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What is LADA? (Latent Auto-Immune Diabetes in Adults)

There are two types of diabetes mellitus:

Type 1 diabetes, which is often diagnosed at a young age and is due to autoimmune destruction of insulin producing cells in the pancreas; patients depend on insulin treatment.

Type 2 diabetes is non-insulin requiring and usually develops after 30 years of age; only a small proportion of cases eventually require treatment with insulin.

In recent years, it has been discovered that some non-insulin requiring diabetic patients present with blood serum autoantibodies usually associated Type 1 diabetes. This form of non-insulin requiring autoimmune diabetes has been defined as LADA (Latent Autoimmune Diabetes in the Adults).

Little is known about LADA including its epidemiology, genetic susceptibility, natural history, metabolic characteristics and clinical progression.

Please note, the database is currently under maintenance at QMUL. Any questions about the database should be directed to M I Hawa.

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