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[[Category:German neuroscientists|Alzheimer, Alois]]
[[Category:German neuroscientists|Alzheimer, Alois]]
[[Category:Alzheimer's disease|Alzheimer, Alois]]
[[Category:Alzheimer's disease|Alzheimer, Alois]]
[[Category:1864 births|Alzheimer, Alois]]
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{{enWP|Alois Alzheimer}}

Latest revision as of 05:29, February 11, 2007




Aloysius "Alois" Alzheimer (14 June 1864, Marktbreit, Bavaria - 19 December 1915, Breslau, now Wrocław, Poland) was a German psychiatrist and neuropathologist and a colleague of Emil Kraepelin. Alzheimer is credited with the first published case of "presenile dementia", which Kraepelin would later identify as Alzheimer's disease.



In 1901, Alzheimer observed a patient at the Frankfurt Asylum named Mrs. Auguste Deter. The 51-year-old patient had strange behavioral symptoms, including a loss of short-term memory. This patient would become his obsession over the coming years. In April 1906, Mrs. Deter died and Alzheimer had the patient records and the brain sent to Munich where he was working at Kraepelin's lab. Together with two Italian physicians, he would use the staining techniques to identify amyloid plaques and neurofibrilary tangles. A speech given on 3 November 1906 would be the first time the pathology and the clinical symptoms of presenile dementia would be presented together.[1]

Since German was the common language of science and especially of psychology of the time, Kraepelin's use of Alzheimer's disease in a textbook would make the name famous. By 1911, the disease was being used by European physicians to diagnose patients in the US. [1]

In mid-December 1915, Alzheimer fell ill on the train on the way to the University of Breslau, where he had been appointed professor of psychiatry in 1912. Most probably he had a streptococcal infection and subsequent rheumatic fever and [kidney failure. He died of heart failure at the age of 51 in Breslau.

External links Edit


  1. 1.0 1.1 Maurer K., Maurer U. (2003). Alzheimer: The Life of a Physician and Career of a Disease, New York: Columbia University Press. ISBN 0-231-11896-1.

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