Unit One

Genome Sequences

Chapter 1: Genome Sequence Acquisition and Analysis


Section 1.1 Defining Genomes

  • What is genomics?
  • How are whole genomes sequenced?
  • Why do databases contain so many partial sequences?
  • How do we make sense of all these bases?
  • Can we predict protein functions?
  • How well are genes conserved in diverse species?
  • How do you know which bases form a gene?
  • How many proteins can one gene make?

Math Minutes:

1.1 What is an E-value?

Information Box:

1.1 Which draft sequence is better?


Section 1.2 What have we learned from the human genome draft sequences?

  • Overview of human genome first draft.
  • Can we describe a typical human gene?
  • When are the data sufficient?
  • Can the genome alter gene expression without changing the DNA sequence?

Information Box:

1.2 Whose DNA did we sequence?


Chapter 2: Genome Sequence Acquisition and Analysis

Section 2.1 Evolution and Genomes

  • How did eukaryotes evolve?
  • What is the origin of our species?

Math Minutes:

2.1 Are the hit numbers significantly different?
2.2 How do you know if the tree is right?


Section 2.2 Genomic Identifications

  • How can we identify biological weapons?
  • How long can DNA survive?
  • How did tuberculosis reach North America?
  • How are newly emerging diseases identified?

Section 2.3 Biomedical Genome Research

  • Can we use genomic sequences to make new vaccines?
  • Can we make new types of antibiotics?
  • Can we invent new types of medications?
  • How can E. coli be lethal and in our intestines at the same time?

Math Minutes:

2.3 How can you tell if base compositions are different?


Methods for Genomic Sequences

15 Second Biographies of Genomic Sequence Researchers

Cell Web Front Page

Genomics Course Outline and Syllabus

Genomics Schedule

Molecular Biology Course

Biology Course Materials

Biology Home Page

College Home Page search

Send comments, questions, and suggestions to: macampbell@davidson.edu