Disease-gene associations mined from literature

Human genes for gonadal dysgenesis

Gonadal dysgenesis [DOID:14447]

Gonadal dysgenesis is a term used to describe multiple reproductive system development disorders. They are conditions of genetic origin. It is characterized by a progressive loss of primordial germ cells on the developing gonads of an embryo. This loss leads to extremely hypoplastic (underdeveloped) and dysfunctioning gonads mainly composed of fibrous tissue, hence the name streak gonads - i.e., a form of aplasia in which the ovary is replaced by a functionless tissue, as found in turner's syndrome.

Synonyms:  gonadal dysgenesis,  DOID:14447,  Gonadal dysgenesis (disorder),  Gonadal dysgenesis NOS,  Gonadal dysgenesis NOS (disorder) ...

Linkouts:  OMIM