Definitions for fibrinolysinˌfaɪ brəˈnɒl ə sɪn

This page provides all possible meanings and translations of the word fibrinolysin

Random House Webster's College Dictionary

fi•bri•nol•y•sinˌfaɪ brəˈnɒl ə sɪn(n.)

  1. Category: Biochemistry

    Ref: plasmin.

Origin of fibrinolysin:


Princeton's WordNet

  1. plasmin, fibrinolysin(noun)

    an enzyme that dissolves the fibrin of blood clots


  1. Fibrinolysin

    Fibrinolysin is an enzyme derived from plasma of bovine origin or extracted from cultures of certain bacteria. It is used locally only and exclusively together with the enzyme desoxyribonuclease. Fibrinolysin and desoxyribonuclease both act as lytic enzymes. The combination is available as ointment containing 1 BU fibrinolysin and 666 BUs desoxyribonuclease per gram. Fibrinolysin attacks and inactivates fibrin molecules occurring in undesirable exudates on the surface of the human body and on human mucosa, e.g., in superficial wounds and burns, while desoxyribonuclease targets and destroys DNA. The combination of the two enzymes has a synergistic effect on necrotic but not on living tissue. According to the manufacturer the ointment provides enhanced wound cleaning and accelerates the healing process. Both enzymes are marginally resorbed into systemic circulation because of their very high molecular weight and their macromolecular structure. The activity of both enzymes is almost completely exhausted after 24 hours. Usually, it is necessary to repeat the application every 6 to 8 hours until healing becomes complete.

U.S. National Library of Medicine

  1. Fibrinolysin

    A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.


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