Generic Name: Clindamycin

  • What is Clindesse?

    Clindesse is a vaginal cream used to treat bacterial vaginal infections in nonpregnant women.

  • What is the most important information I should know about Clindesse?

    Clindesse cream contains a mineral oil that can weaken latex or rubber products (such as condoms or vaginal birth control diaphragms). Do not use such products while you are using Clindesse or for 5 days following treatment with Clindesse. During this time period, condoms may not be reliable for preventing pregnancy or for protecting against HIV (AIDS) and other sexually transmitted diseases.

    Clindesse can cause diarrhea or colitis (inflammation of the colon). This can happen a couple of months after using Clindesse. Tell your doctor immediately if you have diarrhea or colitis.

    Clindesse is for vaginal use only.

    You may experience a vaginal fungal infection following the use of Clindesse, which would require treatment with an antifungal medication.

  • Who should not take Clindesse?

    Do not use Clindesse if you are allergic to it, any of its ingredients, or to similar products such as clindamycin or other lincosamides. Also, do not use Clindesse if you have a history of inflammatory disease of the colon or intestines, or inflammation of the colon with past antibiotic use.

  • What should I tell my doctor before I take the first dose of Clindesse?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Clindesse. Also, talk to your doctor about your complete medical history, especially if you have a history of inflammatory disease of the colon or intestines, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?


    Adults: Insert 1 applicator in your vagina for 1 dose at any time of the day.

  • How should I take Clindesse?

    Use Clindesse exactly as prescribed by your doctor. Do not apply extra doses or use more often without asking your doctor.

    Insert all of the Clindesse cream of 1 applicator into your vagina one time.

    Please review the instructions that came with your prescription on how to properly use Clindesse.

  • What should I avoid while taking Clindesse?

    After you insert Clindesse, do not have vaginal intercourse or use other vaginal products (such as tampons or douches) for at least 7 days.

    Do not put Clindesse in your eyes, mouth, or on your skin. If you accidently get Clindesse in your eyes rinse your eyes with cool tap water immediately and call your doctor.

    Do not use Clindesse for a condition for which it was not prescribed.

    Do not give Clindesse to other people, even if they have the same symptoms you have. It may harm them.

  • What are possible food and drug interactions associated with Clindesse?

    No significant interactions have been reported with Clindesse at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Clindesse?


    Side effects may include: back pain, constipation, diarrhea, dizziness, headache, itching, menstrual pain, rash, urinary tract infections, vaginal burning and irritation, vomiting

  • Can I receive Clindesse if I am pregnant or breastfeeding?

    The effects of Clindesse during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Clindesse?

    Clindesse should be given under special circumstances determined by your doctor.

  • How should I store Clindesse?

    Store at room temperature, away from extreme heat.