How Does The Human Eye Work?

To understand Keratoconus, we must first understand how the eye enables us to see, and what role the cornea plays in this process.

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Because the keratoconus cornea is irregular and cone shaped, light rays enter the eye at different angles, and do not focus on one point the retina, but on many different points causing a blurred, distorted image.

In summary, the cornea is the clear, transparent front covering which admits light and begins the refractive process. It also keeps foreign particles from entering the eye.

The pupil is an adjustable opening that controls the intensity of light permitted to strike the lens. The lens focuses light through the vitreous humor, a clear gel-like substance that fills the back of the eye and supports the retina.

The retina receives the image that the cornea focuses through the eye’s internal lens and transforms this image into electrical impulses that are carried by the optic nerve to the brain. We can tolerate very large scars on our bodies with no concern except for our vanity. This is not so in the cornea. Even a minor scar or irregularity in the shape can impair vision. No matter how well the rest of the eye is functioning, if the cornea is scarred, clouded or distorted, vision will be affected.

In keratoconus, the irregular shape of the cornea does not allow it to do its job correctly, leading to distortion of the image it passed to the retina and transmitted to the brain.


The eye is enclosed by a tough white sac, the sclera. The cornea is the transparent window in this white sac which allows the objects you are looking at to be carried in the form of light waves into the interior of the eye.

The surface of the cornea is where light begins its journey into the eye. The cornea’s mission is to gather and focus visual images. Because it is out front, like the windshield of an automobile, it is subject to considerable abuse from the outside world.

The cornea is masterfully engineered so that only the most expensive manmade lenses can match its precision. The smoothness and shape of the cornea, as well as its transparency, is vitally important to the proper functioning of the eye. If either the surface smoothness or the clarity of the cornea suffers, vision will be disrupted.


Layers of the CorneaAlthough appearing to be one clear membrane, the cornea is composed of five distinct layers of tissue, each with its own function.

  • Epithelium is the thin outermost layer of fast-growing and easily-regenerated cells.
  • Bowman’s layer consists of irregularly-arranged collagen fibers and protects the corneal stroma. It is 8 to 14 microns thick.
  • Stroma, the transparent middle and thickest layer of the cornea is made up of regularly-arranged collagen fibers and keratocytes (specialized cells that secrete the collagen and proteoglycans needed to maintain the clarity and curvature of the cornea)
  • Descemet’s membrane is a thin layer that serves as the modified basement membrane of the corneal endothelium.
  • Endothelium is a single layer of cells responsible for maintaining proper fluid balance between the aqueous and corneal stromal compartments keeping the cornea transparent.