% [95% CI, 64.3%-71.7%]; P < 0.001) and improved precision (IQR, 22.6 [95% CI, 19.9-25.3] vs 28.6 [95% CI, 25.8-31.5] mL/min/1.73 m(2); P < 0.001). "
2. IronIBA
3. Vitamin DFDA LinkGeneric
4. ErythropoietinFDA Link
5. HematinicsIBA
6. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
7. cinacalcet (Sensipar)FDA Link
8. Hemoglobins (Hemoglobin)IBA
9. Biological Markers (Surrogate Marker)IBA
10. Cystatin CIBA

Therapies and Procedures

1. Kidney Transplantation
2. Transplants (Transplant)
3. Renal Dialysis (Hemodialysis)
4. Transplantation (Transplant Recipients)
5. Nephrectomy