FIGURE 1 | The innate and adaptive immune response.

From the following article:

Cytokines in cancer pathogenesis and cancer therapy

Glenn Dranoff

Nature Reviews Cancer 4, 11-22 (January 2004)


Cytokines in cancer pathogenesis and cancer therapy

The innate immune response functions as the first line of defence against infection. It consists of soluble factors, such as complement proteins, and diverse cellular components including granulocytes (basophils, eosinophils and neutrophils), mast cells, macrophages, dendritic cells and natural killer cells. The adaptive immune response is slower to develop, but manifests as increased antigenic specificity and memory. It consists of antibodies, B cells, and CD4+ and CD8+ T lymphocytes. Natural killer T cells and gammadelta T cells are cytotoxic lymphocytes that straddle the interface of innate and adaptive immunity.

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