Ayurvedic Treatment for Chaple Syndrome


Genetic disorder is a disease that is caused by defective genes or mutation in an individual’s DNA sequence. If there is any change in a person’s DNA then it causes genetic abnormalities. These abnormalities cause change in a part or whole DNA sequence. There are various genetic disorders such as down syndrome, albinism, sickle cell anemia, thalassemia, Chaple syndrome etc. In this article we will discuss this disease named Chaple syndrome and its ayurvedic management in detail.

Chapel’s Syndrome


Chaple syndrome is a rare genetic disorder of the immune system. It stands for CD55 deficiency and with hyperactivation of angiopathic thrombosis and severe protein losing enteropathy (PLE). This disease occurs in childhood and can be a life threatening condition.

Now let’s Just Discuss the Ayurvedic View on Genetic Disorders

As we know, it is a genetic disorder, we can correlate this with beeja dosha i.e. deformity in shukra and artava1.

Beejdosha (genetic deformity) totally depends on which part of the beejabhaga (genes and chromosomes) are affected. According to that, the offspring are developed. If there is not any deformity then a perfectly fine offspring is produced by the affected parents. So both the things are seen that children might be like their parents or not. Acharya said that indriya (senses) are atmaja and its presence or absence totally depends on the poorva janma krit karma (past deeds). That’s why the offspring might be affected or not.


It is caused by deleterious mutations in the CD55 gene. It is a primary autosomal recessive inherited condition. Child inherited the copies of the defective gene from both the parents which results in homozygous defects.

Clinical features/Signs and Symptoms

The patient shows following symptoms:

  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Weight loss
  • Edema
  • Deficiency in iron, calcium, magnesium, vit-D and vit- B12 (due to chronic malabsorption)


  • Doctor will do a thorough examination for diagnosing this disease. In blood investigation, there is Hypoproteinemia (due to severe protein losing enteropathy). These patients are generally diagnosed through clinical presentation, histology and genetic testing.
  • Histopathological report suggests that there is extensive lymphangiectasia (pathological dilatation of lymph vessels.

Herbal Treatment for Chaple Syndrome

Planet Ayurveda is a worldwide leading manufacturing company. This company manufactures various herbal products. These herbal products are 100% natural and vegetarian. They are made under the guidance of expert vaidyas and also made with the standardized extracts of various potential herbs. Also these products are free from chemicals and preservatives and have no side-effects.

We provide following herbal Remedies for Chaple syndrome treatment

  1. Ashwagandha Capsules
  2. Punarnava Mandur
  3. Immune Booster
  4. Wheatgrass Powder
  5. Pitta Balance
  6. Swarna Basant Malti Ras

Chapel 'S Syndrome

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1. Ashwagandha Capsules

This is a single herb formulation. It is the best natural stress buster herb. This is made using standardized extracts of Ashwagandha (Withania somnifera). Effectively acts as medhya (nerve tonic). Provides strength to the muscles and calms down the system. It balances Vata dosha.

Dosage: 1 capsule twice a day with plain water after meals.

2. Punarnava Mandur

This is a classical Ayurvedic formulation. This formulation is effective in water retention and pedal edema conditions. This is the natural solution to clear toxins from the body. These are natural herbal diuretic tablets. The herbs in this are effective to improve blood count, remove toxins such as Punarnava (Boerhavia diffusa), Shunti (Zingiber officinale), Pippali (Piper longum), Maricha (Piper nigrum), Amalaki (Emblica officinalis), Haritaki (Terminalia chebula).

Dosage: 2 tablets twice after meals with plain water.

3. Immune Booster

This is a poly herbal formulation and it is a natural immune booster product. The ingredients in this are helpful in enhancing immunity such as Grape seed (Vitis vinifera), Cow colostrum (Bovine colostrums), Bhumi amla (Phyllanthus niruri), Amalaki (Emblica officinalis), It builds up long lasting immunity in children as well as adults.

Dosage: 2 capsules twice a day after meals.

4. Pitta Balance

This is a poly herbal formulation. This formula is made from coral calcium (Praval pishti), agate calcium (Akik pishti), an ayurvedic calcium compound (Kamdudha ras and Jawara mohra pishti), pearl calcium (Mukta pishti), extracts of Guduchi (Tinospora cordifolia). This is helpful in digestion and improves digestive power as it balances the pitta dosha.

Dosage: 1 capsule twice a day after meals.

5. Swarna Basant Malti Rasa

This is a herbo-mineral formulation. This formulation is effective in providing nutrition to the dhatus (body tissues). This is made from Mukta bhasma (Pearl ash), Swarna bhasma (Gold ash), Shudha Parada (purified Mercury), Shuddha Gandhak (purified sulphur). These all are best for enhancing immunity. This formulation is best for genetic disorders.

Dosage: 1 tablet to be chewed twice daily after meals.

6. Wheat Grass Powder

This is a pure herbal powder. This is rich in vitamins, minerals, natural anti-oxidant. It is popular as green blood as it is rich in natural nutrients. It is effective in every disease by enhancing immunity. It detoxifies the organs and blood and helps to clear the skin. It is made from fresh small leaves of baby wheat plants.

Dosage: 1 tsp twice daily with water after, 1 hour after meals.



As we see that there is no exact treatment in Allopathy for genetic disorders. So it’s better to switch to Ayurvedic medicines. They will treat the disease from its root cause and further cause no side-effects and complications.


  1. Charaka sharirsthan 3/17


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Dr. Vikram Chauhan