Skip to Content

Cleocin Ovules

Generic Name: clindamycin vaginal (klin da MYE sin)
Brand Name: Cleocin Ovules, Cleocin Vaginal, ClindaMax, Clindesse

What is Cleocin Ovules (clindamycin vaginal)?

Clindamycin is an antibiotic that fights bacteria.


Clindamycin vaginal may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Cleocin Ovules (clindamycin vaginal)?

You should not use clindamycin vaginal if you have an intestinal disorder such as colitis or Crohn's disease.

What should I discuss with my healthcare provider before using Cleocin Ovules (clindamycin vaginal)?


  • an intestinal disorder such as ulcerative colitis or Crohn's disease; or

  • if you have ever had severe diarrhea caused by using an antibiotic.

To make sure clindamycin vaginal is safe for you, tell your doctor if you have any type of intestinal disorder.


Clindamycin vaginal may contain ingredients that can weaken a condom and cause it to break. An unintended pregnancy could result. Avoid using a condom as a birth control method while you are using clindamycin vaginal and for at least 72 hours (3 days) after your treatment ends.

It is not known whether clindamycin vaginal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I use Cleocin Ovules (clindamycin vaginal)?


Clindamycin vaginal is usually used at bedtime for 3 to 7 nights in a row.



Apply clindamycin vaginal using only the disposable applicators provided with the medicine. Use a new applicator each time you use the medicine, then throw the applicator away. Do not clean or reuse a disposable applicator.

Clindamycin vaginal can cause burning or irritation if you accidentally get it in your eyes. If this does happen, rinse with plenty of cool water.

If you need surgery, tell the surgeon ahead of time that you are using clindamycin vaginal. You may need to stop using the medicine for a short time.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Clindamycin vaginal will not treat a viral infection such as the flu or a common cold.

Call your doctor if your symptoms do not improve, or if they get worse while using clindamycin vaginal.



What happens if I miss a dose?


It is best to use clindamycin vaginal only at bedtime, or while you will be resting or lying down.

What happens if I overdose?


What should I avoid while using Cleocin Ovules (clindamycin vaginal)?


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using clindamycin vaginal and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Cleocin Ovules (clindamycin vaginal) side effects


Stop using clindamycin vaginal and call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody.

Common side effects may include:

  • vaginal pain; or

  • symptoms of a fungal (yeast) infection--vaginal itching or discharge.


See also: Side effects (in more detail)

What other drugs will affect Cleocin Ovules (clindamycin vaginal)?

It is not likely that other drugs you take orally or inject will have an effect on clindamycin used in the vagina. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Where can I get more information?

  • Your pharmacist can provide more information about clindamycin vaginal.


Date modified: October 14, 2016
Last reviewed: February 23, 2016