Dimercaptosuccinic acid (DMSA) is a drug which is approved by the FDA for use in acute metal poisoning.  Its trade name is Chemet. 

     DMSA is considered to be much safer than DMPS.  In research studies, DMPS proved to be three times more toxic than DMSA.  I've been told that DMSA is much less likely to bind to the beneficial minerals, as DMPS does. 

     In addition, there are claims that DMSA will cross the blood brain barrier to access mercury accumulations in the brain.  The chemists I have spoken to say that it will not.  However, when any chelator loses its bond to the toxic metal, it can drop the metal into the bloodstream.  From there, certain forms of metals can cross the blood brain barrier. 

     DMSA is commonly prescribed as an oral administration.  This makes it more convenient for the patient, less profitable for the doctor.  Oral administration is generally safer, because a patient can start with a low dose to test tolerance levels.  If you're having a bad reaction, you can stop, or reduce the dosage.

     By contrast, DMPS is commonly given by infusion or injection (parenteral administration).  Controlling an adverse reaction is difficult, if not impossible, when this mode of administration is used.

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