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Review: could Methotrexate cause Basal cell carcinoma?

Summary: Basal cell carcinoma is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 720 have Basal cell carcinoma. Find out below who they are, when they have Basal cell carcinoma and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Basal cell carcinoma >>>


Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Basal cell carcinoma

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills) has been reported by people with rheumatoid arthritis, osteoporosis, multiple sclerosis, high blood pressure, osteopenia.(latest reports from Basal cell carcinoma 5,209 patients)

On Nov, 25, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 720 people (0.55%) have Basal Cell Carcinoma.

Trend of Basal cell carcinoma in Methotrexate reports

Time on Methotrexate when people have Basal cell carcinoma * :

Basal cell carcinoma10.94%10.94%21.88%15.62%18.75%15.62%6.25%

Gender of people who have Basal cell carcinoma when taking Methotrexate * :

Basal cell carcinoma67.35%32.65%

Age of people who have Basal cell carcinoma when taking Methotrexate * :

Basal cell carcinoma0.00%0.81%0.16%1.13%1.77%14.01%16.26%65.86%

Severity of Basal cell carcinoma when taking Methotrexate ** :

leastmoderateseveremost severe
Basal cell carcinoma0.00%0.00%100.00%0.00%

How people recovered from Basal cell carcinoma ** :

while on the drugafter off the drugnot yet
Basal cell carcinoma100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (470 people, 65.28%)
  2. Osteoporosis (56 people, 7.78%)
  3. Crohn's disease (49 people, 6.81%)
  4. Psoriatic arthropathy (43 people, 5.97%)
  5. Prophylaxis (37 people, 5.14%)

Top co-used drugs for these people * :

  1. Folic acid (409 people, 56.81%)
  2. Remicade (319 people, 44.31%)
  3. Prednisone (140 people, 19.44%)
  4. Aspirin (113 people, 15.69%)
  5. Omeprazole (104 people, 14.44%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.


Do you have Basal Cell Carcinoma while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Basal Cell Carcinoma
- support group for people who take Methotrexate
- support group for people who have Basal Cell Carcinoma

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More questions for: Methotrexate, Basal cell carcinoma


  • Humira: my experience
  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...
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  • Personalized review of arava (1 response)
    (Posted by a 65 year old woman who has Rheumatoid Arthritis, and takes Methotrexate)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate ...

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