Online ISSN: 2515-8260

Keywords : CNS

Neurotoxicity: A Devastation to CNS

Pratik Singh; Dr. Priyanka Verma

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4831-4840

The word “neuro” is originated from the classical Greek word “neuron” which means nerves and nervous system which plays a very essential role in functioning of different body parts of humans and animals.[1] Neurotoxins are those kinds of toxic substances which are when encountered with living body by what’s so ever way i.e. Cutaneous, Sub-cutaneous, Ocular, Muscular or Intravenous, causes maladaptive and detrimental behaviour of CNS (Central nervous system) which leads to evolve various diseases and ultimately death. Neurotoxicity is the direct or indirect ramifications of nerve cells and nervous systems which especially effects to the cellular metabolic processes on which CNS mutually depends.[2] Neurotoxicity is usually self-sustaining and rarely progressive when discontinued in exposure with body but there can be delay in between the contact time and the neurotoxic effects.[3]

Wonders of Phytomedicine in the management of neurological disorders

Gurria .; Iqbaljit Kaur; Srijana Sharma; Keerti Bhardwaj

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 2899-2914

Neurological disorders exhibit its impact on global health. The term neurological disorders mean any condition that occurs due to dysfunction in nervous system or brain as a result shows plethora of symptoms such as sensation loss, pain, muscle weakness, etc. Utilization of synthetic drugs to treat neurological disorder is quite challenging as it has some drawbacks like not cost effective, unavoidable and serious side effects as well as less patient compliance. Therefore, phytomedicines has been preferred as an alternative treatment of neurological disorders due to its variety of merits like cheap, exert negligible side effects, etc. Herbs can be prescribed as a single entity or mixture of different plants against such disorders. This review describes the phytomedicines used to treat CNS specific pharmacologic effects (like anxiolytic, anti-convulsant, analgesic, etc.), ranging from entire plant, bark, flowers, roots, fruit, stem and seeds.